Modeling Proteins

When studying a proteins function it is insufficient to analyze its aminoacidic sequence. Although it provides very useful information most proteins functions, if not all, relay on their tridimensional structure which requires a much more complex set of tools both in silico and experimental. For this project it is important to have tridimensional models of the enzymes mainly because they are not well known proteins with a detailed characterization nor do they have experimental tridimensional structures proposed in the available international databases (in fact one of them is classified as an hypothetical protein). Knowing the possible structure of these enzymes is very useful to compare them to other enzymes found to have a sequence and function homology and to further extent this homology with their structure, therefore assuring to a certain degree that the proteins expressed will work the way it is needed.

Bioinformatic Tools