Team:LIKA-CESAR-Brasil

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     <p>Thank you for your visit! We are under construction. <br>
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    <p style="color:#E7E7E7"> <a href="https://2014.igem.org/wiki/index.php?title=Team:LIKA-CESAR-Brasil&action=edit"style="color:#F36C1D"> Click here  to edit this page!</a></p></td>
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  <p><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil"style="color: #FFFFFF; border-color: #F36C1D;"><strong>Home</strong></a> </p></td>
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  <strong><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Team"style="color: #FFFFFF"> Team </a> </strong></td>
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  <strong><a href="https://igem.org/Team.cgi?year=2014&team_name=LIKA-CESAR-Brasil"style="color: #FFFFFF"> Official Team Profile </a></strong></td>
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<td style="color: #F36C1D;" align="center"  height ="45px" onMouseOver="this.bgColor='#D82A35'" onMouseOut="this.bgColor='#F36C1D'" bgColor=#F36C1D> 
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  <strong><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Project"style="color: #FFFFFF"> Project</a></strong></td>
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<td style="" align="center"  height ="45px" onMouseOver="this.bgColor='#D82A35'" onMouseOut="this.bgColor='#F36C1D'" bgColor=#F36C1D>
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  <strong><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Parts"style="color: #FFFFFF"> Parts</a></strong></td>
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<td style="" align="center" height ="45px" onMouseOver="this.bgColor='#D82A35'" onMouseOut="this.bgColor='#F36C1D'" bgColor=#F36C1D>
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  <strong><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Modeling"style="color: #FFFFFF;"> Modeling</a></strong></td>
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<td style="" align="center" height ="45px" onMouseOver="this.bgColor='#D82A35'" onMouseOut="this.bgColor='#F36C1D'" bgColor=#F36C1D> 
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  <strong><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Notebook"style="color: #FFFFFF;"> Notebook</a></strong></td>
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<td style="" align="center"  height ="45px" onMouseOver="this.bgColor='#D82A35'" onMouseOut="this.bgColor='#F36C1D'" bgColor=#F36C1D>
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  <strong><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Safety"style="color: #FFFFFF"> Safety </a></strong></td>
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<td  height ="45px" align="center" nowrap bgColor=#F36C1D style="" onMouseOver="this.bgColor='#D82A35'" onMouseOut="this.bgColor='#F36C1D'">
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  <strong><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Attributions"style="color: #FFFFFF;"> Attributions </a></strong></td>
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<tr>
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</head>
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  <td><strong>Team Information</strong></td>
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  <td>&nbsp;</td>
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  <td><strong>Upload pictures of your team!</strong></td>
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</tr>
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<tr>
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  <td width="48%" align="left"  valign="top">
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  <p>You can write a background of your team here. Give us a background of your team, the members, etc. Or tell us more about something of your choosing.</p>
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  <p> You can look at what other teams did to get some inspiration! Here are a few examples:</p>
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  <ul>
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    <li><a href="https://2013.igem.org/Team:Evry/Team">2013 Evry</a></li>
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    <li><a href="https://2013.igem.org/Team:Cornell/team">2013 Cornell</a></li>
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    <li><a href="https://2013.igem.org/Team:UANL_Mty-Mexico/Team">2013 UANL Mty-Mexico</a></li>
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    <li><a href="https://2013.igem.org/Team:Korea_U_Seoul/Team/Korea_University">2013 Korea U Seoul</a></li>
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  </ul>
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  </td>
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  <td width="4%" > </td>
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  <td width="48%" align="left" valign="top">
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  <p>We provide a server where you can upload images for your wiki!</p>
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  <p> Add pictures of your team members, advisors, instructors, lab, institution and everything you wish to show! </p>
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  <a href="https://2014.igem.org/Special:Upload"><img src="" width="100px" height="100px"></a> <a href="https://2014.igem.org/Special:Upload"><img src="" width="100px" height="100px"></a> </a> <a href="https://2014.igem.org/Special:Upload"><img src="" width="100px" height="100px"></a> <br>
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  <a href="https://2014.igem.org/Special:Upload">Click here to upload! </a> </td>
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        <li><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil">HOME</a></li>
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<tr>
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  <td ><strong>Tips for the Team Page</strong></td>
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                <a href="#" class="dropdown-toggle" data-toggle="dropdown">TEAM<span class="caret"></span></a>
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  <td >&nbsp;</td>
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  <td nowrap >&nbsp;</td>
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                  <li><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Partnerships">Partnerships</a></li>
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</tr>
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                  <li><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/TeamProfile">Official Team Profile</a></li>
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                  <li><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Advisors">Advisors</a></li>
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                  <li><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Overview">Overview</a></li>
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                  <li><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Robot">Robot</a></li>
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                  <li><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/ColiAlert">ColiAlert</a></li>
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          <li><a href="biosensor.html">Biosensor</a></li>
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              </ul>
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              </li>
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        <li class="dropdown">
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                <a href="#" class="dropdown-toggle" data-toggle="dropdown">PARTS<span class="caret"></span></a>
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                  <li><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Biobricks">Biobricks</a></li>
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                  <li><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Notebook">Notebook</a></li>
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                </ul>
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              </li>       
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        <li class="dropdown">
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                <a href="#" class="dropdown-toggle" data-toggle="dropdown">HUMAN PRACTICE<span class="caret"></span></a>
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                  <li><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Lectures">Lectures</a></li>
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                  <li><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Society">Survey and Society Interaction</a></li>
 +
  <li><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/MeetUp ">Meet Up</a></li>
 +
                  <li><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/SocialImpact">Social Impact</a></li>
 +
                </ul>
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              </li>
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        <li><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Safety">SAFETY</a></li>
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        <li><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Atribuitons">ATRIBUITIONS</a></li>
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        <li class="igem-logo"><a href="https://2014.igem.org/"></a></li>
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        <h2>Synthetic Biology and Robotics - The Integration that can Save Lives</h2>
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        <p>The LIKA-CESAR BRASIL proposes the development of a biosensor for the detection of breast cancer with the help of synthetic biology and robotics. The idea was to build a robotic system linked to genetic engineering capable of processing and prepare small samples of blood in an automated manner.</p>
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        <p>For this our team, created the Coli Alert for the BreastBotSensor.  This system is one robot to DNA/RNA extraction coupled by an electrochemical biosensor and linked to one quality control, the ColiAlert, responsible to confirm the process of nucleic acid extraction.</p>
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        <p>The team believes that the best way to solve problems is joining technologies. For this, we think that synthetic biology should go hand in hand with robotics and information technology. Then our project was to join the synthetic biology with the robots, aiming to fight against to the one of biggest health problems: The Breast Cancer.</p>
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                            <source src="https://static.igem.org/mediawiki/2014/5/5b/CESAR_%26_LIKA_-_Against_breast_cancer.ogg" type='video/ogg; codecs="theora, vorbis"'/>
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          <p>The bot was built by Team LIKA-CESAR-Brasil. It is a robot responsible for automating the extraction of nucleic acids from blood. Most of the pieces were created from a 3D printer to cheapen the system.  It consists of a eletric syringe, a robotic arm and a centrifuge together to perform the entire procedure. Nucleic acids extracted by Bot, will be sent for analysis in BreastSensor.</p>
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  <li> Include pictures of your teammates, don’t forget instructors and advisors! </li>
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  <li> You can add a small biography or a few words from each team member, tell us what you like, and what motivates to participate in iGEM. </li>
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          <h2>ColiAlert</h2>
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  <li>Take team pictures! Show us your school, your lab and little bit of your city.</li>
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          <p>The team also made an alert system of cell lysis called ColiAlert . This system was created to be the quality control of Bot. It is a genetically engineered bacteria able to alert the process of cell lysis by color change. Under normal conditions the ColiAlert is pink, but after cell lysis, it becomes yellow. After going through this system of quality control, the sample is ready to proceed to BreastSensor.</p>
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          <h2>BreastSensor</h2>
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          <p>To finalize the project, the team created the BreastSensot. It is an electrochemical DNA biosensor capable of recognizing a biomarker for breast cancer. This  biomarker is a which has a high expression in the early stage of this type of cancer.The biosensor constructed has the ability to perform an early diagnosis of a patient with breast cancer.</p>
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<a href="http://www.ufpe.br/lika/"><img src="https://static.igem.org/mediawiki/2014/2/2f/Img_logolika.png" alt="Marca LIKA"></a>
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<a href="http://www.cesar.org.br"><img src="https://static.igem.org/mediawiki/2014/d/d7/Img_logocesar.png" alt="Marca CESAR"></a>
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Latest revision as of 02:45, 18 October 2014

LIKA | CESAR

Synthetic Biology and Robotics - The Integration that can Save Lives

The LIKA-CESAR BRASIL proposes the development of a biosensor for the detection of breast cancer with the help of synthetic biology and robotics. The idea was to build a robotic system linked to genetic engineering capable of processing and prepare small samples of blood in an automated manner.

For this our team, created the Coli Alert for the BreastBotSensor. This system is one robot to DNA/RNA extraction coupled by an electrochemical biosensor and linked to one quality control, the ColiAlert, responsible to confirm the process of nucleic acid extraction.

The team believes that the best way to solve problems is joining technologies. For this, we think that synthetic biology should go hand in hand with robotics and information technology. Then our project was to join the synthetic biology with the robots, aiming to fight against to the one of biggest health problems: The Breast Cancer.

Bot

The bot was built by Team LIKA-CESAR-Brasil. It is a robot responsible for automating the extraction of nucleic acids from blood. Most of the pieces were created from a 3D printer to cheapen the system. It consists of a eletric syringe, a robotic arm and a centrifuge together to perform the entire procedure. Nucleic acids extracted by Bot, will be sent for analysis in BreastSensor.

ColiAlert

The team also made an alert system of cell lysis called ColiAlert . This system was created to be the quality control of Bot. It is a genetically engineered bacteria able to alert the process of cell lysis by color change. Under normal conditions the ColiAlert is pink, but after cell lysis, it becomes yellow. After going through this system of quality control, the sample is ready to proceed to BreastSensor.

BreastSensor

To finalize the project, the team created the BreastSensot. It is an electrochemical DNA biosensor capable of recognizing a biomarker for breast cancer. This biomarker is a which has a high expression in the early stage of this type of cancer.The biosensor constructed has the ability to perform an early diagnosis of a patient with breast cancer.

Marca LIKA Marca CESAR