Team:Cambridge-JIC

From 2014.igem.org

(Difference between revisions)
 
(150 intermediate revisions not shown)
Line 1: Line 1:
-
{{:Team:Cambridge-JIC/Templates/header_prototype2}}
+
{{:Team:Cambridge-JIC/Templates/header_prototype3}}
 +
<html lang="en">
 +
<head>
 +
<meta http-equiv="Content-Type" content="text/html; charset=UTF-8">
 +
    <style>
 +
#contentSub, #footer-box, #catlinks, #search-controls, #p-logo, .printfooter, .firstHeading,.visualClear {display: none;} /*-- hides default wiki settings --*/
 +
</style>
 +
</head>
 +
    <body>
 +
    <div class="intro-header">
 +
        <div class="container">
 +
            <div class="row">
 +
                <div class="col-lg-9">
 +
                    <div class="intro-message">
 +
                                             
 +
                    </div>
 +
                </div>
 +
            </div>
 +
        </div>
 +
        <!-- /.container -->
 +
    </div>
 +
    <!-- /.intro-header -->
-
<html>
 
-
<!--Debutante message-->
+
    <div class="content-section-a">
-
<br>
+
        <div class="container">
-
<div align="center">
+
            <div class="row">
-
Hello and Welcome to the Cambridge 2014 iGEM Wiki!
+
                <div class="col-lg-3 col-lg-offset-0 col-sm-push-7  col-sm-6">
-
<br>
+
                    <img class="img-responsive" src="https://static.igem.org/mediawiki/2014/5/5e/Round_coin.png" width="300px" alt="">
-
Here, you can find out all about our project, results and adventures.
+
                </div>
-
<br>
+
                <div class="col-lg-7 col-sm-pull-3  col-sm-6">
-
Follow the links to enter the world of the iGEM Cambridge team and be ready to be captivated!
+
                    <hr class="section-heading-spacer">
-
<br>
+
                    <div class="clearfix"></div>
-
You can contact us at:
+
                    <h2 class="section-heading">mösbi - a plant biosensor for everyone</h2>
-
<a href="mailto:igemcambridge2014@gmail.com">igemcambridge2014@gmail.com</a>
+
                    <p class="lead"><b>mӧsbi</b> stands for <b>m</b>archantia <b>o</b>pen-<b>s</b>ource <b>bi</b>osensor. mӧsbi encapsulates the team's vision of creating a user-friendly, open-source biosensor using the liverwort <i>Marchantia polymorpha</i>. With its sturdy genetic framework and modularity, mӧsbi represents a new step in popularising synthetic biology and making it accessible to a large audience. Click <a href="https://2014.igem.org/Team:Cambridge-JIC/Project/Overview">here</a> to find out more.</p>
-
</div>
+
                </div>
-
<br>
+
            </div>
 +
        </div>
 +
        <!-- /.container -->
 +
    </div>
-
<div id="project_description">
 
-
<h3>Project Description: an Open-Source BioSensor</h3>
 
-
<p>
 
-
We are establishing the first Open-Source Biosensor with a plug n' play philosophy using the new upcoming multicellular chassis, Marchantia Polymorpha.
 
-
Sensing is critical to all living things. Sensing allows us to detect to our environment, adapt to it and know the effects our our own actions and learn from them. With detection comes an ability to predict the effects of actions, an understanding of the mechanism and ultimately a lead into controlling the system. Without sensing, all units of life would act as independent unit.
+
    <!-- /.content-section-b -->
-
Ideal sensors are reliable, accurate and unobtrusive. Plants as bio-sensors fulfil these requirements and have the further benefit of being inexpensive and self-reproducing.
+
    <div class="content-section-b">
-
</p>
+
        <div class="container">
-
<p>
+
            <div class="row">
-
Our aim is to use the primitive plant Marchantia Polymorpha as a flexible biosensor. The input, processing and output functionalities are parcelled into modules which are linked using metabolites and inducible promoters. The modules can easily be interchanged and added, allowing many devices to be constructed from the same library of components: plug and play.  
+
                <div class="col-lg-7 col-lg-offset-0 col-sm-push-3  col-sm-6">
-
</p>
+
                    <hr class="section-heading-spacer">
-
<p>
+
                    <div class="clearfix"></div>
-
Our vision is to produce input, processing and output plants which can be combined through Mendelian crossing. We want to make home plant biosensors accessible and fun to the public in the same way as the Arduino has popularized electronic hacking.
+
                    <h2 class="section-heading"><i>Marchantia polymorpha</i> as a new chassis</h2>
-
</p>
+
                    <p class="lead"> <i><b>Marchantia polymorpha</b></i> is our novel, eukaryotic multicellular chassis. Being a liverwort, it is one of the most primitive land plants around. Its small size and relative genetic simplicity make it easy to work with and an exciting new model organism in synthetic biology. Content to grow on agar plates, marchantia can be bioengineered in a standard lab with minimal extra equipment. Click <a href="https://2014.igem.org/Team:Cambridge-JIC/Marchantia/Background">here</a> to find out more about the plant and our work to develop the chassis; and <a href="https://2014.igem.org/Team:Cambridge-JIC/Guide">here</a> to learn how to get started using <i>Marchantia</i> in your own iGEM project.</p>
-
</div>
+
                </div>
 +
                <div class="col-lg-3 col-sm-pull-7  col-sm-6">
 +
                    <img class="img-responsive" src="https://static.igem.org/mediawiki/2014/0/07/Cambridge_JIC_Archeg_Fingers_Round.png" alt="" width="300px">
 +
                </div>
 +
            </div>
 +
        </div>
 +
        <!-- /.container -->
 +
    </div>
 +
    <!-- /.content-section-b -->
-
<div align="center"><a href="https://2014.igem.org/wiki/index.php?title=Team:Cambridge-JIC&action=edit">Edit this page</a></div><br>
 
-
<div align="center">
+
    <div class="content-section-a">
-
<img src="https://static.igem.org/mediawiki/2014/e/ea/Marchy_Forest_Cambridge-JIC.jpg" width=500>
+
        <div class="container">
-
</div>
+
            <div class="row">
 +
                <div class="col-lg-3 col-lg-offset-0 col-sm-push-7  col-sm-6">
 +
                    <img class="img-responsive" src="https://static.igem.org/mediawiki/2014/7/72/Round_petri.png" alt="" width="300px">
 +
                </div>
 +
                <div class="col-lg-7 col-sm-pull-3  col-sm-6">
 +
                    <hr class="section-heading-spacer">
 +
                    <div class="clearfix"></div>
 +
                    <h2 class="section-heading">Results</h2>
 +
                    <p class="lead">We successfully transformed hundreds of individual plants, resulting in the first expression of chromoproteins in <i>Marchantia</i>, and probably the first expression of chromoproteins in any plant. We successfully built an arduino-controlled growth chamber, characterised an enzyme new to iGEM and amended the community's knowledge of an existing registry entry. A known <i>Marchantia</i> promoter was also added to the registry, along with 27 candidate promoters from the <i>Marchantia</i>genome. They are part of a <i>Marchantia</i> starter kit part collection that also includes terminators, direction sequences, etc. Finally, we submitted an RFC with collaboration of two other iGEM teams, establishing a unified Type IIS based grammar for plant synthetic biologist: PlantSyntax. Click <a href="https://2014.igem.org/Team:Cambridge-JIC/Results/Lab">here</a> for more result details, and <a href="https://2014.igem.org/Team:Cambridge-JIC/ExecSummary">here</a> for our executive summary.</p>
 +
                </div>
 +
            </div>
 +
        </div>
 +
        <!-- /.container -->
 +
    </div>
 +
    <!-- /.content-section-b -->
-
<br>
 
-
<div align="center">
 
-
Introducing Marchantia Polymorpha, the new iGEM chassis.
+
    <div class="content-section-b">
 +
        <div class="container">
 +
            <div class="row">
 +
                <div class="col-lg-5 col-lg-offset-0 col-sm-push-5  col-sm-6">
 +
                    <hr class="section-heading-spacer">
 +
                    <div class="clearfix"></div>
 +
                    <h2 class="section-heading">Our team</h2>
 +
                    <p class="lead">We are 9 Cambridge science undergraduates from various backgrounds and with all kinds of fascinating and curious interests. Click <a href="https://2014.igem.org/Team:Cambridge-JIC/Team">here</a> to learn more about the team.</p>
 +
                </div>
 +
                <div class="col-lg-5 col-sm-pull-5  col-sm-6">
 +
                    <img class="img-responsive" src="https://static.igem.org/mediawiki/2014/e/ea/Marchy_Forest_Cambridge-JIC.jpg" alt="">
 +
                </div>
 +
            </div>
 +
        </div>
 +
        <!-- /.container -->
 +
    </div>
 +
    <!-- /.content-section-b -->
-
<br>
 
 +
 +
 +
</body>
</html>
</html>

Latest revision as of 01:17, 18 October 2014

Cambridge iGEM 2014

  • Keep in contact with us...

mösbi - a plant biosensor for everyone

mӧsbi stands for marchantia open-source biosensor. mӧsbi encapsulates the team's vision of creating a user-friendly, open-source biosensor using the liverwort Marchantia polymorpha. With its sturdy genetic framework and modularity, mӧsbi represents a new step in popularising synthetic biology and making it accessible to a large audience. Click here to find out more.

Marchantia polymorpha as a new chassis

Marchantia polymorpha is our novel, eukaryotic multicellular chassis. Being a liverwort, it is one of the most primitive land plants around. Its small size and relative genetic simplicity make it easy to work with and an exciting new model organism in synthetic biology. Content to grow on agar plates, marchantia can be bioengineered in a standard lab with minimal extra equipment. Click here to find out more about the plant and our work to develop the chassis; and here to learn how to get started using Marchantia in your own iGEM project.

Results

We successfully transformed hundreds of individual plants, resulting in the first expression of chromoproteins in Marchantia, and probably the first expression of chromoproteins in any plant. We successfully built an arduino-controlled growth chamber, characterised an enzyme new to iGEM and amended the community's knowledge of an existing registry entry. A known Marchantia promoter was also added to the registry, along with 27 candidate promoters from the Marchantiagenome. They are part of a Marchantia starter kit part collection that also includes terminators, direction sequences, etc. Finally, we submitted an RFC with collaboration of two other iGEM teams, establishing a unified Type IIS based grammar for plant synthetic biologist: PlantSyntax. Click here for more result details, and here for our executive summary.

Our team

We are 9 Cambridge science undergraduates from various backgrounds and with all kinds of fascinating and curious interests. Click here to learn more about the team.

Retrieved from "http://2014.igem.org/Team:Cambridge-JIC"