Team:Goettingen/achievements

From 2014.igem.org

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<h1>Our achievements</h1>
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We have achieved the following 5 goals:<br /><br />
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☞ Register for iGEM, have a great summer, and attend the Giant Jamboree.<br />
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☞ Create a team wiki sharing background information, context, inspirations and goals for the project, and documentation of our process and outcomes.<br />
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<tr><td width="150" style="text-align:left;">Team:</td><td style="text-align:left;">Goettingen</td><td rowspan="5"><a href="https://2014.igem.org/Tracks/Health_Medicine"><img src="https://static.igem.org/mediawiki/2014/9/90/Goettingen_H%26M_logo.jpg" width="180"></a></td></tr>
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☞ Present a poster and talk at the Giant Jamboree.<br />
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<tr><td style="text-align:left;">iGEM Year:</td><td style="text-align:left;">2014</td></tr>
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☞ Demonstrate the use of art and design for thoughtful, critical investigation of the current and future implications of synthetic biology.<br />
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<tr><td style="text-align:left;">Judging:</td><td style="text-align:left;"><a href="https://igem.org/2014_Judging_Form?id=1430">Judging forms</a></td></tr>
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☞ Demonstrate the active engagement of engineers, scientists, members of the public, and other stakeholders as part of our project, during the initiation, development, presentation, and documentation our project.<br /><br /><br />
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<tr><td style="text-align:left;">Track:</td><td style="text-align:left;">Health & Medicine</td></tr>
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<tr><td style="text-align:left;">Project Name:</td><td style="text-align:left;">A small change for man, a giant pain for germkind.</td></tr>
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<tr><td style="text-align:left; vertical-align:top;">Project Abstract:</td><td style="text-align:left;"colspan="2">Our aim is to develop a diagnostic technique capable of detecting the presence of fungal pathogens in a sample collected from a patient. Briefly, our approach is as follows. Through a yeast two-hybrid assay we will select a set of peptides that show affinity towards surface proteins from different fungi (<i>Aspergillus nidulans, A. fumigatus, Candida albicans</i> and <i>C. glabrata</i>). After confirming the interaction between the surface proteins and a given peptide, we intend to attach a molecule to the peptide marker. In our project, this molecule will be a fluorescent protein, but in principle can also be an immune system activator which is then recognized by the immune cells or other chemical moiety that adds novel functionalities or increases the peptide stability.</td></tr>
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We have also achieved these 3 goals:<br /><br />
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☞ Create a short film about or as part of your project. This video has been sent to the committee and iGEM HQ.<br />
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☞ Design and execute a workshop or event for a group of people outside of our team.<br />
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<center><h1>Our achievements</h1></center><br />
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☞ Produce an installation or experiment (does not need to be biological) and document it or recreate it at iGEM. <br /><br /><br />
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1. <a href="https://2014.igem.org/Team:Goettingen/notebook_wetlab#week22" target="1">Identify a group of peptides able to interact with specific cell wall proteins from different fungi, by means of yeast two-hybrid assays.</a><br /><br />
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2. <a href="https://2014.igem.org/Team:Goettingen/notebook_wetlab#week23" target="1">Perform in vivo experiments to demonstrate and ensure on one hand, that the binding of the peptide is being to the cell wall protein, and on the other hand, that this binding is being to a specific fungi strain.</a><br /><br />
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<br />In addition to these achieved the following tasks:<br /><br />
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3. <a href="https://2014.igem.org/Team:Goettingen/notebook_wetlab#week19" target="1">Attach a marker molecule to the peptide in order to simplify its visualization using fluorescent microscopy.</a><br /><br />
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☞ Provoke us to think about synthetic biology and its implications in a new and novel way. We are looking for teams to break new ground and surprise us!<br />
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4. <a href="https://2014.igem.org/Team:Goettingen/notebook_wetlab/biobricks" target="1">Develop new standard Biobrick.</a><br /><br />
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☞ Collaborate directly with an iGEM team in another track.<br />
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5. <a href="https://2014.igem.org/Team:Goettingen target="1">Develop our team Wiki which represents all the dimensions of our project, and establish it as one of the main tools to inform people all over the world about our vision and accomplishments.<br /><br />
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☞ Design and document on the Registry of Standard Biological Parts at least one new standard BioBrick Part (teams working with biological materials must adhere to all laboratory safety requirements maintained by iGEM).<br />
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6. <a href="http://www.youtube.com/channel/UCmdyv-J42xCtx95RkOLp41A" target="1">Establish our own youtube channel, in which the videos show an introduction towards the team and simplify the techniques used in the lab.</a><br /><br />
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☞ iGEM projects involve important questions beyond the bench, for example relating to (but not limited to) ethics, sustainability, social justice, safety, security, or intellectual property rights. Describe an approach that your team used to address at least one of these questions. Evaluate your approach, including whether it allowed you to answer your question(s), how it influenced the team’s scientific project, and how it might be adapted for others to use (within and beyond iGEM). We encourage thoughtful and creative approaches, and those that draw on past Policy & Practice (formerly Human Practices) activities.<br /><br /><br />
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7. <a href="https://2014.igem.org/Team:Goettingen/outreach_overview" target="1">Be in contact with other iGEM teams.</a><br /><br />
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8. <a href="https://2014.igem.org/Team:Goettingen/outreach_human_practices" target="1">Make our community aware of iGEM, Synthetic Biology and our project through presentations, social media, press contact and other activities.</a> <br /> <br />
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<div id="footerbanner"><a href="https://2014.igem.org/Team:Goettingen/team_sponsors"><img src="https://static.igem.org/mediawiki/2014/7/7a/Goettingen_footer_banner.png" /></a></div>
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Latest revision as of 00:21, 18 October 2014


Team:Goettingen
iGEM Year:2014
Judging:Judging forms
Track:Health & Medicine
Project Name:A small change for man, a giant pain for germkind.
Project Abstract:Our aim is to develop a diagnostic technique capable of detecting the presence of fungal pathogens in a sample collected from a patient. Briefly, our approach is as follows. Through a yeast two-hybrid assay we will select a set of peptides that show affinity towards surface proteins from different fungi (Aspergillus nidulans, A. fumigatus, Candida albicans and C. glabrata). After confirming the interaction between the surface proteins and a given peptide, we intend to attach a molecule to the peptide marker. In our project, this molecule will be a fluorescent protein, but in principle can also be an immune system activator which is then recognized by the immune cells or other chemical moiety that adds novel functionalities or increases the peptide stability.


Our achievements


1. Identify a group of peptides able to interact with specific cell wall proteins from different fungi, by means of yeast two-hybrid assays.

2. Perform in vivo experiments to demonstrate and ensure on one hand, that the binding of the peptide is being to the cell wall protein, and on the other hand, that this binding is being to a specific fungi strain.

3. Attach a marker molecule to the peptide in order to simplify its visualization using fluorescent microscopy.

4. Develop new standard Biobrick.

5. Develop our team Wiki which represents all the dimensions of our project, and establish it as one of the main tools to inform people all over the world about our vision and accomplishments.

6. Establish our own youtube channel, in which the videos show an introduction towards the team and simplify the techniques used in the lab.

7. Be in contact with other iGEM teams.

8. Make our community aware of iGEM, Synthetic Biology and our project through presentations, social media, press contact and other activities.

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