Team:LIKA-CESAR-Brasil

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  <td height="150px" align="center" style=""><p style="color:#E7E7E7">&nbsp;</p></td>
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  <td height="150px" align="center" style=""><strong>WELCOME TO iGEM 2014! </strong>
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     <p>Thank you for your visit! We are under construction. <br>
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    <p style="color:#E7E7E7"> <a href="https://2014.igem.org/wiki/index.php?title=Team:LIKA-CESAR-Brasil&action=edit"style="color:#F36C1D"> Click here  to edit this page!</a></p></td>
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  <p><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil"style="color: #FFFFFF; border-color: #F36C1D;"><strong>Home</strong></a> </p></td>
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  <strong><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Team"style="color: #FFFFFF"> Team </a> </strong></td>
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  <strong><a href="https://igem.org/Team.cgi?year=2014&team_name=LIKA-CESAR-Brasil"style="color: #FFFFFF"> Official Team Profile </a></strong></td>
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  <strong><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Modeling"style="color: #FFFFFF;"> Modeling</a></strong></td>
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  <strong><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Notebook"style="color: #FFFFFF;"> Notebook</a></strong></td>
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  <strong><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Safety"style="color: #FFFFFF"> Safety </a></strong></td>
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  <strong><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Attributions"style="color: #FFFFFF;"> Attributions </a></strong></td>
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<td align ="center"> <strong><a href="https://2014.igem.org/Main_Page"> <img src="https://static.igem.org/mediawiki/igem.org/6/60/Igemlogo_300px.png" width="55"></a> </strong></td>
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    <h2>Project Description</h2>
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    <p style="font-size:14px">The LIKA-CESAR BRAZIL proposes the development of a <strong>biosensor</strong> for the detection of <strong>breast cancer</strong> with the help of robotics. The idea is to build a robotic system linked to genetic engineering capable of processing and prepare small samples of blood in an automated manner. For this our team, will generate useful BioBriks records and parts for possible future insertions in the plates. This system will be coupled to biosensors capable of detecting breast cancer in its earliest stage, where the chances of the patient having an accurate diagnosis and treatment guidance are very high.  The automation of the entire process, together with the creation of a specific biosensor for breast cancer, will result in a future decrease in deaths from the disease, due to a more rapid and effective treatment.</p>
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  <p> Please be sure to keep these links, your audience will want to find your: </p>
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  <!-- Links to other team pages -->
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  <ul>
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  <li><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil">Home</a> </li>
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  <li><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Team">Team</a> </li>
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  <li><a href="https://igem.org/Team.cgi?year=2013&team_name=LIKA-CESAR-Brasil">Official Team Profile</a> </li>
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  <li><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Project">Project</a> </li>
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  <li><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Parts">Parts</a> </li>
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  <li><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Modeling">Modeling</a> </li>
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  <li><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Notebook">Notebook</a> </li>
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  <li><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Safety">Safety</a> </li>
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  <li><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Attributions">Attributions</a> </li>
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  <p>There are a few wiki requirements teams must follow:</p>
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  <li>All pages must be created under the team’s name space.</li>
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  <li>As part of your documentation, keep the links from the menu to the left. </li>
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  <li>Do not use flash in wiki code. </li>
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   <td ><strong>Tips </strong></td>
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    <div class="navbar navbar-inverse navbar-fixed-top" role="navigation">
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<td width="48%" height="460" align="left" valign="top">  
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      <div class="container">
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<p>We are currently working on providing teams with some easy to use design templates.
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    <header>
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<br> In the meantime you can also view other team wikis for inspiration! Here are some very good examples</p>
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<li> <a href="https://2013.igem.org/Team:SDU-Denmark/"> 2013 SDU Denmark </a> </li>
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<li> <a href="https://2013.igem.org/Team:SYSU-China">2013 SYSU China</a> </li>
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<li> <a href="https://2013.igem.org/Team:Shenzhen_BGIC_ATCG"> 2013 Shenxhen BGIG ATCG </a></li>
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<li> <a href="https://2013.igem.org/Team:Colombia_Uniandes">2013 Colombia Unianades </a></li>
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<li> <a href="https://2013.igem.org/Team:Lethbridge">2013 Lethbridge</a></li>
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      <a class="navbar-brand" href="https://2014.igem.org/Team:LIKA-CESAR-Brasil"><img src="https://static.igem.org/mediawiki/2014/5/55/Marca.png" alt="Marca LIKA"></a>
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<p>For a full wiki list, you can visit <a href="https://igem.org/Team_Wikis?year=2013">iGEM 2013 web sites </a> and <a href="https://igem.org/Team_Wikis?year=2012">iGEM 2012 web sites</a>  lists. </p>
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        <li><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil">HOME</a></li>
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                  <li><a href="https://2014.igem.org/Team:LIKA-CESAR-Brasil/Partnerships">Partnerships</a></li>
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        <h2>Synthetic Biology and Robotics - The Integration that can Save Lives</h2>
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        <p>The LIKA-CESAR BRASIL proposes the development of a biosensor for the detection of breast cancer with the help of synthetic biology and robotics. The idea was to build a robotic system linked to genetic engineering capable of processing and prepare small samples of blood in an automated manner.</p>
 +
        <p>For this our team, created the Coli Alert for the BreastBotSensor. This system is one robot to DNA/RNA extraction coupled by an electrochemical biosensor and linked to one quality control, the ColiAlert, responsible to confirm the process of nucleic acid extraction.</p>
 +
        <p>The team believes that the best way to solve problems is joining technologies. For this, we think that synthetic biology should go hand in hand with robotics and information technology. Then our project was to join the synthetic biology with the robots, aiming to fight against to the one of biggest health problems: The Breast Cancer.</p>
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                            <source src="https://static.igem.org/mediawiki/2014/5/5b/CESAR_%26_LIKA_-_Against_breast_cancer.ogg" type='video/ogg; codecs="theora, vorbis"'/>
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                        </video>
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<td width="48%" align="left" valign="top">  
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          <h2>Bot</h2>
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          <p>The bot was built by Team LIKA-CESAR-Brasil. It is a robot responsible for automating the extraction of nucleic acids from blood. Most of the pieces were created from a 3D printer to cheapen the system.  It consists of a eletric syringe, a robotic arm and a centrifuge together to perform the entire procedure. Nucleic acids extracted by Bot, will be sent for analysis in BreastSensor.</p>
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          <h2>ColiAlert</h2>
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          <p>The team also made an alert system of cell lysis called ColiAlert . This system was created to be the quality control of Bot. It is a genetically engineered bacteria able to alert the process of cell lysis by color change. Under normal conditions the ColiAlert is pink, but after cell lysis, it becomes yellow. After going through this system of quality control, the sample is ready to proceed to BreastSensor.</p>
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          <h2>BreastSensor</h2>
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          <p>To finalize the project, the team created the BreastSensot. It is an electrochemical DNA biosensor capable of recognizing a biomarker for breast cancer. This  biomarker is a  which has a high expression in the early stage of this type of cancer.The biosensor constructed has the ability to perform an early diagnosis of a patient with breast cancer.</p>
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Latest revision as of 02:45, 18 October 2014

LIKA | CESAR

Synthetic Biology and Robotics - The Integration that can Save Lives

The LIKA-CESAR BRASIL proposes the development of a biosensor for the detection of breast cancer with the help of synthetic biology and robotics. The idea was to build a robotic system linked to genetic engineering capable of processing and prepare small samples of blood in an automated manner.

For this our team, created the Coli Alert for the BreastBotSensor. This system is one robot to DNA/RNA extraction coupled by an electrochemical biosensor and linked to one quality control, the ColiAlert, responsible to confirm the process of nucleic acid extraction.

The team believes that the best way to solve problems is joining technologies. For this, we think that synthetic biology should go hand in hand with robotics and information technology. Then our project was to join the synthetic biology with the robots, aiming to fight against to the one of biggest health problems: The Breast Cancer.

Bot

The bot was built by Team LIKA-CESAR-Brasil. It is a robot responsible for automating the extraction of nucleic acids from blood. Most of the pieces were created from a 3D printer to cheapen the system. It consists of a eletric syringe, a robotic arm and a centrifuge together to perform the entire procedure. Nucleic acids extracted by Bot, will be sent for analysis in BreastSensor.

ColiAlert

The team also made an alert system of cell lysis called ColiAlert . This system was created to be the quality control of Bot. It is a genetically engineered bacteria able to alert the process of cell lysis by color change. Under normal conditions the ColiAlert is pink, but after cell lysis, it becomes yellow. After going through this system of quality control, the sample is ready to proceed to BreastSensor.

BreastSensor

To finalize the project, the team created the BreastSensot. It is an electrochemical DNA biosensor capable of recognizing a biomarker for breast cancer. This biomarker is a which has a high expression in the early stage of this type of cancer.The biosensor constructed has the ability to perform an early diagnosis of a patient with breast cancer.

Marca LIKA Marca CESAR

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