Team:UCSF UCB

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<h1 >WELCOME TO iGEM 2014! </h1>
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<p>Your team has been approved and you are ready to start the iGEM season!
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<br>On this page you can document your project, introduce your team members, document your progress <br> and share your iGEM experience with the rest of the world! </p>
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<p style="color:#E7E7E7"> <a href="https://2014.igem.org/wiki/index.php?title=Team:UCSF_UCB&action=edit"style="color:#FFFFFF"> Click here  to edit this page!</a> </p>
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<a href="https://2014.igem.org/Team:UCSF_UCB"style="color:#000000">Home </a> </td>
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<a href="https://2014.igem.org/Team:UCSF_UCB/Team"style="color:#000000"> Team </a> </td>
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<a href="https://igem.org/Team.cgi?year=2014&team_name=UCSF_UCB"style="color:#000000"> Official Team Profile </a></td>
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<a href="https://2014.igem.org/Team:UCSF_UCB/Project"style="color:#000000"> Project</a></td>
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<a href="https://2014.igem.org/Team:UCSF_UCB/Parts"style="color:#000000"> Parts</a></td>
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<a href="https://2014.igem.org/Team:UCSF_UCB/Modeling"style="color:#000000"> Modeling</a></td>
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<a href="https://2014.igem.org/Team:UCSF_UCB/Attributions"style="color:#000000"> Attributions </a></td>
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<td align ="center"> <a href="https://2014.igem.org/Main_Page"> <img src="https://static.igem.org/mediawiki/igem.org/6/60/Igemlogo_300px.png" width="55px"></a> </td>
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<tr><td colspan="3"> <h3> Abstract </h3></td></tr>
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Cells in a local population have a wide range of responses to a given stimulus. This noisiness may be due to differences in extracelluar environment, or intracellular molecular makeup. Yet these cells often need to coordinate and respond in a concerted way. For example, all T cells in a lymph node respond to an antigen, yet only those with a strong initial reaction proliferate and effect an immune response. In another example, V. fischeri sense local population levels and require quorum to express bioluminesence. Our project seeks to understand the complex intercellular interactions that must happen to produce such a specific community phenotype.
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<em>Our goal is to investigate how a group of cells coordinate their behaviors using extracellular signaling by engineering essential coordination motifs. </em>
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Latest revision as of 07:05, 17 October 2014

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Intercellular Coordination Through Community Signaling

Cells in a local population have a wide range of responses to a given stimulus. This noisiness may be due to differences in extracelluar environment or intracellular molecular makeup. Yet these cells often need to coordinate and respond in a concerted way. Our project seeks to understand the complex intercellular interactions that must happen to produce such a specific community phenotype.

Our goal is to create a synthetic framework that uses cellular communities to model collective behaviors emergent from individual autonomous rules.

Explore Our Project

Judging

Judges! Check out our judging section for a compiled list of the iGEM requirements that we have fulfilled. This section also contains information about the safety and implications of our project.

Visit Our Judging Page

Team Members and Mentors

Discover the people behind the parts and models. See our faces and read our bios. Contact us! We love feedback.

Meet Our Team
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