Team:Sheffield

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<div class="caption bounceInDown" data-wow-delay="0.4s">
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          <h1>A SYNTHETIC BIOLOGY SOLUTION FOR<br>AN EVERYDAY PROBLEM</h1>
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<p>We have engineered E. coli to secrete fat and hair degrading enzymes to solve the problem of accumulations in sewer networks</p>
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          <div class="slide-btns">
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          <a class="startnow" href="https://2014.igem.org/Team:Sheffield/Project">VIEW MORE</a>
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          <img src="https://static.igem.org/mediawiki/2014/4/41/SheffieldHome7.png" alt="">
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          <div class="caption">
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          <h1>Manufacturing a workable solution</h1>
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<p>We have created an innovative undersink bioreactor unit to degrade fat waste before it has chance to form <em>fatbergs</em></p>
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          <div class="slide-btns">
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          <a class="startnow" href="https://2014.igem.org/Team:Sheffield/modelling">VIEW MORE</a>
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          <div class="caption">
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          <h1>NOTIONS OF RESPONSIBILTY</h1>
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<p>Who should be responsible for the maintenance of drains? Is it the responsibility of synthetic biologists to step in?</p>
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          <div class="slide-btns">
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          <a class="startnow" href="https://2014.igem.org/Team:Sheffield/Notions">VIEW MORE</a>
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<h4><b>The Fatberglar: A small scale, semi-continuous bioreactor for the controlled release of FOG degrading enzymes</b></h4>
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<h5>Fats, oils and greases (FOGs) enter the national sewage system and accumulate, leading to blocked pipes, nicknamed “fatbergs”. There are currently over 200,000 major UK sewage blockages a year, of which 75% are caused by FOGs; tackling these blockages costs water companies millions of pounds every month.
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<h1 >WELCOME TO iGEM 2014! </h1>
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<p>Your team has been approved and you are ready to start the iGEM season!
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<br>On this page you can document your project, introduce your team members, document your progress <br> and share your iGEM experience with the rest of the world! </p>
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<p style="color:#E7E7E7"> <a href="https://2014.igem.org/wiki/index.php?title=Team:Sheffield&action=edit"style="color:#FFFFFF"> Click here  to edit this page!</a> </p>
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The biological project work focused on development of constructs that produce lipase and keratinase enzymes to degrade FOGs and hair. These constructs are designed to sit within a small, under-sink bioreactor that will produce and feed them into the waste system as the sink is drained.
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To shape the approach, there has been significant interaction with industry experts and the public to gauge where the responsibility lies for the maintenance of the damaged drains; awareness of synthetic biology has been raised alongside this. A novel method of characterising the policy and practices component of the iGEM competition is also presented here.</h5>
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<img src="https://static.igem.org/mediawiki/2014/4/4c/SheffieldLogo6.png" width="200px">&nbsp;&nbsp;
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<img src="https://static.igem.org/mediawiki/2014/0/0d/SheffieldLogo2.png" width="200px">&nbsp;&nbsp;
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<img src="https://static.igem.org/mediawiki/2014/a/a6/SheffieldLogo9.png" width="200px">&nbsp;&nbsp;<br>
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&nbsp;&nbsp;<img src="https://static.igem.org/mediawiki/2014/8/85/SheffieldLogo11.jpg" width="200px">&nbsp;&nbsp;
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<img src="https://static.igem.org/mediawiki/2014/4/4e/SheffieldLogo3.png" width="200px">&nbsp;&nbsp;
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<a href="https://2014.igem.org/Team:Sheffield"style="color:#000000">Home </a> </td>
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<img src="https://static.igem.org/mediawiki/2014/1/19/SheffieldLogo5.png" width="200px">
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<a href="https://2014.igem.org/Team:Sheffield/Team"style="color:#000000"> Team </a> </td>
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<a href="https://igem.org/Team.cgi?year=2014&team_name=Sheffield"style="color:#000000"> Official Team Profile </a></td>
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<a href="https://2014.igem.org/Team:Sheffield/Project"style="color:#000000"> Project</a></td>
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<a href="https://2014.igem.org/Team:Sheffield/Parts"style="color:#000000"> Parts</a></td>
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<a href="https://2014.igem.org/Team:Sheffield/Modeling"style="color:#000000"> Modeling</a></td>
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<a href="https://2014.igem.org/Team:Sheffield/Notebook"style="color:#000000"> Notebook</a></td>
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<a href="https://2014.igem.org/Team:Sheffield/Attributions"style="color:#000000"> Attributions </a></td>
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<td align ="center"> <a href="https://2014.igem.org/Main_Page"> <img src="https://static.igem.org/mediawiki/igem.org/6/60/Igemlogo_300px.png" width="55px"></a> </td>
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<p> Please be sure to keep these links, your audience will want to find your: </p>
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<li><a href="https://2014.igem.org/Team:Sheffield">Home</a> </li>
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<li><a href="https://2014.igem.org/Team:Sheffield/Team">Team</a> </li>
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<li><a href="https://igem.org/Team.cgi?year=2013&team_name=Sheffield">Official Team Profile</a> </li>
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<li><a href="https://2014.igem.org/Team:Sheffield/Project">Project</a> </li>
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<li><a href="https://2014.igem.org/Team:Sheffield/Parts">Parts</a> </li>
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<li><a href="https://2014.igem.org/Team:Sheffield/Modeling">Modeling</a> </li>
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<li><a href="https://2014.igem.org/Team:Sheffield/Notebook">Notebook</a> </li>
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<li><a href="https://2014.igem.org/Team:Sheffield/Safety">Safety</a> </li>
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<li>As part of your documentation, keep the links from the menu to the left. </li>
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<li>The <a href="https://static.igem.org/mediawiki/igem.org/6/60/Igemlogo_300px.png"> iGEM logo </a> should be placed on the upper part of every page and should link to <a href="https://2014.igem.org/Main_Page">2014.igem.org</a>.</li>
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<p>We are currently working on providing teams with some easy to use design templates.
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<br> In the meantime you can also view other team wikis for inspiration! Here are some very good examples</p>
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<li> <a href="https://2013.igem.org/Team:SDU-Denmark/"> 2013 SDU Denmark </a> </li>
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<li> <a href="https://2013.igem.org/Team:SYSU-China">2013 SYSU China</a> </li>
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<li> <a href="https://2013.igem.org/Team:Shenzhen_BGIC_ATCG"> 2013 Shenxhen BGIG ATCG </a></li>
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<li> <a href="https://2013.igem.org/Team:Colombia_Uniandes">2013 Colombia Unianades </a></li>
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<li> <a href="https://2013.igem.org/Team:Lethbridge">2013 Lethbridge</a></li>
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<p>For a full wiki list, you can visit <a href="https://igem.org/Team_Wikis?year=2013">iGEM 2013 web sites </a> and <a href="https://igem.org/Team_Wikis?year=2012">iGEM 2012 web sites</a>  lists. </p>
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<p>This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started: </p>
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<li>State your accomplishments! Tell people what you have achieved from the start. </li>
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<li>You have a global audience! Consider the different backgrounds that your users come from.</li>
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<li>Make sure information is easy to find; nothing should be more than 3 clicks away.  </li>
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<li>Avoid using very small fonts and low contrast colors; information should be easy to read.  </li>
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<li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="">iGEM 2013 calendar</a> </li>
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<li>Have lots of fun! </li>
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Latest revision as of 03:44, 18 October 2014




  • A SYNTHETIC BIOLOGY SOLUTION FOR
    AN EVERYDAY PROBLEM

    We have engineered E. coli to secrete fat and hair degrading enzymes to solve the problem of accumulations in sewer networks

  • Manufacturing a workable solution

    We have created an innovative undersink bioreactor unit to degrade fat waste before it has chance to form fatbergs

  • NOTIONS OF RESPONSIBILTY

    Who should be responsible for the maintenance of drains? Is it the responsibility of synthetic biologists to step in?

The Fatberglar: A small scale, semi-continuous bioreactor for the controlled release of FOG degrading enzymes

Fats, oils and greases (FOGs) enter the national sewage system and accumulate, leading to blocked pipes, nicknamed “fatbergs”. There are currently over 200,000 major UK sewage blockages a year, of which 75% are caused by FOGs; tackling these blockages costs water companies millions of pounds every month.

The biological project work focused on development of constructs that produce lipase and keratinase enzymes to degrade FOGs and hair. These constructs are designed to sit within a small, under-sink bioreactor that will produce and feed them into the waste system as the sink is drained.

To shape the approach, there has been significant interaction with industry experts and the public to gauge where the responsibility lies for the maintenance of the damaged drains; awareness of synthetic biology has been raised alongside this. A novel method of characterising the policy and practices component of the iGEM competition is also presented here.