Template:Team:LMU-Munich/tour

Welcome to our Wiki! I'm BaKillus, the pathogen-hunting microbe, and I'll guide you on this tour through our project. If you want to learn more about a specific step, you can simply close the tour and come back to it anytime you like. So let's start!

<div class="tour-button-close"><img src="https://static.igem.org/mediawiki/2014/a/a0/LMU14-hidetour.png" /></div>

<a href="https://2014.igem.org/Team:LMU-Munich/Project/Problem"><img src="https://static.igem.org/mediawiki/2014/0/08/LMU14_simpleArrowRight.png" /> </a>

== What's the problem? ==

First of all, what am I doing here? The problem is, pathogenic bacteria all around the world are becoming more and more  resistant against antimicrobial drugs. One major reason for the trend is the inappropriate use of drugs. With my BaKillus super powers, I want to reduce this misuse and thus do my part to save global health.

<a href="https://2014.igem.org/Team:LMU-Munich"><img src="https://static.igem.org/mediawiki/2014/8/83/LMU14_simpleArrowLeft.png" /> </a>

<div class="tour-button-close"><img src="https://static.igem.org/mediawiki/2014/a/a0/LMU14-hidetour.png" /></div>

<a href="https://2014.igem.org/Team:LMU-Munich/Project/Bakillus#sensing"><img src="https://static.igem.org/mediawiki/2014/0/08/LMU14_simpleArrowRight.png" /> </a>

 

== Sensing of pathogens ==

To combat the pathogenic bacteria, I simply eavesdrop on their communication. Bacteria talk with each other via quorum sensing systems, which I use to detect them and trigger my responses.  

<a href="https://2014.igem.org/Team:LMU-Munich/Project/Problem"><img src="https://static.igem.org/mediawiki/2014/8/83/LMU14_simpleArrowLeft.png" /> </a>

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<a href="https://2014.igem.org/Team:LMU-Munich/Project/Bakillus#adhesion"><img src="https://static.igem.org/mediawiki/2014/0/08/LMU14_simpleArrowRight.png" /> </a>

 

== Adhesion ==

The more specific and effective I can use my powers, the lower the danger is of provoking new resistance development. So I catch pathogens whenever I get hold of them and stick to them until my work is done.

<a href="https://2014.igem.org/Team:LMU-Munich/Project/Bakillus#sensing"><img src="https://static.igem.org/mediawiki/2014/8/83/LMU14_simpleArrowLeft.png" /> </a>

<div class="tour-button-close"><img src="https://static.igem.org/mediawiki/2014/a/a0/LMU14-hidetour.png" /></div>

<a href="https://2014.igem.org/Team:LMU-Munich/Project/Bakillus#killing"><img src="https://static.igem.org/mediawiki/2014/0/08/LMU14_simpleArrowRight.png" /> </a>

 

== Killing ==

Talking about my work - killing pathogens is finally what I am made for. In response to quorum sensing molecules of the pathogens, I export a range of antimicrobial substances leading to dissipation of biofilms and the killing of the targeted bacteria.  

<a href="https://2014.igem.org/Team:LMU-Munich/Project/Bakillus#adhesion"><img src="https://static.igem.org/mediawiki/2014/8/83/LMU14_simpleArrowLeft.png" /> </a>

<div class="tour-button-close"><img src="https://static.igem.org/mediawiki/2014/a/a0/LMU14-hidetour.png" /></div>

<a href="https://2014.igem.org/Team:LMU-Munich/Project/Bakillus#suicide"><img src="https://static.igem.org/mediawiki/2014/0/08/LMU14_simpleArrowRight.png" /> </a>

 

== Suicide switch ==

When the job is done and all the bad guys are finished, you don't need a super hero anymore. So after fulfilling my work I say goodbye to the world by activating my suicide switch.  

<a href="https://2014.igem.org/Team:LMU-Munich/Project/Bakillus#killing"><img src="https://static.igem.org/mediawiki/2014/8/83/LMU14_simpleArrowLeft.png" /> </a>

<div class="tour-button-close"><img src="https://static.igem.org/mediawiki/2014/a/a0/LMU14-hidetour.png" /></div>

<a href="https://2014.igem.org/Team:LMU-Munich/Application"><img src="https://static.igem.org/mediawiki/2014/0/08/LMU14_simpleArrowRight.png" /> </a>

 

== Application ==

Of course I'm not only a fictional hero, but a very real one. In two different prototypes, I could be used for diagnosis or treatment of pathogen-caused diseases. However, there is still a whole lot of regulational and economical questions that have to be answered before.  

<a href="https://2014.igem.org/Team:LMU-Munich/Project/Bakillus#suicide"><img src="https://static.igem.org/mediawiki/2014/8/83/LMU14_simpleArrowLeft.png" /> </a>

<div class="tour-button-close"><img src="https://static.igem.org/mediawiki/2014/a/a0/LMU14-hidetour.png" /></div>

<a href="https://2014.igem.org/Team:LMU-Munich"><img src="https://static.igem.org/mediawiki/2014/0/08/LMU14_simpleArrowRight.png" /> </a>

 

== See you! ==

So now you know my short story - and it is time for me to return to my fight for a safer world. Feel free to take a closer look on my [https://2014.igem.org/Team:LMU-Munich/Project/Bakillus super powers], the [https://2014.igem.org/Team:LMU-Munich/Notebook/Timeline process of my development] or the plans for a [https://2014.igem.org/Team:LMU-Munich/Application medical application].

<a href="https://2014.igem.org/Team:LMU-Munich/Application"><img src="https://static.igem.org/mediawiki/2014/8/83/LMU14_simpleArrowLeft.png" /> </a>

<div class="tour-button-close"><img src="https://static.igem.org/mediawiki/2014/a/a0/LMU14-hidetour.png" /></div>