Team:NTU Taida/M1
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+ | In modeling , we focus on the interpretation of experimental data and predict the outcomes with different initial conditions, which means different initial concentration of fatty acid.</b></font> | ||
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<b>1. Prediction of fundamentals of exfoliation circuit</p></b> | <b>1. Prediction of fundamentals of exfoliation circuit</p></b> | ||
In our circuit design of exfoliation, one of core concept is using lambda repressor(CI) to regulate the gene expression of keratinase. We have written a script in matlab to simulate this system repression according to [9]. In our simulation, we assume that when pfdba promoter is working, it will work as constitutive promoter,and the mathematical descriptions of the model are:</p> | In our circuit design of exfoliation, one of core concept is using lambda repressor(CI) to regulate the gene expression of keratinase. We have written a script in matlab to simulate this system repression according to [9]. In our simulation, we assume that when pfdba promoter is working, it will work as constitutive promoter,and the mathematical descriptions of the model are:</p> | ||
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The model consists of basal expression(α0Y),protein synthesis(αC,αY),repressor binding(βC),protein decay(γC,γY) and repressor cooperativity(ηC) for CI(C) and keratinase(Y).Following figure 1 shows the result of simulation.</p> | The model consists of basal expression(α0Y),protein synthesis(αC,αY),repressor binding(βC),protein decay(γC,γY) and repressor cooperativity(ηC) for CI(C) and keratinase(Y).Following figure 1 shows the result of simulation.</p> | ||
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<center><u>Fig 1 simulation prediction of exfoliation circuit</u></center> | <center><u>Fig 1 simulation prediction of exfoliation circuit</u></center> | ||
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Latest revision as of 01:05, 18 October 2014