Team:PoznanBioInf/Project

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<h1 >WELCOME TO iGEM 2014! </h1>
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<p>Your team has been approved and you are ready to start the iGEM season!
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<br>On this page you can document your project, introduce your team members, document your progress <br> and share your iGEM experience with the rest of the world! </p>
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<p style="color:#E7E7E7"> <a href="https://2014.igem.org/wiki/index.php?title=Team:PoznanBioInf/Project&action=edit"style="color:#FFFFFF"> Click here  to edit this page!</a> </p>
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    <li><a href="https://2014.igem.org/Team:PoznanSoft/Project">PROJECT</a></li>
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    <li><a href="https://2014.igem.org/Team:PoznanSoft/Notebook">NOTEBOOK</a></li>
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    <li><a href="https://2014.igem.org/Team:PoznanSoft/Parts">PARTS</a></li>
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    <li style="padding-top: none; width: 140px; padding: 10px 5px; margin-top: 50px; border-top:none;"><a href="https://2014.igem.org/Team:PoznanBioInf" style = "padding: 0 0;"><img src="https://static.igem.org/mediawiki/2014/9/96/PoznanBioInf_rec.png" style = "width: 130px;" /></a></li>
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    <li><a href="https://2014.igem.org/Team:PoznanSoft/Team">TEAM</a></li>
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    <li><a href="https://2014.igem.org/Team:PoznanSoft/Attributions"">ATTRIB'S</a></li>
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    <li><a href="https://2014.igem.org/Team:PoznanSoft/Attributions">CONTACT</a></li>
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<a href="https://2014.igem.org/Team:PoznanBioInf"style="color:#000000">Home </a> </td>
 
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<a href="https://2014.igem.org/Team:PoznanBioInf/Team"style="color:#000000"> Team </a> </td>
 
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<a href="https://igem.org/Team.cgi?year=2014&team_name=PoznanBioInf"style="color:#000000"> Official Team Profile </a></td>
 
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<a href="https://2014.igem.org/Team:PoznanBioInf/Project"style="color:#000000"> Project</a></td>
 
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<a href="https://2014.igem.org/Team:PoznanBioInf/Modeling"style="color:#000000"> Modeling</a></td>
 
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<a href="https://2014.igem.org/Team:PoznanBioInf/Notebook"style="color:#000000"> Notebook</a></td>
 
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<a href="https://2014.igem.org/Team:PoznanBioInf/Safety"style=" color:#000000"> Safety </a></td>
 
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<a href="https://2014.igem.org/Team:PoznanBioInf/Attributions"style="color:#000000"> Attributions </a></td>
 
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<td align = "center" width="500px"  height="400px" bgColor="#000000" style = "font-family: PTSans;"><img align = middle src="https://static.igem.org/mediawiki/2014/5/55/PoznanBioInf_LOGO.png" width="400px"></td>
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<p>Tell us more about your project.  Give us background.  Use this as the abstract of your project.  Be descriptive but concise (1-2 paragraphs) </p>
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<h3>References </h3>
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iGEM teams are encouraged to record references you use during the course of your research. They should be posted somewhere on your wiki so that judges and other visitors can see how you though about your project and what works inspired you. </p>
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<li>Overall project summary</li>
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<li>Project Details</li>
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<li>Materials and Methods</li>
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It's important for teams to describe all the creativity that goes into an iGEM project, along with all the great ideas your team will come up with over the course of your work.  
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It's also important to clearly describe your achievements so that judges will know what you tried to do and where you succeeded. Please write your project page such that what you achieved is easy to distinguish from what you attempted.
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<h3><font color="white" style="font-family: PTSans; font-size: 20px;">REColi: Signal amplification and formattable bacterial memory by DNA edition.</font>
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We have designed a synthetic digital device inspired by electronic circuits called multiplexers. Its 3-bit memory allows saving and processing binary inputs in E. coli. Induced expression of serine recombinases, capable of specific DNA editing, enables construction of biological analogues of transistors - transcriptors - and their use as elementary memory units called SR-latches. The fourth, strobe signal resets the system to its original state. We have shown that the system could efficiently store data about previous contact with inducing sugars across hundreds of generations. This memory unit offers high sensitivity in inducer detection and signal amplification, allowing cheap induction or further development and use as a trace contaminants sensor. Eight possible output combinations, reported as RGB fluorescent proteins, may also turn out to be useful for complex coexpression research.
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Latest revision as of 03:59, 18 October 2014

REColi: Signal amplification and formattable bacterial memory by DNA edition.

We have designed a synthetic digital device inspired by electronic circuits called multiplexers. Its 3-bit memory allows saving and processing binary inputs in E. coli. Induced expression of serine recombinases, capable of specific DNA editing, enables construction of biological analogues of transistors - transcriptors - and their use as elementary memory units called SR-latches. The fourth, strobe signal resets the system to its original state. We have shown that the system could efficiently store data about previous contact with inducing sugars across hundreds of generations. This memory unit offers high sensitivity in inducer detection and signal amplification, allowing cheap induction or further development and use as a trace contaminants sensor. Eight possible output combinations, reported as RGB fluorescent proteins, may also turn out to be useful for complex coexpression research.

Retrieved from "http://2014.igem.org/Team:PoznanBioInf/Project"