Team:ITB Indonesia/FutureSystem

From 2014.igem.org

(Difference between revisions)
 
(One intermediate revision not shown)
Line 1: Line 1:
-
<html>
 
-
<head>
 
-
<title></title>
 
-
<style>
 
-
body{
 
-
background-image: url(https://static.igem.org/mediawiki/2014/4/47/Itb-bg.jpg);
 
-
background-repeat: repeat;
 
-
}#logo-igem{width:160px;height:100px;position:absolute;right:28px;top:33px;background-color:orange;cursor:pointer;opacity:0.01}
 
-
 
-
 
-
#top-section{width:1010px;height:47px;background-color:#FFFFFF;}
 
-
 
-
#menubar{top:10px;padding-left:25px;padding-right:25px;}
 
-
 
-
#menubar ul li a{background-color:#FFFFFF;color:black;}
 
-
#menubar a:hover{text-decoration:underline;}
 
-
#menubar.left-menu.noprint{background-color:#FFFFFF;}
 
-
 
-
#menubar ul li:nth-child(1){background-color:#FFFFFF;color:black;}
 
-
#menubar ul li:nth-child(2){background-color:#FFFFFF;color:black;}
 
-
#menubar ul li:nth-child(3){background-color:#FFFFFF;color:black;}
 
-
#menubar ul li:nth-child(4){background-color:#FFFFFF;color:black;}
 
-
#menubar ul li:nth-child(5){background-color:#FFFFFF;color:black;}
 
-
#menubar ul li:nth-child(6){background-color:#FFFFFF;color:black;}
 
-
#menubar ul li:nth-child(7){visibility:hidden;}
 
-
 
-
#p-logo img{display:none;}
 
-
 
-
#search-controls{display:none;}
 
-
 
-
.firstHeading{display:none;}
 
-
#content{width:1000px;}
 
-
#footer-box{display:none;}
 
-
 
-
#putih{
 
-
width: 1000px;
 
-
margin: 0 auto;
 
-
background-color: #FFFFFF;
 
-
}
 
-
 
-
#center{
 
-
width: 960px;
 
-
margin: 0 auto;
 
-
}
 
-
 
-
 
-
/*****    Start Header    *****/
 
-
#logo{
 
-
width: 960px;
 
-
height: 100px;
 
-
background-image: url(https://static.igem.org/mediawiki/2014/3/3e/Itb-logo.jpg);
 
-
/*background-color: #FFFFAA;*/
 
-
/*position: absolute;
 
-
top: 0;*/
 
-
}
 
-
 
-
#header{
 
-
/*margin-top: 10px;*/
 
-
width: 960px;
 
-
height: 200px;
 
-
background-image: url(https://static.igem.org/mediawiki/2014/5/56/Itb-judul.jpg);
 
-
}
 
-
/*****    End Header    *****/
 
-
 
-
 
-
/*****    Start Nav    *****/
 
-
#blockNav{
 
-
width: 960px;
 
-
height: 48px;
 
-
background-color: #38AF89;
 
-
}
 
-
 
-
ul {
 
-
  text-align: left;
 
-
  display: inline;
 
-
  margin: 0;
 
-
  padding: 15px 4px 17px 0;
 
-
  list-style: none;
 
-
  /*-webkit-box-shadow: 0 0 5px rgba(0, 0, 0, 0.15);
 
-
  -moz-box-shadow: 0 0 5px rgba(0, 0, 0, 0.15);
 
-
  box-shadow: 0 0 5px rgba(0, 0, 0, 0.15);*/
 
-
}
 
-
ul li {
 
-
  font: bold 12px/18px sans-serif;
 
-
  /*font-family: source-code-pro, sans-serif;*/
 
-
  color: #FFFFFF;
 
-
  display: inline-block;
 
-
  margin-right: -4px;
 
-
  position: relative;
 
-
  padding: 15px 20px;
 
-
  background: #38AF89;
 
-
  cursor: pointer;
 
-
  -webkit-transition: all 0.2s;
 
-
  -moz-transition: all 0.2s;
 
-
  -ms-transition: all 0.2s;
 
-
  -o-transition: all 0.2s;
 
-
  transition: all 0.2s;
 
-
}
 
-
ul li:hover {
 
-
  background: #2E9876;
 
-
  color: #FFFFFF;
 
-
}
 
-
ul li ul {
 
-
  padding: 0;
 
-
  position: absolute;
 
-
  top: 48px;
 
-
  left: 0;
 
-
  width: 180px;
 
-
  -webkit-box-shadow: none;
 
-
  -moz-box-shadow: none;
 
-
  box-shadow: none;
 
-
  display: none;
 
-
  opacity: 0;
 
-
  visibility: hidden;
 
-
  -webkit-transiton: opacity 0.2s;
 
-
  -moz-transition: opacity 0.2s;
 
-
  -ms-transition: opacity 0.2s;
 
-
  -o-transition: opacity 0.2s;
 
-
  -transition: opacity 0.2s;
 
-
}
 
-
ul li ul li{
 
-
  background: #2E9876;
 
-
  display: block;
 
-
  color: #FFFFFF;
 
-
  text-shadow: 0 -1px 0 #000;
 
-
}
 
-
ul li ul li:hover { background: #4CB795; }
 
-
ul li:hover ul {
 
-
  display: block;
 
-
  opacity: 1;
 
-
  visibility: visible;
 
-
}
 
-
 
-
a:link {
 
-
    text-decoration: none;
 
-
    color: #FFFFFF;
 
-
}
 
-
 
-
a:visited {
 
-
    text-decoration: none;
 
-
    color: #FFFFFF;
 
-
}
 
-
/*****    End Nav    *****/
 
-
 
-
 
-
/*****    Start Content    *****/
 
-
iframe{
 
-
margin: 30px 0 30px 200px;
 
-
}
 
-
 
-
#line{
 
-
width: 960px;
 
-
height: 1px;
 
-
background-color: #BCBCB3;
 
-
}
 
-
/*****    End Content    *****/
 
-
 
-
/*****    Start Sponsor    *****/
 
-
#sponsor{
 
-
width: 960px;
 
-
height: 200px;
 
-
background-image: url(https://static.igem.org/mediawiki/2014/3/36/Itb-sponsor.jpg);
 
-
}
 
-
/*****    End Sponsor    *****/
 
-
 
-
 
-
</style>
 
-
<script src="//use.edgefonts.net/source-code-pro.js"></script>
 
-
</head>
 
-
<body>
 
-
<div id="putih"> <div id="logo-igem" onclick="window.location.href='https://2014.igem.org/'"></div>
 
-
<div id="center">
 
-
<div id="logo"></div>
 
-
 
-
<div id="header"></div>
 
-
 
-
<div id="blockNav">
 
-
<ul>
 
-
<li><a href="https://2014.igem.org/Team:ITB_Indonesia">HOME</a></li>
 
-
<li>TEAM
 
-
<ul>
 
-
<li><a href="https://igem.org/Team.cgi?id=1387" >OFFICIAL TEAM PROFILE</a></li>
 
-
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/Team">TEAM MEMBER</a></li>
 
-
</ul>
 
-
</li>
 
-
<li>PROJECT
 
-
<ul>
 
-
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/Project">OVERVIEW</a></li>
 
-
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/DegMod">DEGRADATION MODULE</a></li>
 
-
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/ConMod">CONVERTION MODULE</a></li>
 
-
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/RepMod">REPORTER MODULE</a></li>
 
-
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/SelfMod">SELF REGULATORY MODULE</a></li>
 
-
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/FutureSystem">FUTURE SYSTEM</a></li>
 
-
    </ul>
 
-
</li>
 
-
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/Modeling">MODELING</a></li>
 
-
<li>WETLAB
 
-
<ul>
 
-
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/protocol">PROTOCOL</a></li>
 
-
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/Parts">PARTS</a></li>
 
-
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/Attributions">ATTRIBUTIONS</a></li>
 
-
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/Safety">SAFETY</a></li>
 
-
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/Data">DATA</a></li>
 
-
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/ProteinModel">PROTEIN MODEL</a></li>
 
-
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/Achievement">ACHIEVEMENT</a></li>
 
-
</ul>
 
-
</li>
 
-
<li>NOTEBOOK
 
-
<ul>
 
-
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/nb-wetlab">WETLAB</a></li>
 
-
</ul>
 
-
</li>
 
-
<li>HUMAN PRACTICE
 
-
<ul>
 
-
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/Unpas">INTRO SYNBIO TO UNPAS</a></li>
 
-
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/SynBio">SYNBIO CLASS</a></li>
 
-
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/SynbiGreen">SYNBIGREEN SURVEY</a></li>
 
-
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/Medsos">SOCIAL MEDIA</a></li>
 
-
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/OnMedia">MEDIA</a></li>
 
-
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/Biosafety">BIOSAFETY SEMINAR</a></li>
 
-
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/MeetUp">INDONESIA TEAMS MEET UP</a></li>
 
-
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/Kids">FUN WITH KIDS</a></li>
 
-
<li><a href="https://2014.igem.org/Team:ITB_Indonesia/UPI">SHARING SYNBIO IN UPI</a></li>
 
-
</ul>
 
-
</li>
 
-
</ul>
 
-
</div>
 
-
 
-
<br>
 
-
<h1>CHAPERONE PROTEIN</h1>
 
-
<p>Amisfolded protein may form from aggregation of primary structure of protein that is overexpressed in the cell. This aggregation may create inclusion body which will lower the bacteria metabolic efficiency. If this condition is continuously happened, the death of the cell may occur. Therefore, it is important to decrease the inclusion body in the cell to increase the lifespan of the cell.</p>
 
-
<p>If chaperone is introduced to the system, it will act as an agent to refold the misfolded protein. This chaperone will be integrated in bacteria genome. The inclusion body then will be refolded and restore the activity of the protein as it normally would. With this system, the efficiency and effectiveness of bacteria recombinant gene expression and metabolic load will be better.</p>
 
-
 
-
<br>
 
-
<br>
 
-
 
-
<div id="sponsor"></div>
 
-
</div>
 
-
</div>
 
-
</body>
 
-
</html>
 
<html>
<html>
<head>
<head>

Latest revision as of 00:42, 18 October 2014


CHAPERONE PROTEIN

A misfolded protein may form from aggregation of primary structure of protein that is overexpressed in the cell. This aggregation may create inclusion body which will lower the bacteria metabolic efficiency. If this condition is continuously happened, the death of the cell may occur. Therefore, it is important to decrease the inclusion body in the cell to increase the lifespan of the cell.

If chaperone is introduced to the system, it will act as an agent to refold the misfolded protein. This chaperone will be integrated in bacteria genome. The inclusion body then will be refolded and restore the activity of the protein as it normally would. With this system, the efficiency and effectiveness of bacteria recombinant gene expression and metabolic load will be better.