Team:UC Santa Barbara

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<a href="https://2014.igem.org/Team:UC_Santa_Barbara/Parts"style="color:#000000"> Parts</a></td>
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<h3>Pathogen detection using an engineered contact-dependent inhibition system</h3></td></tr>
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<h3> Requirements </h3></td></tr>
 
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<p> Please be sure to keep these links, your audience will want to find your: </p>
 
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<li><a href="https://2014.igem.org/Team:UC_Santa_Barbara">Home</a> </li>
 
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<li><a href="https://2014.igem.org/Team:UC_Santa_Barbara/Team">Team</a> </li>
 
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<li><a href="https://igem.org/Team.cgi?year=2013&team_name=UC_Santa_Barbara">Official Team Profile</a> </li>
 
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<li><a href="https://2014.igem.org/Team:UC_Santa_Barbara/Project">Project</a> </li>
 
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<li><a href="https://2014.igem.org/Team:UC_Santa_Barbara/Parts">Parts</a> </li>
 
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<li><a href="https://2014.igem.org/Team:UC_Santa_Barbara/Modeling">Modeling</a> </li>
 
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<li><a href="https://2014.igem.org/Team:UC_Santa_Barbara/Notebook">Notebook</a> </li>
 
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<li><a href="https://2014.igem.org/Team:UC_Santa_Barbara/Safety">Safety</a> </li>
 
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<li>All pages, images and files must be hosted on the <a href ="https://2014.igem.org/Special:Upload">  2014.igem.org server</a>. </li>
 
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<li>All pages must be created under the team’s name space.</li>
 
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<li>As part of your documentation, keep the links from the menu to the left. </li>
 
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<li>The <a href="https://static.igem.org/mediawiki/igem.org/6/60/Igemlogo_300px.png"> iGEM logo </a> should be placed on the upper part of every page and should link to <a href="https://2014.igem.org/Main_Page">2014.igem.org</a>.</li>
 
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<p>Visit the <a href="https://2014.igem.org/Wiki_How-To"> Wiki How To page </a> for a complete list of requirements, tips and other useful information. </p>
 
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<p>We are currently working on providing teams with some easy to use design templates.
 
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<br> In the meantime you can also view other team wikis for inspiration! Here are some very good examples</p>
 
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<li> <a href="https://2013.igem.org/Team:SDU-Denmark/"> 2013 SDU Denmark </a> </li>
 
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<li> <a href="https://2013.igem.org/Team:SYSU-China">2013 SYSU China</a> </li>
 
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<li> <a href="https://2013.igem.org/Team:Shenzhen_BGIC_ATCG"> 2013 Shenxhen BGIG ATCG </a></li>
 
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<li> <a href="https://2013.igem.org/Team:Colombia_Uniandes">2013 Colombia Unianades </a></li>
 
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<li> <a href="https://2013.igem.org/Team:Lethbridge">2013 Lethbridge</a></li>
 
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<p>For a full wiki list, you can visit <a href="https://igem.org/Team_Wikis?year=2013">iGEM 2013 web sites </a> and <a href="https://igem.org/Team_Wikis?year=2012">iGEM 2012 web sites</a>  lists. </p>
 
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<p>This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started: </p>
 
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<li>State your accomplishments! Tell people what you have achieved from the start. </li>
 
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<li>Be clear about what you are doing and what you plan to do.</li>
 
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<li>You have a global audience! Consider the different backgrounds that your users come from.</li>
 
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<li>Make sure information is easy to find; nothing should be more than 3 clicks away.  </li>
 
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<li>Avoid using very small fonts and low contrast colors; information should be easy to read.  </li>
 
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<li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="">iGEM 2013 calendar</a> </li>
 
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<li>Have lots of fun! </li>
 
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Latest revision as of 01:53, 18 October 2014


Retrieved from "http://2014.igem.org/Team:UC_Santa_Barbara"
Home Team Official Team Profile Project Parts Human Practices Modeling Notebook Safety Attributions

Pathogen detection using an engineered contact-dependent inhibition system

The war on microbial pathogens is a complex issue, and will continue to be in the foreseeable future. Antibiotics target microbes once they have invaded their host, but this practice cannot continue forever due to bacteria’s ability to become resistant to the drugs administered. Here, we describe a novel use of recombinant biotechnology to generate Escherichia coli capable of both sensing and reporting the presence of pathogenic bacteria, by taking advantage of a pre-existing contact-dependent inhibition system. Coupling this contact-dependent system to gene control allows us to create a reporter bacterium that will glow on contact with pathogenic bacteria, exposing potential pathogens before they have a chance to infect their host. Dealing with post-infection situations will always be a necessity, but early detection and prevention will certainly lighten the load on an already strained scientific and medical community.​