Team:Tsinghua-A

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             <h2> To TALE a new world.  <a href="https://2014.igem.org/Team:Tsinghua-A/Project"><i class="icon-chevron-right"></i> See Project</a></h2>
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             <h1>Welcome to Tsinghua-A Team Wiki</h1>
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             <h2> Coding to reveal the code.   <a href="https://2014.igem.org/Team:Tsinghua-A/Modeling"><i class="icon-chevron-right"></i> See Modeling</a> </h2>
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             <h1>Welcome to Tsinghua-A Team Wiki</h1>
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             <h2> Practice humanity with technology. <a href="https://2014.igem.org/Team:Tsinghua-A/HumanPractice"><i class="icon-chevron-right"></i> See Human Practice</a> </h2>
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        <h2> Introduction </h2>
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           <h3>Transactivator-Like Effectors (TALEs) are a technology that once revolutionized the way researchers manipulate DNA with exceptional site specificity.Though it works well in eukaryotic organisms, it is not available in prokaryotic organisms. We come up with the idea that the long repeating sequence of the TALEs coding sequence leads to it. In our project, we attempt to construct a marvelous TALEs system which can efficiently work in prokaryotic organisms. By optimizing the TALEs coding sequence with modeling methods and testing it by Golden Gate Assembly and Report System, we hope we can have a handle tool for gene editing in prokaryotic organisms.
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            <h2>Project</h2>
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            <p>Background, hypothesis and workflow of designer TALE. </p>
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            <p>Optimization of TALE sequence and simulation of the gene circuit. </p>
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            <p>Lectures, seminar, questionnaires and raising ethic problems.  </p>
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            <h2>Team</h2>
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            <p>Department of Automatics, Life Science and Medical School. </p>
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          <h2> Acknowledgements </h2>
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                    <img src="https://static.igem.org/mediawiki/2014/4/45/Tsinghua-A_acc.png" alt="Title">
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Latest revision as of 03:01, 18 October 2014

Title

Introduction

Transactivator-Like Effectors (TALEs) are a technology that once revolutionized the way researchers manipulate DNA with exceptional site specificity.Though it works well in eukaryotic organisms, it is not available in prokaryotic organisms. We come up with the idea that the long repeating sequence of the TALEs coding sequence leads to it. In our project, we attempt to construct a marvelous TALEs system which can efficiently work in prokaryotic organisms. By optimizing the TALEs coding sequence with modeling methods and testing it by Golden Gate Assembly and Report System, we hope we can have a handle tool for gene editing in prokaryotic organisms.

Project

Background, hypothesis and workflow of designer TALE.

Modeling

Optimization of TALE sequence and simulation of the gene circuit.

Human Practice

Lectures, seminar, questionnaires and raising ethic problems.

Team

Department of Automatics, Life Science and Medical School.

Team

Title

Acknowledgements

Title

Retrieved from "http://2014.igem.org/Team:Tsinghua-A"