Team:TCU Taiwan/FutureWorks

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     <td width="68%" align="left" valign="middle"><h6><font face="Trebuchet MS" size="7" color="#484644">Modeling</font></h6></td>
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     <td width="68%" align="left" valign="middle"><h6><font face="Trebuchet MS" size="7" color="#484644">Future Works</font></h6></td>
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<li><a href="#" style="cursor:default"><font size="5">Team</font></a>
<li><a href="#" style="cursor:default"><font size="5">Team</font></a>
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       <li><a href="https://2014.igem.org/Team:TCU_Taiwan/Team"><font size="3">Team Members</font></a></li>
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       <li><a href="https://2014.igem.org/Team:TCU_Taiwan/Team"><font size="3">Members</font></a></li>
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      <li><a href="https://2014.igem.org/Team:TCU_Taiwan/Achievements"><font size="3">Achievements</font></a></li>
       <li><a href="https://igem.org/Team.cgi?id=1473" target="_blank"><font size="3">Official Team Profile</font></a></li>
       <li><a href="https://igem.org/Team.cgi?id=1473" target="_blank"><font size="3">Official Team Profile</font></a></li>
       <li><a href="https://2014.igem.org/Team:TCU_Taiwan/Contact"><font size="3">Contact</font></a></li>
       <li><a href="https://2014.igem.org/Team:TCU_Taiwan/Contact"><font size="3">Contact</font></a></li>
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       <li><a href="https://2014.igem.org/Team:TCU_Taiwan/Project"><font size="3">Project</font></a></li>
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       <li><a href="https://2014.igem.org/Team:TCU_Taiwan/Project"><font size="3">Introduction</font></a></li>
       <li><a href="https://2014.igem.org/Team:TCU_Taiwan/Parts"><font size="3">Parts</font></a></li>
       <li><a href="https://2014.igem.org/Team:TCU_Taiwan/Parts"><font size="3">Parts</font></a></li>
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      <li><a href="https://2014.igem.org/Team:TCU_Taiwan/SystemDesign"><font size="3">System Design</font></a></li>
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      <li><a href="https://2014.igem.org/Team:TCU_Taiwan/M13Phage"><font size="3">M13 Phage</font></a></li>
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      <li><a href="https://2014.igem.org/Team:TCU_Taiwan/CRISPR"><font size="3">CRISPR</font></a></li>
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      <li><a href="https://2014.igem.org/Team:TCU_Taiwan/FutureWorks"  style="color:#DBAC52"><font size="3">Future Works</font></a></li>
       <li><a href="https://2014.igem.org/Team:TCU_Taiwan/HumanPratics"><font size="3">Human Pratics</font></a></li>
       <li><a href="https://2014.igem.org/Team:TCU_Taiwan/HumanPratics"><font size="3">Human Pratics</font></a></li>
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   <li><a href="https://2014.igem.org/Team:TCU_Taiwan/Modeling"><font size="5">Modeling</font></a>
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     <td><font size="3" face="Verdana" color="#333"><p>In the future, we plan to make our Trogene  Horse become a substitute to antibiotics. Because antibiotic uses are forbidden  in some industry (ex. animal husbandry), there is no sense silencing resistance  gene in these parts.</p>
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  <legend class="qnum" align="center"><font face="Trebuchet MS" size="6" color="#0092C7">1.Introduction</font><br>
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     <td><font size="3" face="Verdana" color="#333"><p>We believe 16S rRNA gene can be the new target of our Trogene Horse. The 16S rRNA gene is a housekeeping gene, it has some special characters we are interested: </p>
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        1. Its presence in almost all microbe, and its sequence remains high conservation.<br />
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  <legend class="qnum" align="center"><font face="Trebuchet MS" size="6" color="#0092C7">2.Software</font><br>
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        2. The function of the 16S rRNA gene over time has not  changed (help constructing ribosome).</p>
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<div class="wrapper" style="background-color: white;"><p><font face="Trebuchet MS" size="5" color="#90B849">MATLAB</font><br><br>
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  <p class="qbody" align="justify"><font size="3" face="Verdana" color="#333"><img src="https://static.igem.org/mediawiki/2012/3/3f/MathWorks_logo.png" width="400" height="78" style=" float: right; margin-right: 5px; margin-left: 5px;">MATLAB(<strong>MAT</strong>rix <strong>LAB</strong>oratory) is a high-level language and interactive environment for numerical computation, visualization, and programming. Using MATLAB, you can analyze data, develop algorithms, and create models and applications. The language, tools, and built-in math functions enable you to explore multiple approaches and reach a solution faster than with spreadsheets or traditional programming languages, such as C/C++ or Java™.</font></p>
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<font size="3" face="Verdana" color="#333">The architecture and learning procedure underlying ANFIS (<strong>A</strong>daptive <strong>N</strong>etwork-based <strong>F</strong>uzzy <strong>I</strong>nference <strong>S</strong>ystem) is presented, which is a fuzzy inference system implemented in the framework of adaptive networks. By using a hybrid learning procedure, the proposed ANFIS can construct an input-output mapping based on both human knowledge (in the form of fuzzy if-then rules) and stipulated input-output data pairs. In the simulation, the ANFIS architecture is employed to model nonlinear functions, identify nonlinear components on-line in a control system, and predict a chaotic time series, all yielding remarkable results. Comparisons with artificial neural networks and earlier work on fuzzy modeling are listed and discussed.</font></div>
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    <td><font size="3" face="Verdana" color="#333"><p>Because  16S rRNA is necessary for ribosome and it exists  among microbes, knock-out of its gene will  block gene expression and inhibit growth of target bacteria. This  shall avoid co-effect of antibiotic use and remains high efficiency because we  use phages as vector.</p>
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    <td><font size="3" face="Verdana" color="#333"><p>Reference: <em>JOURNAL  OF CLINICAL MICROBIOLOGY</em> , Vol. 45, No. 9</p></font></td>
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<p>If you choose to create a model during your project, please write about it here. Modeling is not an essential part of iGEM, but we encourage any and all teams to model some aspect of their project. See previous "Best Model" awards for more information.</p>
 
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Latest revision as of 17:31, 17 October 2014


 
Future Works
  
 

In the future, we plan to make our Trogene Horse become a substitute to antibiotics. Because antibiotic uses are forbidden in some industry (ex. animal husbandry), there is no sense silencing resistance gene in these parts.
 
 

We believe 16S rRNA gene can be the new target of our Trogene Horse. The 16S rRNA gene is a housekeeping gene, it has some special characters we are interested:


1. Its presence in almost all microbe, and its sequence remains high conservation.
2. The function of the 16S rRNA gene over time has not changed (help constructing ribosome).
 
 

Because 16S rRNA is necessary for ribosome and it exists among microbes, knock-out of its gene will block gene expression and inhibit growth of target bacteria. This shall avoid co-effect of antibiotic use and remains high efficiency because we use phages as vector.
 

Reference: JOURNAL OF CLINICAL MICROBIOLOGY , Vol. 45, No. 9
 
^


    
Team Members Project Parts Human Pratics Modeling Safety Notebook Attributions

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