Team:Braunschweig

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         <title>E. Cowli - Fighting Climate Change - iGEM 2014 Team Braunschweig</title>
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         <title>E.&nbsp;cowli - Fighting Climate Change - iGEM 2014 Team Braunschweig</title>
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                  <li><a target="_blank" href="https://igem.org/Team.cgi?year=2014&team_name=Braunschweig">Official Team Profile</a></li>  
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                     <li><a target="_blank" href="https://2014.igem.org/Team:Braunschweig/Project">Summary</a></li>
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                     <li><a href="https://2014.igem.org/Team:Braunschweig/HP#spreading">Spreading the Word</a></li>
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             <li id="navbarnotebook"><a href="https://2014.igem.org/Team:Braunschweig/Notebook">Notebook</a>
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                                 <h1><i>E. Cowli</i></h1>
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                                 <h1><i style="font-size:50px">E.&nbsp;cowli</i></h1>
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                                 <p style="font-size:34px">Fighting Climate Change at the Source</p>
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                                 <p style="font-size:47px">Fighting Climate Change at the Source</p>
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                                     <h1>Slider 1 links</h1>
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                                     <h1><i style="font-size:38px">Kofi Annan</i></h1>
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                                        <p>Suspendisse pellentesque, odio vel ultricies interdum, mauris nulla ullamcorper magna, non aliquet odio velit aliquam augue.</p>
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<p style="font-size:30px">"On climate change, we often don't fully appreciate that it is a problem. We think it is a problem waiting to happen."</p>
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                                     <h1><i style="font-size:38px">Bill Gates</i></h1>
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                                        <p>Class aptent taciti sociosqu ad litora torquent per conubia nostra, per inceptos himenaeos. Nullam mattis fringilla urna.</p>
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                                    <p style="font-size:30px">"Climate change is a terrible problem, and it absolutely needs to be solved. It deserves to be a huge priority."</p>  
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                                 <h1>Slider 2</h1>
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                                 <h1><i style="font-size:45px">Bill Nye</i></h1>
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                                    <p>This template is free to download and use for any website. This is a mobile-ready layout using Bootstrap framework.</p>
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<p style="font-size:43px">"Climate change is happening, humans are causing it, and I think this is perhaps the most serious environmental issue facing us."</p>
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<h1><i>E. Cowli</i> - Fighting climate change at the source </h1>
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<h1><i>E.&nbsp;cowli</i> - Fighting climate change at the source </h1>
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<p class="mr">Dairy and beef production are important to our daily lives and consumption needs. However, there are serious climate change issues regarding the continual expansion of these industries. The microbiota inside the cow’s rumen releases dangerous amounts of greenhouse gases as they help digest the animal's food. Therefore, finding ways to decrease the production of greenhouse gases of dairy cows and cattle is essential in fighting global warming.
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<p class="mr" style="text-align:justify;">Dairy and beef production are important to our daily lives and consumption needs. However, there are serious climate change issues regarding the continual expansion of these industries. The natural microbiota inside the cow’s rumen releases dangerous amounts of greenhouse gases as they help digest the animal's food. Therefore, finding ways to decrease the production of greenhouse gases of dairy cows and cattle is essential in fighting global warming. </p>
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<h3 align="center">In this year’s iGEM project, we fight global warming right at the source - the cow's rumen.</h3><br>
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In this year’s iGEM project we fight global warming right at its source - the cow's rumen. Using the powerful tools of synthetic biology we were able to reduce the methane levels through a genetically engineered <i>E. coli</i>. </p>
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<p class="mr" style="text-align:justify;">Using the powerful tools of synthetic biology we make it possible to reduce the methane levels through a genetically engineered bacterium named <i>E.&nbsp;cowli</i>, using the soluble form of the enzyme complex methane monooxygenase (sMMO) for hydroxylation of methane to methanol. We successfully expressed all the subunits in soluble form and, furthermore, were able to prove the activity of the whole enzyme complex. Moreover, the effectivity, feasibility as well as the safety of this project was evaluated using a mathematical model. <br><br>
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Besides the laboratory-related topics, we also initialized many more activities to spread the idea of synthetic biology and iGEM. On various occasions we had the chance to present ourselves and our project to the broad public. We taught synthetic biology not only in a lecture but also 1-on-1 in a hands-on internship with a pupil and we also used these events for evaluation of the people's opinions on synthetic biology and consumption of animal products. In many discussions with other teams we took the chance to debate iGEM-related topics such as ethics, safety and intellectual property.<br>
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Get started and find out more about us and our project!</p>
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     The TU-DAY is the open day of our university, the Technische Universität (TU) Braunschweig. The event is aimed at a wide audience and not restricted to people engaged in science.
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     We are this year's iGEM Team of the Technische Universität Braunschweig. Get to know us, our motivations and much more on our team profiles!
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The European Researchers’ Night is an annual event “dedicated to popular science and fun learning”, as the organizers put it - and we were eager to live up to that!
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iGEM is more than only working in a lab - it's spreading the word. Find out more about our events and actions on our Policy and Practices page.
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     <span class="box_header">Modeling</span><br/>
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The “Tag der Lehre” (translates to “Day of Teaching”) hosted by our university is dedicated to the appreciation of innovative teaching concepts ...
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   <p class="box_text">In August we had a visitor in our lab for two weeks. Benjamin, a pupil from a local school, had decided to expand his knowledge on Synthetic Biology and Biotechnology. He proved to be very keen to learn new things and to become a valuable albeit short-term member of our team. Here is how he evaluates his stay with us.
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<h1>Project</h1></a>
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   <p class="box_text">The iGEM Team Braunschweig presents a novel approach towards the reduction of greenhouse gas emissions: We are going to equip the model organism <i>Escherichia coli</i> with the soluble methane monooxygenase (sMMO), an enzyme complex enabling methanotrophs to use the greenhouse gas methane as sole source of carbon and energy, hence creating our methane degrading <i>E.&nbsp;cowli</i>.
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    <a href="https://2014.igem.org/Team:Braunschweig/Safety">
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    <span class="box_header">Safety</span><br/>
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While designing our project, safety naturally was a very important issue for this year’s iGEM project. Issues in biosafety as well as gas health and safety were addressed.
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    <span class="box_header">Notebook</span><br/>
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Everyone who is interested in how we spent our iGEM summer, feel free to have a look at our Notebook, where we put together a documentation of our lab work.
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    <span class="box_header">Achievements</span><br/>
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By contributing BioBricks to the iGEM Registry of Standard Biological Parts so that other teams can use them in the future, we live up to the basic ideas of the iGEM competition.
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                         <div class="footer_bottom_content">Copyright © 2014 iGEM Team Braunschweig<br>
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Latest revision as of 20:24, 17 October 2014

E. cowli - Fighting Climate Change - iGEM 2014 Team Braunschweig

E. cowli - Fighting climate change at the source

Dairy and beef production are important to our daily lives and consumption needs. However, there are serious climate change issues regarding the continual expansion of these industries. The natural microbiota inside the cow’s rumen releases dangerous amounts of greenhouse gases as they help digest the animal's food. Therefore, finding ways to decrease the production of greenhouse gases of dairy cows and cattle is essential in fighting global warming.

In this year’s iGEM project, we fight global warming right at the source - the cow's rumen.


Using the powerful tools of synthetic biology we make it possible to reduce the methane levels through a genetically engineered bacterium named E. cowli, using the soluble form of the enzyme complex methane monooxygenase (sMMO) for hydroxylation of methane to methanol. We successfully expressed all the subunits in soluble form and, furthermore, were able to prove the activity of the whole enzyme complex. Moreover, the effectivity, feasibility as well as the safety of this project was evaluated using a mathematical model.

Besides the laboratory-related topics, we also initialized many more activities to spread the idea of synthetic biology and iGEM. On various occasions we had the chance to present ourselves and our project to the broad public. We taught synthetic biology not only in a lecture but also 1-on-1 in a hands-on internship with a pupil and we also used these events for evaluation of the people's opinions on synthetic biology and consumption of animal products. In many discussions with other teams we took the chance to debate iGEM-related topics such as ethics, safety and intellectual property.
Get started and find out more about us and our project!

Team

We are this year's iGEM Team of the Technische Universität Braunschweig. Get to know us, our motivations and much more on our team profiles!

Policy & Practices

iGEM is more than only working in a lab - it's spreading the word. Find out more about our events and actions on our Policy and Practices page.

Modeling

To evaluate the feasibilty of our project before has become reality we generated generated a mathematical model based on laboratory and literature data.

Kuh

Project

The iGEM Team Braunschweig presents a novel approach towards the reduction of greenhouse gas emissions: We are going to equip the model organism Escherichia coli with the soluble methane monooxygenase (sMMO), an enzyme complex enabling methanotrophs to use the greenhouse gas methane as sole source of carbon and energy, hence creating our methane degrading E. cowli.

Safety

While designing our project, safety naturally was a very important issue for this year’s iGEM project. Issues in biosafety as well as gas health and safety were addressed.

Notebook

Everyone who is interested in how we spent our iGEM summer, feel free to have a look at our Notebook, where we put together a documentation of our lab work.

Achievements

By contributing BioBricks to the iGEM Registry of Standard Biological Parts so that other teams can use them in the future, we live up to the basic ideas of the iGEM competition.

Our Supporters

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