Team:Oxford/team

Dr George Wadhams

George Wadhams’ research interests lie in how bacteria sense and integrate environmental information. His group focuses on understanding in a quantitative manner how multiple, homologous pathways operate in individual cells and how the components of these pathways can be used to create synthetic pathways.

Dr Ciarán Kelly

Ciarán Kelly obtained a PhD for his work in Frank Sargant’s group, constructing and characterising synthetic biohydrogen production pathways in E. coli. He is interested in the construction, characterisation, and re-engineering synthetic enzymes and pathways for the production of high-value chemicals.

Mr Karl Brune

Karl Brune's research interests lie in elucidating metabolic pathways. His previous work at Imperial College London was focused on engineering microbial consortia to enhance biomining and bioremediation, as well as on the study of photoautotrophic organisms.

Professor Judy Armitage

Judy Armitage is interested in the dynamics of bacterial sensory transduction and the control of bacterial motility. In particular, her research group focuses on the communication between the sensory and adaption mechanisms of the two pathways as a model for sensory network integration in general..

Professor Anthony Watts

Anthony Watts’ group is devising solid state NMR methods for determining high-resolution details of information-rich sites within membrane receptors. Recent focus has been on the neurotensin receptor (NTS1), which is now available highly purified and monodispersed in detergent as well as in a ligand-binding form.

Professor Antonis Papachristodoulou

Antonis Papachristodoulou’s research interests include systems and synthetic biology, network systems, aerospace systems and flow control, and convex optimisation. Furthermore, he works on modern control theory, robust stability analysis and design, as well as nonlinear dynamical systems and Lyapunov stability.

Andreas Harris

Andreas Harris works on the design and implementation of gene regulatory networks harnessing feedback to increase robustness and tunability. The designs are based around transcriptional networks and attempt to translate well-understood control modules, such as proportional and integral controllers, to biological systems.

Dr Lucas Black

Lucas is an imaging specialist helping out with quantification of parts and to give general guidance throughout the project. The team is very grateful for Lucas's excellent photography, including our team photos and the photograph of the Radcliffe Camera on our homepage.

All molecular biology, biochemical and fluorescence work was performed by student team members: Glen; Philipp; Francesca; Corinna; Andrew; and Emily in the lab of Prof. Judith Armitage under supervision of Dr. George Wadhams, Dr. Ciaran Kelly, Karl Brune and Dr. Lucas Black.

Interlab measurement study was performed by Tim under supervision of Lucas. All modelling was performed by student team members: Oliver; Matthew; and Leroy under the supervision of Dr. Antonis Papachristodolou and Andreas Harris.

Human Practices was performed by Sian and Francesca.

Biobead synthesis was performed Jack under supervision of Dr. George Wadhams.

Wiki design and coding was done by Jack and Oliver, with debug help from Ashok Menon and Josef Patoprsty.

With thanks:
Darragh Ennis
For his 3D printing expertise.

Dr Frederic Coulon (Department of Environmental Science and Technology, School of Applied Sciences, Cranfield University)
For his information on DCM and water treatment.

Shaun Rowson (Team Leader - Groundwater & Contaminated Land, Environment Agency)
For his detailed information on the problem of chlorinated solvents and how they are currently disposed of.

Janet Stott and Sarah Lloyd
For their kind advice and assistance in our public engagement events at the Oxford University Museum of Natural History.

Carla Brown
For generously donating several packs of her Bacteria Combat card game.

Paul Howard and Cameron Marshall of Carpmaels and Ransford
For their support with the Policy and Practices aspect of the project and for sharing their Intellectual Property wisdom.

Michael MorrisonHeLEX (Centre for Law, Health, and Emerging Technlogies)

For his support and advice with the Policy and Practices element of our work.