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| | <ul class="menu"> | | <ul class="menu"> |
| | <li class="menu"> <a class="menu" href="https://2014.igem.org/Team:Cooper_Union"> Home </a> </li> | | <li class="menu"> <a class="menu" href="https://2014.igem.org/Team:Cooper_Union"> Home </a> </li> |
| - | <li class="menu"> Project | + | <li class="menu-project"> Project |
| | <ul class="menu"> | | <ul class="menu"> |
| | <li class="menu"> <a class="menu" href="https://2014.igem.org/Team:Cooper_Union/TdT_project">De Novo Synthesis </a></li> | | <li class="menu"> <a class="menu" href="https://2014.igem.org/Team:Cooper_Union/TdT_project">De Novo Synthesis </a></li> |
| - | <li class="menu"> <a class="menu" href="https://2014.igem.org/Team:Cooper_Union/Telomere_project">Programmable Lifespan</a> </li> | + | <li class="menu"> <a class="menu" href="https://2014.igem.org/Team:Cooper_Union/Telomere_project">Programmable Lifespan Timer</a> </li> |
| | <li class="menu"> <a class="menu" href="https://2014.igem.org/Team:Cooper_Union/Biohack_project">Biohacker Kit </a></li> | | <li class="menu"> <a class="menu" href="https://2014.igem.org/Team:Cooper_Union/Biohack_project">Biohacker Kit </a></li> |
| | <li class="menu"> <a class="menu" href="https://2014.igem.org/Team:Cooper_Union/Hardware">OpenSource Hardware </a> </li> | | <li class="menu"> <a class="menu" href="https://2014.igem.org/Team:Cooper_Union/Hardware">OpenSource Hardware </a> </li> |
| | + | <!--<li class="menu"> <a class="menu" href="https://2014.igem.org/Team:Cooper_Union/Modeling">Modeling </a> </li>--> |
| | <li class="menu"> <a class="menu" href="https://2014.igem.org/Team:Cooper_Union/Parts">BioBrick Parts </a></li> | | <li class="menu"> <a class="menu" href="https://2014.igem.org/Team:Cooper_Union/Parts">BioBrick Parts </a></li> |
| - | <li class="menu"> <a class="menu" href="https://2014.igem.org/Team:Cooper_Union/Modeling">Modeling </a> </li>
| |
| | </ul> | | </ul> |
| | </li> | | </li> |
| - | <li class="menu"> <a class="menu" href="https://igem.org/Safety/Safety_Form?team_id=1354">Safety</a> </li> | + | <li class="menu-safety"> Security |
| - | <li class="menu"><a class="menu" href="https://2014.igem.org/Team:Cooper_Union/Outreach"> Outreach </a></li> | + | <ul class="menu"> |
| - | <li class="menu"> Notebook | + | <li class="menu"><a class="menu" href="https:// 2014.igem.org /Team:Cooper_Union/Safety ">Safety</ a> </li> |
| | + | <li class="menu"><a class="menu" href="https://2014.igem.org/Team:Cooper_Union/Ethics">Ethics</a> </li> |
| | + | </ul> |
| | + | </li> |
| | + | <li class="menu -outreach"><a class="menu" href="https://2014.igem.org/Team:Cooper_Union/Outreach">Outreach </a></li> |
| | + | <li class="menu-notebook"> Notebook |
| | <ul class="menu"> | | <ul class="menu"> |
| | <li class="menu"> <a class="menu" href="https://2014.igem.org/Team:Cooper_Union/Protocols">Commonly Used Protocols </li> | | <li class="menu"> <a class="menu" href="https://2014.igem.org/Team:Cooper_Union/Protocols">Commonly Used Protocols </li> |
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| | </ul> | | </ul> |
| | </li> | | </li> |
| - | <li class="menu"> Team | + | <li class="menu-team"> Team |
| | <ul class="menu"> | | <ul class="menu"> |
| | <li class="menu"> <a class="menu" href="https://2014.igem.org/Team:Cooper_Union/biofanfic">Members </a> </li> | | <li class="menu"> <a class="menu" href="https://2014.igem.org/Team:Cooper_Union/biofanfic">Members </a> </li> |
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| | </div> | | </div> |
| - | | + | <br> |
| | + | <hr> |
| | + | <br> |
| | + | <div class="text"> |
| | <!-----Add content below----> | | <!-----Add content below----> |
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| | </div> | | </div> |
| | | | |
| - | <div class="text"> | + | <div class="center"> |
| - | <h1>Micro-Toolbox: Open Source Solutions for DNA Synthesis, Biosafety and SynBio Education. | + | <h1>Open Source Solutions for DNA Synthesis, Biosafety and SynBio Education. |
| | | | |
| | </h1> | | </h1> |
| - | | + | </div> |
| | | | |
| | <hr /> | | <hr /> |
| - | | + | <div class="text"> |
| | <br> | | <br> |
| | Tools that compress the “design-build-test” cycle in synthetic biology are especially needed to reliably advance scientific proof-of-concepts to the industrial scale. As DNA synthesis continues to be a major bottleneck for R&D, our open source solution utilizes a novel enzymatic approach towards controllable <em>de novo</em> DNA synthesis, which is performed rapidly, inexpensively and less toxic than current methods. With speedy synthesis comes greater responsibility in industry towards biosafety; we propose the ultimate kill switch mechanism - a yeast-based chassis that features a programmable lifespan based on telomeres. Simplified DNA assembly will lead to a greater emphasis on pathway design and characterization in bioengineering programs. For schools, our "Biohacker Kit" utilizes a modular input/output binary plasmid platform that allows students to rapidly generate and test multiple biosensor configurations, with no “cutting and pasting” required. Additionally, inexpensive access to quality laboratory gear will be made possible by our “Open Hardware” collection of devices. | | Tools that compress the “design-build-test” cycle in synthetic biology are especially needed to reliably advance scientific proof-of-concepts to the industrial scale. As DNA synthesis continues to be a major bottleneck for R&D, our open source solution utilizes a novel enzymatic approach towards controllable <em>de novo</em> DNA synthesis, which is performed rapidly, inexpensively and less toxic than current methods. With speedy synthesis comes greater responsibility in industry towards biosafety; we propose the ultimate kill switch mechanism - a yeast-based chassis that features a programmable lifespan based on telomeres. Simplified DNA assembly will lead to a greater emphasis on pathway design and characterization in bioengineering programs. For schools, our "Biohacker Kit" utilizes a modular input/output binary plasmid platform that allows students to rapidly generate and test multiple biosensor configurations, with no “cutting and pasting” required. Additionally, inexpensive access to quality laboratory gear will be made possible by our “Open Hardware” collection of devices. |
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| | <br><br> | | <br><br> |
| | <p> | | <p> |
| - | <a href="http://www.cooper.edu" target="_blank" title="The Cooper Union for the Advancement of Science and Art"><img src="https://static.igem.org/mediawiki/2014/f/fe/Cooper-Union.png" title="The Cooper Union Advancement for the Advancement of Science and Art" height="200px" /></a><br> | + | <a href="http://www.cooper.edu" target="_blank" title="The Cooper Union for the Advancement of Science and Art"><img src="https://static.igem.org/mediawiki/2014/f/fe/Cooper-Union.png" title="The Cooper Union Advancement for the Advancement of Science and Art" height="150px" /></a><br> |
| | Through outstanding academic programs in architecture, art and engineering, and a Faculty of Humanities and Social Sciences, The Cooper Union for the Advancement of Science and Art prepares talented students to make enlightened contributions to society. | | Through outstanding academic programs in architecture, art and engineering, and a Faculty of Humanities and Social Sciences, The Cooper Union for the Advancement of Science and Art prepares talented students to make enlightened contributions to society. |
| | </p> | | </p> |
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| | <div class="sponsors" align="center"> | | <div class="sponsors" align="center"> |
| | | | |
| - | <em>Special Thanks to:</em> <br> | + | <em>Special Thanks to:</em> <br><br> |
| - | <a href="http://www.cooper.edu/about/trustees/jeremy-wertheimer" target="_blank">Jeremy Wertheimer</a>, for his generous contribution<br>that made all this possible.<br> | + | <a href="http://www.cooper.edu/about/trustees/jeremy-wertheimer" target="_blank">Jeremy Wertheimer</a>,<br>for his generous contribution<br>that made all this possible.<br><br> |
| - | <a href="http://www.hms.harvard.edu/agingresearch/index.php" target="_blank" title="David Sinclair, PhD and The Paul F. Glenn Laboratories for the Biological Mechanisms of Aging"><img src="https://static.igem.org/mediawiki/2014/3/33/CU_glennfound.png" /><img src="https://static.igem.org/mediawiki/2014/b/bc/CU_Harvardmed.jpg" /></a><br /> | + | <a href="http://www.hms.harvard.edu/agingresearch/index.php" target="_blank" title="David Sinclair, PhD and The Paul F. Glenn Laboratories for the Biological Mechanisms of Aging"><img src="https://static.igem.org/mediawiki/2014/3/33/CU_glennfound.png" /><img src="https://static.igem.org/mediawiki/2014/b/bc/CU_Harvardmed.jpg" /></a><br><br> |
| | <a href="http://www.genspace.org" target="_blank" title="Genspace - for providing us with equipment when we needed it"><img src="http://genspace.org/static/img/Genspace_logo.png?5B4RHexi" /></a> | | <a href="http://www.genspace.org" target="_blank" title="Genspace - for providing us with equipment when we needed it"><img src="http://genspace.org/static/img/Genspace_logo.png?5B4RHexi" /></a> |
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