Team:Tufts

From 2014.igem.org

(Difference between revisions)
 
(87 intermediate revisions not shown)
Line 1: Line 1:
-
{{CSS/Main}}
+
{{:Team:Tufts/Templates/Header}}
-
<html>
+
-
<!--<script>
+
-
  (function(i,s,o,g,r,a,m){i['GoogleAnalyticsObject']=r;i[r]=i[r]||function(){
+
-
  (i[r].q=i[r].q||[]).push(arguments)},i[r].l=1*new Date();a=s.createElement(o),
+
-
  m=s.getElementsByTagName(o)[0];a.async=1;a.src=g;m.parentNode.insertBefore(a,m)
+
-
  })(window,document,'script','//www.google-analytics.com/analytics.js','ga');
+
-
 
+
-
  ga('create', 'UA-43576754-1', 'igem.org');
+
-
  ga('send', 'pageview');
+
-
 
+
-
</script> -->
+
-
<!--
+
-
  <style type="text/css">
+
-
    * {
+
-
        font-size: 97%;
+
-
      }
+
-
    #contentSub, #search-controls, .firstHeading, #footer-box, #catlinks, #p-logo {
+
-
      display:none;
+
-
      }
+
-
    #top-section {
+
-
      border: none;
+
-
      height: 0px;
+
-
    }
+
-
 
+
-
    #menubar{
+
-
      display: none;
+
-
    }
+
-
 
+
-
    #menubar :hover{
+
-
      visibility: visible;
+
-
    }
+
-
    #content {
+
-
      background: none;
+
-
      border: none;
+
-
      width: 100%}
+
-
    #bodyContent{
+
-
     
+
-
      width:100%;
+
-
    }
+
-
#headingmain{
+
-
    font-size: 52px;
+
-
    position: absolute;
+
-
    margin-left: 183px;
+
-
    margin-right: auto;
+
-
    margin-top: 26px;
+
-
}
+
-
  </style>
+
-
  -->
+
-
  <html>
+
-
   
+
-
    <link href="//netdna.bootstrapcdn.com/bootstrap/3.0.0/css/bootstrap.min.css" rel="stylesheet">
+
-
    <script src="//ajax.googleapis.com/ajax/libs/jquery/1.10.2/jquery.min.js"></script>
+
-
    <script src="//netdna.bootstrapcdn.com/bootstrap/3.0.0/js/bootstrap.min.js"></script>
+
-
    <script src="http://getbootstrap.com/assets/js/holder.js"></script>
+
-
    <link href="//netdna.bootstrapcdn.com/font-awesome/3.2.1/css/font-awesome.css" rel="stylesheet">
+
-
 
+
-
    <link href='http://fonts.googleapis.com/css?family=Sigmar+One' rel='stylesheet' type='text/css'>
+
-
    <link href='http://fonts.googleapis.com/css?family=Cantora+One' rel='stylesheet' type='text/css'>
+
-
    <link href='http://fonts.googleapis.com/css?family=Rammetto+One' rel='stylesheet' type='text/css'>
+
-
   
+
-
    <!-- For Overriding Defualt Wiki banners and links-->
+
-
  <style type="text/css">
+
-
      #contentSub, #search-controls, .firstHeading, #footer-box, #catlinks, #p-logo {
+
-
        display:none;
+
-
      }
+
-
      #top-section {
+
-
        border: none;
+
-
        height: 0px;
+
-
      }
+
-
      .iitmofflogo {
+
-
        float:left;
+
-
      }
+
-
/*
+
-
      #menubar{
+
-
        display: none;
+
-
      }
+
-
*/
+
-
      .sub-heading1{
+
-
        text-align: center;
+
-
      }
+
-
      #menubar :hover{
+
-
        visibility: visible;
+
-
      }
+
-
      #content {
+
-
        background: none;
+
-
        border: none;
+
-
        width: 100%}
+
-
      #bodyContent{
+
-
       
+
-
        width:100%;
+
-
      }
+
-
      .navbar {
+
-
        height: 50px;
+
-
        width: 100%;
+
-
      }
+
-
      .navbar-right{
+
-
        padding-right: 30;
+
-
      }
+
-
      .navbar-brand{
+
-
        font-family: 'Sigmar One', cursive;
+
-
        font-size: 20;
+
-
      }
+
-
      .navbar{
+
-
        font-family: 'Cantora One', sans-serif;
+
-
      }
+
-
  </style>
+
-
 
+
-
  <script type="text/javascript">
+
-
    $(function(){
+
-
      var
+
-
          $win = $(window),
+
-
          $filter = $('.navbar'),
+
-
          $filterSpacer = $('<div />', {
+
-
            "class": "filter-drop-spacer",
+
-
            "height": $filter.outerHeight()
+
-
          }
+
-
                          );
+
-
      $win.scroll(function(){
+
-
       
+
-
        if(!$filter.hasClass('navbar-fixed-top')){
+
-
          if($win.scrollTop() > $filter.offset().top){
+
-
            $filter.before($filterSpacer);
+
-
            $filter.addClass("navbar-fixed-top");
+
-
          }
+
-
        }
+
-
        if ($filter.hasClass('navbar-fixed-top')){
+
-
          if($win.scrollTop() < $filterSpacer.offset().top){
+
-
            $filter.removeClass("navbar-fixed-top");
+
-
            $filterSpacer.remove();
+
-
          }
+
-
        }
+
-
       
+
-
      }
+
-
                );
+
-
    }
+
-
    );
+
-
   
+
-
  </script>
+
-
   
+
-
  <div class="header">
+
-
    <div class="container">
+
-
     
+
-
 
+
-
<img id="logo" src=" " style="max-height: 100px; max-width: 100;"/>
+
-
   
+
-
<div class="heading visible-tablet visible-desktop" style="
+
-
    font-size: 30px;
+
-
    position: absolute;
+
-
    margin-left: 350px;
+
-
    margin-right: auto;
+
-
    top: 45px;
+
-
    font-family: 'Rammetto One', cursive;">
+
-
  Tufts University</div>
+
-
   
+
-
    <div class="pull-right" style="text-align:right;">
+
-
      <table border="0">
+
-
        <tr>
+
-
          <td>
+
-
            <!--<a href="http://www.iitm.ac.in" target="_blank">
+
-
              <img id="iitmlogo" src="http://www.ee.iitm.ac.in/~ani/2013/ee5390/style/iitm_logo.gif" style="max-height: 100px; max-width: 60;"/>
+
-
            </a>-->
+
-
          </td>
+
-
          <td>
+
-
            <a href="https://2014.igem.org/Main_Page" target="_blank">
+
-
              <img id="igem-logo" src="http://upload.wikimedia.org/wikipedia/en/d/d6/IGEM_official_logo.png" style="width: 129px;">
+
-
            </a>
+
-
          </td>
+
-
        </tr>
+
-
      </table>
+
-
    </div>
+
-
  </div>
+
-
  </div>
+
-
 
+
-
  <div class="navbar navbar-inverse">
+
-
    <div class="navbar-header">
+
-
      <button type="button" class="navbar-toggle" data-toggle="collapse" data-target=".navbar-collapse">
+
-
        <span class="icon-bar">
+
-
          <i class="icon-home icon-large icon-white"></i>
+
-
        </span>
+
-
        <span class="icon-bar">
+
-
        </span>
+
-
        <span class="icon-bar">
+
-
        </span>
+
-
      </button>
+
-
      <a class="navbar-brand" href="#">
+
-
       
+
-
      </a>
+
-
    </div>
+
-
    <div class="navbar-collapse collapse">
+
-
      <ul class="nav navbar-nav">
+
-
       
+
-
        <li>
+
-
          <a href="https://2014.igem.org/Team:Tufts">
+
-
            <i class="icon-home icon-large icon-white"></i>
+
-
            Home
+
-
          </a>
+
-
        </li>
+
-
        <li class="dropdown">
+
-
          <a href="#" class="dropdown-toggle" data-toggle="dropdown">
+
-
            <i class="icon-gears icon-large"></i>
+
-
            Project
+
-
            <b class="caret">
+
-
            </b>
+
-
          </a>
+
-
          <ul class="dropdown-menu">
+
-
            <li>
+
-
              <a href="https://2014.igem.org/Team:Tufts/Ribosponge">
+
-
                Ribosponge
+
-
              </a>
+
-
            </li>
+
-
            <li>
+
-
              <a href="https://2014.igem.org/Team:Tufts/Synenergene">
+
-
                SYNENERGENE Collaboration
+
-
              </a>
+
-
            </li>
+
-
            <li>
+
-
              <a href="https://2014.igem.org/Team:Tufts/Medal">
+
-
                Medal Fulfillment
+
-
              </a>
+
-
            </li>
+
-
        <!--    <li class="divider">
+
-
            </li>
+
-
           
+
-
<li class="dropdown-header">
+
-
Nav header
+
-
</li>
+
-
-->
+
-
               
+
-
            </ul>
+
-
            </li>
+
-
            <li class="dropdown">
+
-
              <a href="#" class="dropdown-toggle" data-toggle="dropdown">
+
-
                <i class="icon-male icon-large"></i>
+
-
                Human Practices
+
-
                <b class="caret"></b>
+
-
              </a><ul class="dropdown-menu">
+
-
                <li>
+
-
                  <a href="https://2013.igem.org/Team:Tufts/PSB">
+
-
                    PSB Research
+
-
                  </a>
+
-
                </li>
+
-
                <li>
+
-
                  <a href="https://2013.igem.org/Team:Tufts/Qualtrics">
+
-
                  Tufts Qualtrics
+
-
                  </a>
+
-
                </li>
+
-
                <li>
+
-
                  <a href="https://2013.igem.org/Team:Tufts/Results">
+
-
                  Results
+
-
                  </a>
+
-
                </li>
+
-
              </ul>
+
-
            </li>
+
-
           
+
-
            <li class="dropdown">
+
-
              <a href="#" class="dropdown-toggle" data-toggle="dropdown">
+
-
                <i class="icon-group icon-large"></i>
+
-
                Team
+
-
                <b class="caret">
+
-
                </b>
+
-
              </a>
+
-
              <ul class="dropdown-menu">
+
-
                <li>
+
-
                  <a href="https://2014.igem.org/Team:Tufts/Bios">
+
-
                    Team Bios
+
-
                  </a>
+
-
                </li>
+
-
          <li class="divider">
+
-
            </li>
+
-
                <li>
+
-
                  <a target="_blank" href="https://igem.org/Team.cgi?year=2014&team_name=Tufts">
+
-
                    Official Team Profile
+
-
                  </a>
+
-
                </li>
+
-
              </ul>
+
-
            </li>
+
-
            <li class="dropdown">
+
-
              <a href="#" class="dropdown-toggle" data-toggle="dropdown">
+
-
                <i class="icon-book icon-large"></i>
+
-
                Notebook
+
-
                <b class="caret">
+
-
                </b>
+
-
              </a>
+
-
              <ul class="dropdown-menu">
+
-
               
+
-
                <li>
+
-
                  <a href="https://2013.igem.org/Team:IIT_Madras/Protocol">
+
-
                    Protocols
+
-
                  </a>
+
-
                </li>
+
-
                <li>
+
-
                  <a href="https://2013.igem.org/Team:IIT_Madras/Weekly">
+
-
                    Weekly Summaries
+
-
                  </a>
+
-
                </li>
+
-
              </ul>
+
-
            </li>
+
-
            <li>
+
-
              <a href="https://2013.igem.org/Team:IIT_Madras/Attributions">
+
-
                <i class="icon-flag icon-large"></i>
+
-
                Attributions
+
-
              </a>
+
-
            </li>
+
-
           
+
-
 
+
-
          </ul>
+
-
          <ul class="nav navbar-nav navbar-right">
+
-
            <li>
+
-
              <a target="_blank" href="http://www.facebook.com/iitmigem">
+
-
                <i class="icon-facebook icon-large icon-white"></i>
+
-
               
+
-
              </a>
+
-
            </li>
+
-
            <li>
+
-
              <!--<a href="http://twitter.com/junaid_babu">
+
-
              <i class="icon-twitter icon-large"></i>
+
-
              </a>-->
+
-
<div class="navbar-header">
+
-
     
+
-
    </div>
+
-
            </li>
+
-
          </ul>
+
-
  </div>
+
-
  <!--/.nav-collapse -->
+
-
  </div>
+
<html>
<html>
Line 335: Line 10:
         <li data-target="#myCarousel" data-slide-to="2" class=""></li>
         <li data-target="#myCarousel" data-slide-to="2" class=""></li>
         <li data-target="#myCarousel" data-slide-to="3" class=""></li>
         <li data-target="#myCarousel" data-slide-to="3" class=""></li>
 +
        <li data-target="#myCarousel" data-slide-to="4" class=""> </li>
 +
        <li data-target="#myCarousel" data-slide-to="5" class=""> </li>
 +
       </ol>
       </ol>
       <div class="carousel-inner">
       <div class="carousel-inner">
          
          
         <div class="item active">
         <div class="item active">
-
           <img src="https://static.igem.org/mediawiki/2013/d/db/Iitm13_Slide_1.jpg" alt="Second slide" style="height: 500px; width: 100%; display: block;">
+
           <center><img src=" https://static.igem.org/mediawiki/2014/c/c7/Tufts_phage.jpg" alt="Second slide" style="height: 475px; width: 68%; display: block;"></center>
           <div class="container">
           <div class="container">
             <div class="carousel-caption">
             <div class="carousel-caption">
-
              <!--<h1>The Team</h1>
 
-
              <p>Cras justo odio, dapibus ac facilisis in, egestas eget quam. Donec id elit non mi porta gravida at eget metus. Nullam id dolor id nibh ultricies vehicula ut id elit.</p>
 
-
              <p><a class="btn btn-large btn-primary" href="#">More info</a></p>-->
 
-
 
 
-
<marquee behavior="scroll" direction="left" style="
 
-
    color: black;
 
-
    font-weight: bold;
 
-
    font-size: 52px;
 
-
    height: 50px
 
-
;
 
-
    padding-top: 10px;
 
-
">COMBATING SHIGA TOXIN</marquee>
 
             </div>
             </div>
           </div>
           </div>
         </div>
         </div>
-
 
-
 
-
 
-
 
         <div class="item">
         <div class="item">
-
           <img src="https://static.igem.org/mediawiki/2013/f/f5/Iitm13_Slide_2.jpg" alt="Third slide" style="height: 500px; width: 100%; display: block;">
+
           <center><img src="https://static.igem.org/mediawiki/2014/0/09/Conf1.jpg" alt="Third slide" style="height: 475px; width: 68%; display: block;"></center>
           <div class="container">
           <div class="container">
             <div class="carousel-caption">
             <div class="carousel-caption">
Line 370: Line 32:
           </div>
           </div>
         </div>
         </div>
-
<div class="item">
+
      <div class="item">
-
           <img src="https://static.igem.org/mediawiki/2013/a/a7/Iitm13_Slide_3.jpg" alt="Third slide" style="height: 500px; width: 100%; display: block;">
+
           <center><img src="https://static.igem.org/mediawiki/2014/e/e7/140310_13187_venter127_%281%29.jpg" " alt="Third slide" style="height: 475px; width: 68%; display: block;"></center>
           <div class="container">
           <div class="container">
             <div class="carousel-caption">
             <div class="carousel-caption">
Line 378: Line 40:
           </div>
           </div>
         </div>
         </div>
-
<div class="item">
+
     
-
           <img src="https://static.igem.org/mediawiki/2013/4/4f/Iitm13_Slide_4.jpg" alt="Third slide" style="height: 500px; width: 100%; display: block;">
+
      <div class="item">
 +
           <center><img src="https://static.igem.org/mediawiki/2014/3/33/Lab7.jpg" alt="Third slide" style="height: 475px; width: 68%; display: block;"></center>
           <div class="container">
           <div class="container">
             <div class="carousel-caption">
             <div class="carousel-caption">
                
                
             </div>
             </div>
-
            
+
           </div>
-
 
+
         </div>
         </div>
 +
        <div class="item">
 +
          <center><img src=" https://static.igem.org/mediawiki/2014/c/c9/Lab5.jpg" alt="Third slide" style="height: 475px; width: 68%; display: block;"></center>
 +
          <div class="container">
 +
            <div class="carousel-caption">
 +
            </div>
 +
          </div>
         </div>
         </div>
-
<div class="item">
+
 
-
           <img src="https://static.igem.org/mediawiki/2013/b/b8/Last_slide_edit.jpg" alt="Third slide" style="height: 500px; width: 100%; display: block;">
+
      <div class="item">
 +
           <center><img src=" https://static.igem.org/mediawiki/2014/8/81/Lab9.jpg" alt="Third slide" style="height: 475px; width: 68%; display: block;"></center>
           <div class="container">
           <div class="container">
             <div class="carousel-caption">
             <div class="carousel-caption">
-
             
 
             </div>
             </div>
           </div>
           </div>
         </div>
         </div>
 +
 +
       </div>
       </div>
       <a class="left carousel-control" href="#myCarousel" data-slide="prev"><span class="glyphicon glyphicon-chevron-left"></span></a>
       <a class="left carousel-control" href="#myCarousel" data-slide="prev"><span class="glyphicon glyphicon-chevron-left"></span></a>
Line 404: Line 74:
       <div class="row featurette">
       <div class="row featurette">
-
         <div class="col-md-7">
+
         <div class="col-md-12" style="font-size:15px">
-
          Shiga toxin, a worldwide menace, has killed over 1 million people to date and continues to afflict almost 150 million people each year. Currently, there is no treatment for Shiga toxicosis and it leads to complications in the human system like hemolytic uremic syndrome (HUS) and renal failure. Here, we propose a two-fold, novel synthetic biology approach to combat the lethal effect of the toxin. We aim to neutralize the already produced toxin through a nine amino acid Gb3 mimic peptide. We have engineered the Gb3 mimic along with a cellular export signal (ompF) downstream of AHL(quorum sensing molecule) inducible promoter (pLuxR). We also plan to prevent further toxin production by inhibiting the biofilm formation of shigatoxigenic E.coli using indole-3-acetaldehyde (I3A). We expect to validate our approach through functional assays and in silico modelling. Our findings can potentially initiate a new perspective of tackling Shiga toxicosis using synthetic biology tools.
+
 
 +
        Tufts iGEM seeks to expand undergraduate science education and allow students to take part in all aspects of the research process, from drafting proposals, to securing funding, and finally carrying out the research in lab. These projects expose students not only to the technical aspects of synthetic biology but also to the social, legal, and ethical implications generated by their work. The team is composed of passionate individuals from all fields of study, who are driven to investigate and address pertinent issues in medicine, health, technology, research, and bioethics. In addition to carrying out undergraduate, self-directed research, the Tufts iGEM team teaches and mentors underclassmen, develops relationships with professors, and generally works to promote the involvement of undergraduates in biological research.  
       </div>
       </div>
<div class="col-md-3">
<div class="col-md-3">
-
<img src="https://static.igem.org/mediawiki/2013/6/61/Iitm13_team_pic.JPG" width="100%" style="
+
<img src="" width="100%" style="
     padding-top: 33px;
     padding-top: 33px;
     width: 458px;
     width: 458px;

Latest revision as of 01:34, 18 October 2014

Tufts University

Tufts iGEM seeks to expand undergraduate science education and allow students to take part in all aspects of the research process, from drafting proposals, to securing funding, and finally carrying out the research in lab. These projects expose students not only to the technical aspects of synthetic biology but also to the social, legal, and ethical implications generated by their work. The team is composed of passionate individuals from all fields of study, who are driven to investigate and address pertinent issues in medicine, health, technology, research, and bioethics. In addition to carrying out undergraduate, self-directed research, the Tufts iGEM team teaches and mentors underclassmen, develops relationships with professors, and generally works to promote the involvement of undergraduates in biological research.

Retrieved from "http://2014.igem.org/Team:Tufts"