Team:Berlin/Header

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     <meta name="description" content="In October 2014, a team of Berlin students from a variety of backgrounds are participating
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     <meta name="description" content="Remote-controlled E.coli bacteria? That’s the aim of the interdisciplinary iGEM Team Berlin!">
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for the first time in the in the international genetically engineered machines competition.
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For our project, the iGEM Berlin team has decided to make E. coli bacteria susceptible to
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magnetic fields. By knocking out the iron efflux transporter (FieF) and iron uptake
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suppressor (FUR), we want to increase the total iron level of the cytosol. By sequestering
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iron in a ferritin protein, iron crystals are formed and the cell is detoxified. In order
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to create ferromagnetic of super paramagnetic crystals, we will then use an intensive high
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through put media optimization to discover the best conditions for the formation of magnetic
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nanoparticles in E. coli. Furthermore, we will work with other metal binding proteins like
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metallothioneins and phytochelatin synthases in order to achieve nanoparticle synthesis in
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E. coli. Once we have discovered the best way to magnetize E. coli bacteria we will build
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and characterize a suitable BioBrick that can be used by any research lab or iGEM team in
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the world in order to remote control the movement of E. coli cells.">
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     <meta name="author" content="Marius Wessel and Valerian Blos">
     <meta name="author" content="Marius Wessel and Valerian Blos">
      
      
      
      
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Latest revision as of 10:03, 2 October 2014

iGEM Berlin 2014 | TU-Berlin