Team:Imperial

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                        <h1>Imperial College </h1>
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                         <h2>Customisable Ultrafiltration Membranes from Bacterial Cellulose</h2>
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                         <h2>iGEM 2014</h2>
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                         <h2>The Project</h2>
                         <h2>The Project</h2>
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                             <p>Cellulose is the most abundant organic polymer found in nature. Plants, bacteria and even some animals utilise it for applications such as support, adhesion, protection and flotation. We find cellulose in our everyday lives; from being the main constituent of cotton to uses in medicine and scientific research. </p>
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                             <p>Bacterial cellulose (BC) is a natural biomaterial that is of interest in many fields due to its high purity compared with plant-derived cellulose. We are optimising BC biosynthesis in <em>Gluconacetobacter xylinus</em>, transferring the system to <em>E. coli</em>, and functionalising the material using proteins in order to expand its properties. </p> <p>BC has seen use in clothing and health foods, but we develop its application to the global issue of water purification. Rising demand for limited freshwater supplies will lead to more than half of the global population suffering severe water stress by 2030. Improved filtration techniques would help relieve this problem.</p><p> The porosity of BC and our synthetic attachment of contaminant-specific binding and catabolic proteins make for a flexible, modular water filter. Our manufactured biomaterial would augment water recycling and reclamation on local and industrial scales, helping to alleviate water stress.</p>
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<p>Much of the cellulose we use is derived from plants as a mixture with other compounds and so requires an energy intensive purification step. Bacteria offer an alternative means of production that produces a cellulose that is purer and requires less processing.</p>
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<p>In our project we optimise the production of bacterial cellulose by engineering <em>Gluconacetobacter xylinus</em> and transferring the system into <em>E. coli</em>. We also functionalise our cellulose in order to expand its mechanical, chemical and biological properties into new areas of use.</p>
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                             <div class="more-box "><a href="https://2014.igem.org/Team:Imperial/Project">read more...</a>
                             <div class="more-box "><a href="https://2014.igem.org/Team:Imperial/Project">read more...</a>
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                                         <h2>The Team</h2>
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                                         <h2>Implementation</h2>
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                                         <h3>Meet Our Members</h3>
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                                         <h3>Our final idea</h3>
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                                         <div class="more-box"><a href="https://2014.igem.org/Team:Imperial/Students">read more</a>
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                                         <div class="more-box"><a href="https://2014.igem.org/Team:Imperial/Implementation">read more</a>
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                                         <h2>Lorem Ipsum</h2>
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                                         <a href="https://2014.igem.org/Team:Imperial/Results"><h2>Main Achievements</h2></a>
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                                         <h3>Blah blah blah</h3>
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                                        <div class="more-box"><a href="#">read more</a>
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                                            <li><a href="https://2014.igem.org/Team:Imperial/Functionalisation">Functionalised BC using CBD fusions</a></li>
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                                            <li><a href="https://2014.igem.org/Team:Imperial/Gluconacetobacter">Created a library of <em>G. xylinus</em> parts</a></li>
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                                            <li><a href="https://2014.igem.org/Team:Imperial/Parts">Created over 100 constructs</a></li>
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                                            <li><a href="https://2014.igem.org/Team:Imperial/Gluconacetobacter#genome_sequencing">Sequenced two genomes</a></li>
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                                            <li><a href="https://2014.igem.org/Team:Imperial/EColi">Achieved cellulose production in <em>E.coli</em></a></li>
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                                        <h2>Water Report</h2>
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                                        <h3>The Liquid of Life</h3>
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                                        <div class="more-box"><a href="https://2014.igem.org/Team:Imperial/Water_Report">read more</a>
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Latest revision as of 03:55, 18 October 2014

Imperial iGEM 2014

Aqualose

The Project

Bacterial cellulose (BC) is a natural biomaterial that is of interest in many fields due to its high purity compared with plant-derived cellulose. We are optimising BC biosynthesis in Gluconacetobacter xylinus, transferring the system to E. coli, and functionalising the material using proteins in order to expand its properties.

BC has seen use in clothing and health foods, but we develop its application to the global issue of water purification. Rising demand for limited freshwater supplies will lead to more than half of the global population suffering severe water stress by 2030. Improved filtration techniques would help relieve this problem.

The porosity of BC and our synthetic attachment of contaminant-specific binding and catabolic proteins make for a flexible, modular water filter. Our manufactured biomaterial would augment water recycling and reclamation on local and industrial scales, helping to alleviate water stress.

read more...

Implementation

Our final idea

read more

Main Achievements

Water Report

The Liquid of Life

read more

Latest Tweet

All tweets @imperialigem

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