Team:Virtus-Parva Mexico

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{{Team:VirtusParva/MainCss}}
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<body>
<body>
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<source src="https://static.igem.org/mediawiki/2014/e/e6/Team_Virtus_Parva_Logo_Video.mov"></video></td>
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                    <a href="https://2014.igem.org/Team:Virtus-Parva_Mexico" class="navbar-brand">Virtus Parva Home</a>
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                            <a href="#sec">Project</a>
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                        </li>
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                        <li>
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                            <a href="#sec">Outcomes</a>
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                        </li>
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                        <li>
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                            <a href="#sec">Our Team</a>
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                        </li>
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                        <li>
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                            <a href="#sec1">Safety</a>
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                        </li>
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                        <li>
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                            <a href="#sec">Human Practices</a>
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<!-- Content goes here -->
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<h1><font color=#FFFFFF size=7> Bio-NEMS Drill!</font></h1>
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            <video autoplay>
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<h3><p align="left">Traditionally pathogens have been annihilated using pharmaceuticals, but today nanotechnology offers a new possibility with the use of nanoelectromechanical systems (NEMS). We present a novel device that could make these processes possible: <em>the BioNEMS Drill</em>. This is a magnetic portion of chromatin. To construct the device we synthesized hydrophilic magnetite. We used it due to its bio-compatibility for medical applications and later functionalized them with amino groups, which can establish a peptide bond between nanoparticles and a protein. We used the HU histone-like protein, capable of coiling DNA around the nanoparticles. To get enough protein, we modified E. Coli to overexpress it. Since the core of the device is magnetic it can be controlled by applying an external magnetic field. Furthermore, the versatility of the DNA to be coated with various materials and its functionalization can selectively remove certain chemicals inside the human body such as cholesterol or toxic agents.</h3></p>
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        if ("undefined" == typeof jQuery) throw new Error("Bootstrap's JavaScript requires jQuery"); +function (a) { "use strict"; function b() { var a = document.createElement("bootstrap"), b = { WebkitTransition: "webkitTransitionEnd", MozTransition: "transitionend", OTransition: "oTransitionEnd otransitionend", transition: "transitionend" }; for (var c in b) if (void 0 !== a.style[c]) return { end: b[c] }; return !1 } a.fn.emulateTransitionEnd = function (b) { var c = !1, d = this; a(this).one(a.support.transition.end, function () { c = !0 }); var e = function () { c || a(d).trigger(a.support.transition.end) }; return setTimeout(e, b), this }, a(function () { a.support.transition = b() }) }(jQuery), +function (a) { "use strict"; var b = '[data-dismiss="alert"]', c = function (c) { a(c).on("click", b, this.close) }; c.prototype.close = function (b) { function c() { f.trigger("closed.bs.alert").remove() } var d = a(this), e = d.attr("data-target"); e || (e = d.attr("href"), e = e && e.replace(/.*(?=#[^\s]*$)/, "")); var f = a(e); b && b.preventDefault(), f.length || (f = d.hasClass("alert") ? d : d.parent()), f.trigger(b = a.Event("close.bs.alert")), b.isDefaultPrevented() || (f.removeClass("in"), a.support.transition && f.hasClass("fade") ? f.one(a.support.transition.end, c).emulateTransitionEnd(150) : c()) }; var d = a.fn.alert; a.fn.alert = function (b) { return this.each(function () { var d = a(this), e = d.data("bs.alert"); e || d.data("bs.alert", e = new c(this)), "string" == typeof b && e[b].call(d) }) }, a.fn.alert.Constructor = c, a.fn.alert.noConflict = function () { return a.fn.alert = d, this }, a(document).on("click.bs.alert.data-api", b, c.prototype.close) }(jQuery), +function (a) { "use strict"; var b = function (c, d) { this.$element = a(c), this.options = a.extend({}, b.DEFAULTS, d), this.isLoading = !1 }; b.DEFAULTS = { loadingText: "loading..." }, b.prototype.setState = function (b) { var c = "disabled", d = this.$element, e = d.is("input") ? "val" : "html", f = d.data(); b += "Text", f.resetText || d.data("resetText", d[e]()), d[e](f[b] || this.options[b]), setTimeout(a.proxy(function () { "loadingText" == b ? (this.isLoading = !0, d.addClass(c).attr(c, c)) : this.isLoading && (this.isLoading = !1, d.removeClass(c).removeAttr(c)) }, this), 0) }, b.prototype.toggle = function () { var a = !0, b = this.$element.closest('[data-toggle="buttons"]'); if (b.length) { var c = this.$element.find("input"); "radio" == c.prop("type") && (c.prop("checked") && this.$element.hasClass("active") ? a = !1 : b.find(".active").removeClass("active")), a && c.prop("checked", !this.$element.hasClass("active")).trigger("change") } a && this.$element.toggleClass("active") }; var c = a.fn.button; a.fn.button = function (c) { return this.each(function () { var d = a(this), e = d.data("bs.button"), f = "object" == typeof c && c; e || d.data("bs.button", e = new b(this, f)), "toggle" == c ? e.toggle() : c && e.setState(c) }) }, a.fn.button.Constructor = b, a.fn.button.noConflict = function () { return a.fn.button = c, this }, a(document).on("click.bs.button.data-api", "[data-toggle^=button]", function (b) { var c = a(b.target); c.hasClass("btn") || (c = c.closest(".btn")), c.button("toggle"), b.preventDefault() }) }(jQuery), +function (a) { "use strict"; var b = function (b, c) { this.$element = a(b), this.$indicators = this.$element.find(".carousel-indicators"), this.options = c, this.paused = this.sliding = this.interval = this.$active = this.$items = null, "hover" == this.options.pause && this.$element.on("mouseenter", a.proxy(this.pause, this)).on("mouseleave", a.proxy(this.cycle, this)) }; b.DEFAULTS = { interval: 5e3, pause: "hover", wrap: !0 }, b.prototype.cycle = function (b) { return b || (this.paused = !1), this.interval && clearInterval(this.interval), this.options.interval && !this.paused && (this.interval = setInterval(a.proxy(this.next, this), this.options.interval)), this }, b.prototype.getActiveIndex = function () { return this.$active = this.$element.find(".item.active"), this.$items = this.$active.parent().children(), this.$items.index(this.$active) }, b.prototype.to = function (b) { var c = this, d = this.getActiveIndex(); return b > this.$items.length - 1 || 0 > b ? void 0 : this.sliding ? this.$element.one("slid.bs.carousel", function () { c.to(b) }) : d == b ? this.pause().cycle() : this.slide(b > d ? "next" : "prev", a(this.$items[b])) }, b.prototype.pause = function (b) { return b || (this.paused = !0), this.$element.find(".next, .prev").length && a.support.transition && (this.$element.trigger(a.support.transition.end), this.cycle(!0)), this.interval = clearInterval(this.interval), this }, b.prototype.next = function () { return this.sliding ? void 0 : this.slide("next") }, b.prototype.prev = function () { return this.sliding ? void 0 : this.slide("prev") }, b.prototype.slide = function (b, c) { var d = this.$element.find(".item.active"), e = c || d[b](), f = this.interval, g = "next" == b ? "left" : "right", h = "next" == b ? "first" : "last", i = this; if (!e.length) { if (!this.options.wrap) return; e = this.$element.find(".item")[h]() } if (e.hasClass("active")) return this.sliding = !1; var j = a.Event("slide.bs.carousel", { relatedTarget: e[0], direction: g }); return this.$element.trigger(j), j.isDefaultPrevented() ? void 0 : (this.sliding = !0, f && this.pause(), this.$indicators.length && (this.$indicators.find(".active").removeClass("active"), this.$element.one("slid.bs.carousel", function () { var b = a(i.$indicators.children()[i.getActiveIndex()]); b && b.addClass("active") })), a.support.transition && this.$element.hasClass("slide") ? (e.addClass(b), e[0].offsetWidth, d.addClass(g), e.addClass(g), d.one(a.support.transition.end, function () { e.removeClass([b, g].join(" ")).addClass("active"), d.removeClass(["active", g].join(" ")), i.sliding = !1, setTimeout(function () { i.$element.trigger("slid.bs.carousel") }, 0) }).emulateTransitionEnd(1e3 * d.css("transition-duration").slice(0, -1))) : (d.removeClass("active"), e.addClass("active"), this.sliding = !1, this.$element.trigger("slid.bs.carousel")), f && this.cycle(), this) }; var c = a.fn.carousel; a.fn.carousel = function (c) { return this.each(function () { var d = a(this), e = d.data("bs.carousel"), f = a.extend({}, b.DEFAULTS, d.data(), "object" == typeof c && c), g = "string" == typeof c ? c : f.slide; e || d.data("bs.carousel", e = new b(this, f)), "number" == typeof c ? e.to(c) : g ? e[g]() : f.interval && e.pause().cycle() }) }, a.fn.carousel.Constructor = b, a.fn.carousel.noConflict = function () { return a.fn.carousel = c, this }, a(document).on("click.bs.carousel.data-api", "[data-slide], [data-slide-to]", function (b) { var c, d = a(this), e = a(d.attr("data-target") || (c = d.attr("href")) && c.replace(/.*(?=#[^\s]+$)/, "")), f = a.extend({}, e.data(), d.data()), g = d.attr("data-slide-to"); g && (f.interval = !1), e.carousel(f), (g = d.attr("data-slide-to")) && e.data("bs.carousel").to(g), b.preventDefault() }), a(window).on("load", function () { a('[data-ride="carousel"]').each(function () { var b = a(this); b.carousel(b.data()) }) }) }(jQuery), +function (a) { "use strict"; var b = function (c, d) { this.$element = a(c), this.options = a.extend({}, b.DEFAULTS, d), this.transitioning = null, this.options.parent && (this.$parent = a(this.options.parent)), this.options.toggle && this.toggle() }; b.DEFAULTS = { toggle: !0 }, b.prototype.dimension = function () { var a = this.$element.hasClass("width"); return a ? "width" : "height" }, b.prototype.show = function () { if (!this.transitioning && !this.$element.hasClass("in")) { var b = a.Event("show.bs.collapse"); if (this.$element.trigger(b), !b.isDefaultPrevented()) { var c = this.$parent && this.$parent.find("> .panel > .in"); if (c && c.length) { var d = c.data("bs.collapse"); if (d && d.transitioning) return; c.collapse("hide"), d || c.data("bs.collapse", null) } var e = this.dimension(); this.$element.removeClass("collapse").addClass("collapsing")[e](0), this.transitioning = 1; var f = function () { this.$element.removeClass("collapsing").addClass("collapse in")[e]("auto"), this.transitioning = 0, this.$element.trigger("shown.bs.collapse") }; if (!a.support.transition) return f.call(this); var g = a.camelCase(["scroll", e].join("-")); this.$element.one(a.support.transition.end, a.proxy(f, this)).emulateTransitionEnd(350)[e](this.$element[0][g]) } } }, b.prototype.hide = function () { if (!this.transitioning && this.$element.hasClass("in")) { var b = a.Event("hide.bs.collapse"); if (this.$element.trigger(b), !b.isDefaultPrevented()) { var c = this.dimension(); this.$element[c](this.$element[c]())[0].offsetHeight, this.$element.addClass("collapsing").removeClass("collapse").removeClass("in"), this.transitioning = 1; var d = function () { this.transitioning = 0, this.$element.trigger("hidden.bs.collapse").removeClass("collapsing").addClass("collapse") }; return a.support.transition ? void this.$element[c](0).one(a.support.transition.end, a.proxy(d, this)).emulateTransitionEnd(350) : d.call(this) } } }, b.prototype.toggle = function () { this[this.$element.hasClass("in") ? "hide" : "show"]() }; var c = a.fn.collapse; a.fn.collapse = function (c) { return this.each(function () { var d = a(this), e = d.data("bs.collapse"), f = a.extend({}, b.DEFAULTS, d.data(), "object" == typeof c && c); !e && f.toggle && "show" == c && (c = !c), e || d.data("bs.collapse", e = new b(this, f)), "string" == typeof c && e[c]() }) }, a.fn.collapse.Constructor = b, a.fn.collapse.noConflict = function () { return a.fn.collapse = c, this }, a(document).on("click.bs.collapse.data-api", "[data-toggle=collapse]", function (b) { var c, d = a(this), e = d.attr("data-target") || b.preventDefault() || (c = d.attr("href")) && c.replace(/.*(?=#[^\s]+$)/, ""), f = a(e), g = f.data("bs.collapse"), h = g ? "toggle" : d.data(), i = d.attr("data-parent"), j = i && a(i); g && g.transitioning || (j && j.find('[data-toggle=collapse][data-parent="' + i + '"]').not(d).addClass("collapsed"), d[f.hasClass("in") ? "addClass" : "removeClass"]("collapsed")), f.collapse(h) }) }(jQuery), +function (a) { "use strict"; function b(b) { a(d).remove(), a(e).each(function () { var d = c(a(this)), e = { relatedTarget: this }; d.hasClass("open") && (d.trigger(b = a.Event("hide.bs.dropdown", e)), b.isDefaultPrevented() || d.removeClass("open").trigger("hidden.bs.dropdown", e)) }) } function c(b) { var c = b.attr("data-target"); c || (c = b.attr("href"), c = c && /#[A-Za-z]/.test(c) && c.replace(/.*(?=#[^\s]*$)/, "")); var d = c && a(c); return d && d.length ? d : b.parent() } var d = ".dropdown-backdrop", e = "[data-toggle=dropdown]", f = function (b) { a(b).on("click.bs.dropdown", this.toggle) }; f.prototype.toggle = function (d) { var e = a(this); if (!e.is(".disabled, :disabled")) { var f = c(e), g = f.hasClass("open"); if (b(), !g) { "ontouchstart" in document.documentElement && !f.closest(".navbar-nav").length && a('<div class="dropdown-backdrop"/>').insertAfter(a(this)).on("click", b); var h = { relatedTarget: this }; if (f.trigger(d = a.Event("show.bs.dropdown", h)), d.isDefaultPrevented()) return; f.toggleClass("open").trigger("shown.bs.dropdown", h), e.focus() } return !1 } }, f.prototype.keydown = function (b) { if (/(38|40|27)/.test(b.keyCode)) { var d = a(this); if (b.preventDefault(), b.stopPropagation(), !d.is(".disabled, :disabled")) { var f = c(d), g = f.hasClass("open"); if (!g || g && 27 == b.keyCode) return 27 == b.which && f.find(e).focus(), d.click(); var h = " li:not(.divider):visible a", i = f.find("[role=menu]" + h + ", [role=listbox]" + h); if (i.length) { var j = i.index(i.filter(":focus")); 38 == b.keyCode && j > 0 && j--, 40 == b.keyCode && j < i.length - 1 && j++, ~j || (j = 0), i.eq(j).focus() } } } }; var g = a.fn.dropdown; a.fn.dropdown = function (b) { return this.each(function () { var c = a(this), d = c.data("bs.dropdown"); d || c.data("bs.dropdown", d = new f(this)), "string" == typeof b && d[b].call(c) }) }, a.fn.dropdown.Constructor = f, a.fn.dropdown.noConflict = function () { return a.fn.dropdown = g, this }, a(document).on("click.bs.dropdown.data-api", b).on("click.bs.dropdown.data-api", ".dropdown form", function (a) { a.stopPropagation() }).on("click.bs.dropdown.data-api", e, f.prototype.toggle).on("keydown.bs.dropdown.data-api", e + ", [role=menu], [role=listbox]", f.prototype.keydown) }(jQuery), +function (a) { "use strict"; var b = function (b, c) { this.options = c, this.$element = a(b), this.$backdrop = this.isShown = null, this.options.remote && this.$element.find(".modal-content").load(this.options.remote, a.proxy(function () { this.$element.trigger("loaded.bs.modal") }, this)) }; b.DEFAULTS = { backdrop: !0, keyboard: !0, show: !0 }, b.prototype.toggle = function (a) { return this[this.isShown ? "hide" : "show"](a) }, b.prototype.show = function (b) { var c = this, d = a.Event("show.bs.modal", { relatedTarget: b }); this.$element.trigger(d), this.isShown || d.isDefaultPrevented() || (this.isShown = !0, this.escape(), this.$element.on("click.dismiss.bs.modal", '[data-dismiss="modal"]', a.proxy(this.hide, this)), this.backdrop(function () { var d = a.support.transition && c.$element.hasClass("fade"); c.$element.parent().length || c.$element.appendTo(document.body), c.$element.show().scrollTop(0), d && c.$element[0].offsetWidth, c.$element.addClass("in").attr("aria-hidden", !1), c.enforceFocus(); var e = a.Event("shown.bs.modal", { relatedTarget: b }); d ? c.$element.find(".modal-dialog").one(a.support.transition.end, function () { c.$element.focus().trigger(e) }).emulateTransitionEnd(300) : c.$element.focus().trigger(e) })) }, b.prototype.hide = function (b) { b && b.preventDefault(), b = a.Event("hide.bs.modal"), this.$element.trigger(b), this.isShown && !b.isDefaultPrevented() && (this.isShown = !1, this.escape(), a(document).off("focusin.bs.modal"), this.$element.removeClass("in").attr("aria-hidden", !0).off("click.dismiss.bs.modal"), a.support.transition && this.$element.hasClass("fade") ? this.$element.one(a.support.transition.end, a.proxy(this.hideModal, this)).emulateTransitionEnd(300) : this.hideModal()) }, b.prototype.enforceFocus = function () { a(document).off("focusin.bs.modal").on("focusin.bs.modal", a.proxy(function (a) { this.$element[0] === a.target || this.$element.has(a.target).length || this.$element.focus() }, this)) }, b.prototype.escape = function () { this.isShown && this.options.keyboard ? this.$element.on("keyup.dismiss.bs.modal", a.proxy(function (a) { 27 == a.which && this.hide() }, this)) : this.isShown || this.$element.off("keyup.dismiss.bs.modal") }, b.prototype.hideModal = function () { var a = this; this.$element.hide(), this.backdrop(function () { a.removeBackdrop(), a.$element.trigger("hidden.bs.modal") }) }, b.prototype.removeBackdrop = function () { this.$backdrop && this.$backdrop.remove(), this.$backdrop = null }, b.prototype.backdrop = function (b) { var c = this.$element.hasClass("fade") ? "fade" : ""; if (this.isShown && this.options.backdrop) { var d = a.support.transition && c; if (this.$backdrop = a('<div class="modal-backdrop ' + c + '" />').appendTo(document.body), this.$element.on("click.dismiss.bs.modal", a.proxy(function (a) { a.target === a.currentTarget && ("static" == this.options.backdrop ? this.$element[0].focus.call(this.$element[0]) : this.hide.call(this)) }, this)), d && this.$backdrop[0].offsetWidth, this.$backdrop.addClass("in"), !b) return; d ? this.$backdrop.one(a.support.transition.end, b).emulateTransitionEnd(150) : b() } else !this.isShown && this.$backdrop ? (this.$backdrop.removeClass("in"), a.support.transition && this.$element.hasClass("fade") ? this.$backdrop.one(a.support.transition.end, b).emulateTransitionEnd(150) : b()) : b && b() }; var c = a.fn.modal; a.fn.modal = function (c, d) { return this.each(function () { var e = a(this), f = e.data("bs.modal"), g = a.extend({}, b.DEFAULTS, e.data(), "object" == typeof c && c); f || e.data("bs.modal", f = new b(this, g)), "string" == typeof c ? f[c](d) : g.show && f.show(d) }) }, a.fn.modal.Constructor = b, a.fn.modal.noConflict = function () { return a.fn.modal = c, this }, a(document).on("click.bs.modal.data-api", '[data-toggle="modal"]', function (b) { var c = a(this), d = c.attr("href"), e = a(c.attr("data-target") || d && d.replace(/.*(?=#[^\s]+$)/, "")), f = e.data("bs.modal") ? "toggle" : a.extend({ remote: !/#/.test(d) && d }, e.data(), c.data()); c.is("a") && b.preventDefault(), e.modal(f, this).one("hide", function () { c.is(":visible") && c.focus() }) }), a(document).on("show.bs.modal", ".modal", function () { a(document.body).addClass("modal-open") }).on("hidden.bs.modal", ".modal", function () { a(document.body).removeClass("modal-open") }) }(jQuery), +function (a) { "use strict"; var b = function (a, b) { this.type = this.options = this.enabled = this.timeout = this.hoverState = this.$element = null, this.init("tooltip", a, b) }; b.DEFAULTS = { animation: !0, placement: "top", selector: !1, template: '<div class="tooltip"><div class="tooltip-arrow"></div><div class="tooltip-inner"></div></div>', trigger: "hover focus", title: "", delay: 0, html: !1, container: !1 }, b.prototype.init = function (b, c, d) { this.enabled = !0, this.type = b, this.$element = a(c), this.options = this.getOptions(d); for (var e = this.options.trigger.split(" "), f = e.length; f--;) { var g = e[f]; if ("click" == g) this.$element.on("click." + this.type, this.options.selector, a.proxy(this.toggle, this)); else if ("manual" != g) { var h = "hover" == g ? "mouseenter" : "focusin", i = "hover" == g ? "mouseleave" : "focusout"; this.$element.on(h + "." + this.type, this.options.selector, a.proxy(this.enter, this)), this.$element.on(i + "." + this.type, this.options.selector, a.proxy(this.leave, this)) } } this.options.selector ? this._options = a.extend({}, this.options, { trigger: "manual", selector: "" }) : this.fixTitle() }, b.prototype.getDefaults = function () { return b.DEFAULTS }, b.prototype.getOptions = function (b) { return b = a.extend({}, this.getDefaults(), this.$element.data(), b), b.delay && "number" == typeof b.delay && (b.delay = { show: b.delay, hide: b.delay }), b }, b.prototype.getDelegateOptions = function () { var b = {}, c = this.getDefaults(); return this._options && a.each(this._options, function (a, d) { c[a] != d && (b[a] = d) }), b }, b.prototype.enter = function (b) { var c = b instanceof this.constructor ? b : a(b.currentTarget)[this.type](this.getDelegateOptions()).data("bs." + this.type); return clearTimeout(c.timeout), c.hoverState = "in", c.options.delay && c.options.delay.show ? void (c.timeout = setTimeout(function () { "in" == c.hoverState && c.show() }, c.options.delay.show)) : c.show() }, b.prototype.leave = function (b) { var c = b instanceof this.constructor ? b : a(b.currentTarget)[this.type](this.getDelegateOptions()).data("bs." + this.type); return clearTimeout(c.timeout), c.hoverState = "out", c.options.delay && c.options.delay.hide ? void (c.timeout = setTimeout(function () { "out" == c.hoverState && c.hide() }, c.options.delay.hide)) : c.hide() }, b.prototype.show = function () { var b = a.Event("show.bs." + this.type); if (this.hasContent() && this.enabled) { if (this.$element.trigger(b), b.isDefaultPrevented()) return; var c = this, d = this.tip(); this.setContent(), this.options.animation && d.addClass("fade"); var e = "function" == typeof this.options.placement ? this.options.placement.call(this, d[0], this.$element[0]) : this.options.placement, f = /\s?auto?\s?/i, g = f.test(e); g && (e = e.replace(f, "") || "top"), d.detach().css({ top: 0, left: 0, display: "block" }).addClass(e), this.options.container ? d.appendTo(this.options.container) : d.insertAfter(this.$element); var h = this.getPosition(), i = d[0].offsetWidth, j = d[0].offsetHeight; if (g) { var k = this.$element.parent(), l = e, m = document.documentElement.scrollTop || document.body.scrollTop, n = "body" == this.options.container ? window.innerWidth : k.outerWidth(), o = "body" == this.options.container ? window.innerHeight : k.outerHeight(), p = "body" == this.options.container ? 0 : k.offset().left; e = "bottom" == e && h.top + h.height + j - m > o ? "top" : "top" == e && h.top - m - j < 0 ? "bottom" : "right" == e && h.right + i > n ? "left" : "left" == e && h.left - i < p ? "right" : e, d.removeClass(l).addClass(e) } var q = this.getCalculatedOffset(e, h, i, j); this.applyPlacement(q, e), this.hoverState = null; var r = function () { c.$element.trigger("shown.bs." + c.type) }; a.support.transition && this.$tip.hasClass("fade") ? d.one(a.support.transition.end, r).emulateTransitionEnd(150) : r() } }, b.prototype.applyPlacement = function (b, c) { var d, e = this.tip(), f = e[0].offsetWidth, g = e[0].offsetHeight, h = parseInt(e.css("margin-top"), 10), i = parseInt(e.css("margin-left"), 10); isNaN(h) && (h = 0), isNaN(i) && (i = 0), b.top = b.top + h, b.left = b.left + i, a.offset.setOffset(e[0], a.extend({ using: function (a) { e.css({ top: Math.round(a.top), left: Math.round(a.left) }) } }, b), 0), e.addClass("in"); var j = e[0].offsetWidth, k = e[0].offsetHeight; if ("top" == c && k != g && (d = !0, b.top = b.top + g - k), /bottom|top/.test(c)) { var l = 0; b.left < 0 && (l = -2 * b.left, b.left = 0, e.offset(b), j = e[0].offsetWidth, k = e[0].offsetHeight), this.replaceArrow(l - f + j, j, "left") } else this.replaceArrow(k - g, k, "top"); d && e.offset(b) }, b.prototype.replaceArrow = function (a, b, c) { this.arrow().css(c, a ? 50 * (1 - a / b) + "%" : "") }, b.prototype.setContent = function () { var a = this.tip(), b = this.getTitle(); a.find(".tooltip-inner")[this.options.html ? 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Latest revision as of 03:55, 18 October 2014

Virtus Parva

Bio-NEMS Drill!


Traditionally pathogens have been annihilated using pharmaceuticals, but today nanotechnology offers a new possibility with the use of nanoelectromechanical systems (NEMS). We present a novel device that could make these processes possible: the BioNEMS Drill. This is a magnetic portion of chromatin. To construct the device we synthesized hydrophilic magnetite. We used it due to its bio-compatibility for medical applications and later functionalized them with amino groups, which can establish a peptide bond between nanoparticles and a protein. We used the HU histone-like protein, capable of coiling DNA around the nanoparticles. To get enough protein, we modified E. Coli to overexpress it. Since the core of the device is magnetic it can be controlled by applying an external magnetic field. Furthermore, the versatility of the DNA to be coated with various materials and its functionalization can selectively remove certain chemicals inside the human body such as cholesterol or toxic agents.

Retrieved from "http://2014.igem.org/Team:Virtus-Parva_Mexico"