Team:Georgia State

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Latest revision as of 03:49, 18 October 2014

Mamba | Georgia State University

Our team from Georgia State University has been working to successfully insert and purify mambalgin, a protein component of the venom of Dendroaspis Polylepis, better known as the Black Mamba. The mambalgin peptide is a powerful analgesic that directly blocks pain transmission in the peripheral nervous system (Diochot et al, 2012) by targeting acid sensing ion channels within nociceptors beneath the epidermis. Furthermore, recombinant purification of mambalgin could assist in developing anti-venom without the attendant risk of harvesting venom directly from snakes.

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-                                <h4>Building an Expression Vector</h4>
+                               <a href="https://static.igem.org/mediawiki/2014/e/ef/Step1.gif" target="_blank"><h4>Expression Vector</h4>
-                                 <p><img src="https://static.igem.org/mediawiki/2014/e/ef/Step1.gif" width="320" height="240" /></p>
+                                 <p><img src="https://static.igem.org/mediawiki/2014/e/ef/Step1.gif" width="246" height="185" /></p></a>
                                  <p><a href="https://2014.igem.org/Team:Georgia_State/Project_Summary/">Read more...</a></p>
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-                                 <h4>Transforming Linearized Mambalgin into <i>P. pastoris</i></h4>
+                                 <h4>Transformation</h4>
-                                 <p><img src="https://static.igem.org/mediawiki/2014/7/7c/Step2.gif" width="320" height="240" /></p>
+                                 <a href="https://static.igem.org/mediawiki/2014/7/7c/Step2.gif" target="_blank"><p><img src="https://static.igem.org/mediawiki/2014/7/7c/Step2.gif" width="246" height="185" /></p></a>
                                  <p><a href="https://2014.igem.org/Team:Georgia_State/Project_Summary/">Read more...</a></p>
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                                  <h4>Mambalgin Synthesis</h4>
-                                 <p><img src="https://static.igem.org/mediawiki/2014/5/5d/Step3.gif" width="320" height="240" /></p>
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                                  <p><a href="https://2014.igem.org/Team:Georgia_State/Project_Summary/">Read more...</a></p>
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+                             <div class="service-content" style="width:320; height:240;">
-                                 <h4>The Applications</h4>
+                                 <h4>Applications</h4>
-                                 <p>Mambalgin binds to the Acid Sensing Ion Channel (ASIC) in order to block pain signals. Mambalgin is as effective as opiate pain killers but is non-addictive.</p>
+                                 <p><img src="https://static.igem.org/mediawiki/2014/d/d6/Medicallogo.jpg" width="320" height="240" /></p>
                                  <p><a href="https://2014.igem.org/Team:Georgia_State/Project_Summary/">Read more...</a></p>
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-                     	<h4 class="classic-title"><span>Mamba: An entry into iGEM 2014</span></h4>
+                     	<h4 class="classic-title"><span>Mamba: GSU IGEM 2014</span></h4>
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-								<p>Our team from Georgia State University has been working to successfully insert and purify mambalgin, a protein component of the venom of Dendroaspis Polylepis, better known as the Black Mamba. The mambalgin peptide is a powerful analgesic that directly blocks pain transmission in the peripheral nervous system (Diochot et al, 2012) by targeting acid sensing ion channels within nociceptors beneath the epidermis. Furthermore, recombinant purification of mambalgin could assist in developing anti-venom without the attendant risk of harvesting venom directly from snakes.</p>
+								<p style="color:black;">Our team from Georgia State University has been working to successfully insert and purify mambalgin, a protein component of the venom of Dendroaspis Polylepis, better known as the Black Mamba. The mambalgin peptide is a powerful analgesic that directly blocks pain transmission in the peripheral nervous system (Diochot et al, 2012) by targeting acid sensing ion channels within nociceptors beneath the epidermis. Furthermore, recombinant purification of mambalgin could assist in developing anti-venom without the attendant risk of harvesting venom directly from snakes.</p>
 								<p></p>
 								<p><a href="https://2014.igem.org/Team:Georgia_State/Project_Summary/" class="btn-system btn-medium border-btn"><i class="icon-docs"></i> Read More</a></p>
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                      	<h4 class="classic-title"><span>From the Lab</span></h4>
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+                         <iframe src="//player.vimeo.com/video/109298011" width="500" height="281" frameborder="0" webkitallowfullscreen mozallowfullscreen allowfullscreen></iframe>
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+                    	<!-- Start Clients Carousel -->
+                            <div class="our-clients">
+                                <!-- Classic Heading -->
+                                <h4 class="classic-title"><span>Partners & Sponsors</span></h4>
+                                <div class="clients-carousel custom-carousel touch-carousel" data-appeared-items="4">
+                                    <!-- Client 1 -->
+                                    <div class="client-item item">
+                                        <a href="http://www.idtdna.com/site" target="_blank"><img src="https://static.igem.org/mediawiki/2014/9/99/IDTLogo.png" alt="" width="731" height="199" /></a>
+                                    </div>
+                                    <!-- Client 2 -->
+                                    <div class="client-item item" style="margin:0 auto;">
+                                        <a href="https://www.neb.com/" target="_blank"><img src="https://static.igem.org/mediawiki/2014/4/4e/SheffieldLogo3.png" alt="" width="345" height="138" /></a>
+                                    </div>
+                                    <!-- Client 3 -->
+                                    <div class="client-item item" style="margin:0 auto;">
+                                        <a href="http://www.atlantaga.gov/index.aspx?page=16" target="_blank"><img src="https://static.igem.org/mediawiki/2014/5/57/RESURGENSLogo.png" alt="" width="110" height="112" /></a>
+                                    </div>
+                                    <!-- Client 4 -->
+                                    <div class="client-item item" style="float:right;">
+                                        <a href="http://www.snapgene.com/" target="_blank"><img src="https://static.igem.org/mediawiki/2014/e/ec/Snapgenelogo.png" alt="" width="100" height="100" /></a>
+                                    </div>
+                                </div>
+                            </div>
+                            <!--End Clients Carousel-->
+                    </div>