Team:Sheffield/collaboration

From 2014.igem.org

(Difference between revisions)
 
(80 intermediate revisions not shown)
Line 1: Line 1:
{{Team:Sheffield/NavigationBar}}
{{Team:Sheffield/NavigationBar}}
<html>
<html>
-
<head>
+
    <head>
 +
        <style>
 +
            .section {
 +
                width: 960px;
 +
                margin-left: auto;
 +
                margin-right: auto;
 +
            }
-
<title></title>
+
            .fancyBlocks {
-
<link rel="stylesheet" href="https://2014.igem.org/Team:Sheffield/Template:Style.css?action=raw&ctype=text/css" type="text/css" media="all" />
+
                width: 960px;
-
<script src="https://2014.igem.org/Team:Sheffield/Template:jquery-1.10.1.min.js?action=raw&ctype=text/javascript"></script>
+
                margin-left: auto;
-
<script src="https://2014.igem.org/Team:Sheffield/Template:modernizr.custom.js?action=raw&ctype=text/javascript"></script>
+
                margin-right: auto;
 +
                padding-left: 5px;
 +
                padding-right: 5px;
 +
                vertical-align: top;
 +
                padding-top: 10px;
 +
                padding-bottom: 10px;
 +
                background-color: #21B8C6;
 +
                border-radius: 10px;
 +
                margin-top: 20px;
 +
                margin-bottom: 20px;
 +
            }
 +
            .video {
 +
                text-align: center;
 +
            }
-
<style type="text/css">
+
            .subPageTitle {
 +
                color: black;
 +
            }
 +
        </style>
-
body{
+
    </head>
-
height: 100%;
+
-
}
+
-
iframe{
+
    <body>
-
margin-right: 10em;
+
<div class="headerImage"><img src="https://static.igem.org/mediawiki/2014/4/4d/DSC03092crop_Sheffield2014.jpg"></div>
-
float: right;
+
        <h1 class="subPageTitle">Collaboration</h1>
-
}
+
        <div class="gap5px"></div>
 +
        <div class="section">
 +
            <h2>Meetups</h2>
 +
            <p>During the course of the project we formed collaborative links with a number of different iGEM teams to further integrate Sheffield into the iGEM community and establish potential associations for future iGEM teams from Sheffield. We attended the <a href="https://2014.igem.org/Team:Oxford">Oxford</a> iGEM Meet Up on Thursday, 19th June 2014 to meet with other iGEM teams from the UK and Ireland. This was a great day with interesting talks from guest speakers giving us insight into the project. Over a poster session we established links with other iGEM teams with whom we later collaborated. As it was early on in the project timeline, it was useful to see where projects were heading and also the variety of issues being tackled using synthetic biology.</p>
-
</style>
+
            <p>We hosted our own meet up on Friday, 18th July 2014, a month after the previous meet up. We felt that this would be a great time for us to solidify and identify specific areas and ideas on which we could collaborate with other teams, as other teams had started their lab work by this point. We met with the teams from <a href="https://2014.igem.org/Team:Kent">Kent</a>, <a href="https://2014.igem.org/Team:NRP-UEA-Norwich">NRP-UEA-Norwich</a>, <a href="https://2014.igem.org/Team:Oxford">Oxford</a> and <a href="https://2014.igem.org/Team:York">York</a>. Firstly, we had presentations from two guest speakers from the University of Sheffield: Professor Phillip C. Wright  (Head of Chemical and Biological Engineering) who spoke about the development of synthetic biology from an engineering perspective, and Robert Meckin (Doctoral Researcher, Science and Technology Studies) who gave an insight into human practices surrounding synthetic biology. An networking activity involving human bingo allowed us to find out more about each other before a poster session and followed by a more relaxed evening on the town. We had a great time hosting the teams and hope they did too! Below is a video to show a summary of the events that took place: </p>
-
</head>
+
            <div class="video"><object width="420" height="315" data="https://www.youtube.com/v/ONiWpZch58s"></object></div>  
 +
        </div>
 +
        <div class="fancyBlocks">
 +
            <h2>Edinburgh</h2>
 +
            <p>During the course of the project we established contact and collaborative links with a number of different iGEM teams. For instance, with Team Edinburgh we were in touch regarding Human Practices. During skype meetings we discussed our HP project approaches and decided there how our inter-team collaboration would work. Team sheffield was interviewed by team edinburgh over a skype call regarding task management and role distribution within a team. On the other hand, we asked some questions about the different components of their HP work, so that we could incorporate them in the SocioBrick Registry of standard parts that we developed for iGEM. We considered the collaboration successful in that each team was able to get the necessary data from each other to carry on their individual work. We then had a chance to personally meet some members of team Edinburgh in the Young Synthetic Biology Conference in London which was a wonderful further learn about the work they had been invested in as a whole.</p>
 +
        </div>
 +
        <div class="fancyBlocks">
 +
            <div style="width:10em; float:left;"><img src="https://static.igem.org/mediawiki/2014/a/a4/Oxigemsidebarlogo.png" width="100px"></div>
 +
            <div style="float:left; padding-top:15px;"><h2>Oxford</h2></div>
 +
            <div style="margin-top:9em;">
 +
                <p>The Oxford iGEM Team were one of the first teams we established collaborative links with after the meet-up they held in Oxford. When we held our own meet-up in Sheffield, our teams agreed that there was an overlap in the aims of our project.</p>
 +
                <p>Team Oxford were one of the first teams we established collaborative links with. After the University of Sheffield Meet-up organised by us, our teams felt their was an overlap in the way our teams worked and what we were addressing and therefore decided that if needed there were certain identified that we could definitely collaborate in. For instance in the beginning of the project our team was having trouble obtaining successful transformations of a certain promoter that we require and so asked if Oxford could try transforming it and see if they encountered the same problem. Oxford were very helpful and happy to do it. However, while this was taking place, our team troubleshooted what the problem had been.</p>
 +
                <p>Further down the line, Oxford started developing a stochastic modelling system. With that, they asked if we would be interested in giving them some info regarding the promoters we were testing with our lipase and copy number which we did to allow them to further improve their model.</p>
 +
            </div>
 +
        </div>
-
<body>
+
        <div class="fancyBlocks">
-
    <br><br><br><br>
+
            <div style="width:10em; float:left;"><img src="https://static.igem.org/mediawiki/2014/2/28/Logorose.png" width="100px"></div>
-
    <iframe width="420" height="315" src="http://www.youtube.com/embed/XGSy3_Czz8k"></iframe>
+
            <div style="float:left; padding-top:15px;"><h2>Paris Bettencourt</h2></div>
-
    <br><br><br><br><br><br><br><br><br><br><br><br>
+
            <div style="margin-top:8em;">
 +
                <p>The Paris Bettencourt iGEM team was a team we collaborated with in their efforts to build a synthetic biology community for iGEM teams. We have participated in their fortnightly  newsletter with a sizeable number of other iGEM teams from around the world, updating the participating teams with our progress so far and answering the questions asked by other teams. The newsletter was particularly successful and helped the Sheffield team integrate into the iGEM community. </p>
 +
                <p>We also participated in the development of Paris Bettencourt’s MOOC (Massively Open Online Course), run on Genius online knowledge base website, on which we annotated some of the entries and hope to continue to edit in future.</p>
 +
            </div>
 +
        </div>
-
 
+
        <div class="fancyBlocks">
-
    <ul id="og-grid" class="og-grid">
+
            <div style="width:10em; float:left;"><img src="https://static.igem.org/mediawiki/2014/0/07/VUPVTeam_logo.png" width="100px"></div>
-
<li>
+
            <div style="float:left; padding-top:15px;"><h2>Valencia_UPV</h2></div>
-
    <a href="#" data-title="Manchester" data-description="Collaboration Meeting
+
            <div style="margin-top:8em;">
-
23rd July 2014
+
                <p>To assess how good the Lab Notation we had developed was, we reached out to Team Valencia and asked if they would be interested in testing the notation for us according to the specific procedure we sent them. They were sent the notation key and 2 protocols written in the standardized lab notation format. The titles of the protocols were not included in this pack to ensure that the volunteers were only using the information provided to them. They were then asked to fill in a qualitative review assessing how they had found carrying out each of the protocols . The  information obtained in the review and Team Valencia’s suggestions were very beneficial for the final correction and testing the the new notation we developed.</p>
-
Sheffield: Sharan, Mustafa, Ben L and Erika
+
            </div>
-
Manchester: Catherine, James and Isobel
+
        </div>
-
 
+
    </body>
-
Conclusion
+
-
Very unclear and unhelpful; couldn’t tell if they were holding back on information or just didn’t know themselves
+
-
- Unlikely to collaborate
+
-
 
+
-
Wet labs and assays - very unclear, have emailed to ask for a clarification document
+
-
Making an E. coli to absorb glucose
+
-
Detects levels of CRP (I think)
+
-
Riboswitch to respond to high glucose concentrations
+
-
Constitutive promoter
+
-
Wanted to collaborate on a potential lipid uptake system; they have no part for this and sounded as though they wanted us to give them one as we mentioned lipid uptake as a potential development in the future for reuse/energy - not a likely option as we have no time or need with our new product
+
-
GFP used in the assays, checking riboswitch activity in response to glucose levels
+
-
 
+
-
Modelling - biological modelling of effects on cell, not useful
+
-
 
+
-
HP - don’t really understand what they are doing, didn’t make sense as the ideas don’t gel; might be holding back?
+
-
Did outreach at an open day; didn’t really say what and how they are using this
+
-
Impact report - interviewing professors and surgeons from med school, incorporating sociological theory, speaking to companies for product development (yoghurt/food implementation), analysing survey results - we flagged this as there was no ethics or consent, they are now making this online and will email the link
+
-
 
+
-
Tracks - health/medicine, food, policy and practices
+
-
">
+
-
<div class="imageHolder">
+
-
<img src="https://static.igem.org/mediawiki/2014/8/8f/SheffieldCollaboration1.jpg" width="200px" alt="img01"/>
+
-
        <div class="caption"><h1>iGEM Manchester Skype Meeting Minutes</h1><p></p></div>
+
-
        </div>
+
-
    </a>
+
-
</li>
+
-
<li>
+
-
                <a href="#" data-title="Valencia" data-description="Collaboration Meeting
+
-
25rd July 2014
+
-
Sheffield: Ben L
+
-
Valencia_UPV: Jose, Lucia, Alba?
+
-
 
+
-
Overall there was slight difficulties in communication, possibly due to language barrier but more likely due to glitchy skype. Agreed to continue further communication by email.
+
-
Explanation of the sheffield project, mainly overview of science (BioBricks, proteins created) and product design type stuff - very brief
+
-
Valencia explain their project: Creating plants which produce sexual pheromones to induce mating disruption in moth species, avoiding the damage caused by larvae.
+
-
Talked about science collaboration: Valencia seemed to think we would create bacteria that would be secreting lipids (and not lipase), was suggested that they synthesise a lipid and we catabolise it, agreed this would be pointless
+
-
Valencia did not know where they stood with regards to modelling
+
-
HP Collaboration would potentially be more fruitful - Valencia making a survey to distribute (possibly to farmers?), talked about the possibility of exchanging our surveys, survey should be produced by the end of the week
+
-
Valencia willing to collaborate on Laboratory Notation System, would create protocols for procedures in plant sciencey things.
+
-
 
+
-
">
+
-
<div class="imageHolder">
+
-
    <img src="https://static.igem.org/mediawiki/2014/f/f8/SheffieldCollaboration2.png" width="220px" alt="img01"/>
+
-
    <div class="caption"><h1>Valencia Skype Meeting Minutes</h1><p></p></div>
+
-
</div>
+
-
</a>
+
-
</li>
+
-
</ul>
+
-
+
-
<script src="https://2014.igem.org/Team:Sheffield/Template:grid.js?action=raw&ctype=text/javascript"></script>
+
-
<script>
+
-
$(function() {
+
-
Grid.init();
+
-
});
+
-
</script>
+
-
+
-
 
+
-
+
-
</body>
+
</html>
</html>

Latest revision as of 03:46, 18 October 2014

Collaboration

Meetups

During the course of the project we formed collaborative links with a number of different iGEM teams to further integrate Sheffield into the iGEM community and establish potential associations for future iGEM teams from Sheffield. We attended the Oxford iGEM Meet Up on Thursday, 19th June 2014 to meet with other iGEM teams from the UK and Ireland. This was a great day with interesting talks from guest speakers giving us insight into the project. Over a poster session we established links with other iGEM teams with whom we later collaborated. As it was early on in the project timeline, it was useful to see where projects were heading and also the variety of issues being tackled using synthetic biology.

We hosted our own meet up on Friday, 18th July 2014, a month after the previous meet up. We felt that this would be a great time for us to solidify and identify specific areas and ideas on which we could collaborate with other teams, as other teams had started their lab work by this point. We met with the teams from Kent, NRP-UEA-Norwich, Oxford and York. Firstly, we had presentations from two guest speakers from the University of Sheffield: Professor Phillip C. Wright (Head of Chemical and Biological Engineering) who spoke about the development of synthetic biology from an engineering perspective, and Robert Meckin (Doctoral Researcher, Science and Technology Studies) who gave an insight into human practices surrounding synthetic biology. An networking activity involving human bingo allowed us to find out more about each other before a poster session and followed by a more relaxed evening on the town. We had a great time hosting the teams and hope they did too! Below is a video to show a summary of the events that took place:

Edinburgh

During the course of the project we established contact and collaborative links with a number of different iGEM teams. For instance, with Team Edinburgh we were in touch regarding Human Practices. During skype meetings we discussed our HP project approaches and decided there how our inter-team collaboration would work. Team sheffield was interviewed by team edinburgh over a skype call regarding task management and role distribution within a team. On the other hand, we asked some questions about the different components of their HP work, so that we could incorporate them in the SocioBrick Registry of standard parts that we developed for iGEM. We considered the collaboration successful in that each team was able to get the necessary data from each other to carry on their individual work. We then had a chance to personally meet some members of team Edinburgh in the Young Synthetic Biology Conference in London which was a wonderful further learn about the work they had been invested in as a whole.

Oxford

The Oxford iGEM Team were one of the first teams we established collaborative links with after the meet-up they held in Oxford. When we held our own meet-up in Sheffield, our teams agreed that there was an overlap in the aims of our project.

Team Oxford were one of the first teams we established collaborative links with. After the University of Sheffield Meet-up organised by us, our teams felt their was an overlap in the way our teams worked and what we were addressing and therefore decided that if needed there were certain identified that we could definitely collaborate in. For instance in the beginning of the project our team was having trouble obtaining successful transformations of a certain promoter that we require and so asked if Oxford could try transforming it and see if they encountered the same problem. Oxford were very helpful and happy to do it. However, while this was taking place, our team troubleshooted what the problem had been.

Further down the line, Oxford started developing a stochastic modelling system. With that, they asked if we would be interested in giving them some info regarding the promoters we were testing with our lipase and copy number which we did to allow them to further improve their model.

Paris Bettencourt

The Paris Bettencourt iGEM team was a team we collaborated with in their efforts to build a synthetic biology community for iGEM teams. We have participated in their fortnightly newsletter with a sizeable number of other iGEM teams from around the world, updating the participating teams with our progress so far and answering the questions asked by other teams. The newsletter was particularly successful and helped the Sheffield team integrate into the iGEM community.

We also participated in the development of Paris Bettencourt’s MOOC (Massively Open Online Course), run on Genius online knowledge base website, on which we annotated some of the entries and hope to continue to edit in future.

Valencia_UPV

To assess how good the Lab Notation we had developed was, we reached out to Team Valencia and asked if they would be interested in testing the notation for us according to the specific procedure we sent them. They were sent the notation key and 2 protocols written in the standardized lab notation format. The titles of the protocols were not included in this pack to ensure that the volunteers were only using the information provided to them. They were then asked to fill in a qualitative review assessing how they had found carrying out each of the protocols . The information obtained in the review and Team Valencia’s suggestions were very beneficial for the final correction and testing the the new notation we developed.