Team:Sheffield

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          <h1>A SYNTHETIC BIOLOGY SOLUTION FOR<br>AN EVERYDAY PROBLEM</h1>
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<p>We have engineered E. coli to secrete fat and hair degrading enzymes to solve the problem of accumulations in sewer networks</p>
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          <div class="slide-btns">
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          <a class="startnow" href="https://2014.igem.org/Team:Sheffield/Project">VIEW MORE</a>
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          <h1>Manufacturing a workable solution</h1>
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<p>We have created an innovative undersink bioreactor unit to degrade fat waste before it has chance to form <em>fatbergs</em></p>
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          <div class="slide-btns">
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          <a class="startnow" href="https://2014.igem.org/Team:Sheffield/modelling">VIEW MORE</a>
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          <h1>NOTIONS OF RESPONSIBILTY</h1>
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<p>Who should be responsible for the maintenance of drains? Is it the responsibility of synthetic biologists to step in?</p>
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          <a class="startnow" href="https://2014.igem.org/Team:Sheffield/Notions">VIEW MORE</a>
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<h4><b>The Fatberglar: A small scale, semi-continuous bioreactor for the controlled release of FOG degrading enzymes</b></h4>
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<h5>Fats, oils and greases (FOGs) enter the national sewage system and accumulate, leading to blocked pipes, nicknamed “fatbergs”. There are currently over 200,000 major UK sewage blockages a year, of which 75% are caused by FOGs; tackling these blockages costs water companies millions of pounds every month.
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The biological project work focused on development of constructs that produce lipase and keratinase enzymes to degrade FOGs and hair. These constructs are designed to sit within a small, under-sink bioreactor that will produce and feed them into the waste system as the sink is drained.
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To shape the approach, there has been significant interaction with industry experts and the public to gauge where the responsibility lies for the maintenance of the damaged drains; awareness of synthetic biology has been raised alongside this. A novel method of characterising the policy and practices component of the iGEM competition is also presented here.</h5>
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        <div class="section1">&nbsp;&nbsp;
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<img src="https://static.igem.org/mediawiki/2014/4/4c/SheffieldLogo6.png" width="200px">&nbsp;&nbsp;
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<img src="https://static.igem.org/mediawiki/2014/0/0d/SheffieldLogo2.png" width="200px">&nbsp;&nbsp;
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<img src="https://static.igem.org/mediawiki/2014/5/5a/SheffieldLogo7.png" width="200px">&nbsp;&nbsp;
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<img src="https://static.igem.org/mediawiki/2014/1/1e/SheffieldLogo8.png" width="200px">&nbsp;&nbsp;
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<img src="https://static.igem.org/mediawiki/2014/a/a6/SheffieldLogo9.png" width="200px">&nbsp;&nbsp;<br>
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&nbsp;&nbsp;<img src="https://static.igem.org/mediawiki/2014/8/85/SheffieldLogo11.jpg" width="200px">&nbsp;&nbsp;
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<img src="https://static.igem.org/mediawiki/2014/c/c7/SheffieldLogo10.png" width="200px">&nbsp;&nbsp;
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<img src="https://static.igem.org/mediawiki/2014/f/f1/Bioline.png" width="200px">&nbsp;&nbsp;
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<img src="https://static.igem.org/mediawiki/2014/4/4e/SheffieldLogo3.png" width="200px">&nbsp;&nbsp;
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<img src="https://static.igem.org/mediawiki/2014/1/19/SheffieldLogo5.png" width="200px">
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Latest revision as of 03:44, 18 October 2014




  • A SYNTHETIC BIOLOGY SOLUTION FOR
    AN EVERYDAY PROBLEM

    We have engineered E. coli to secrete fat and hair degrading enzymes to solve the problem of accumulations in sewer networks

    VIEW MORE

  • Manufacturing a workable solution

    We have created an innovative undersink bioreactor unit to degrade fat waste before it has chance to form fatbergs

    VIEW MORE

  • NOTIONS OF RESPONSIBILTY

    Who should be responsible for the maintenance of drains? Is it the responsibility of synthetic biologists to step in?

    VIEW MORE

The Fatberglar: A small scale, semi-continuous bioreactor for the controlled release of FOG degrading enzymes

Fats, oils and greases (FOGs) enter the national sewage system and accumulate, leading to blocked pipes, nicknamed “fatbergs”. There are currently over 200,000 major UK sewage blockages a year, of which 75% are caused by FOGs; tackling these blockages costs water companies millions of pounds every month.

The biological project work focused on development of constructs that produce lipase and keratinase enzymes to degrade FOGs and hair. These constructs are designed to sit within a small, under-sink bioreactor that will produce and feed them into the waste system as the sink is drained.

To shape the approach, there has been significant interaction with industry experts and the public to gauge where the responsibility lies for the maintenance of the damaged drains; awareness of synthetic biology has been raised alongside this. A novel method of characterising the policy and practices component of the iGEM competition is also presented here.


                 
             

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