Team:INSA-Lyon/Project

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<p style="text-align:justify" > The INSA-Lyon team is developping an <i>E. coli</i>-based platform as an alternative depollution method for metal contamination in water using an amyloid-display system for surface-functionalization, called <b>CurLy'On</b>. As far as France is concerned, drinkable water contamination from the metal pipes is a real issue. Indeed, the cost is estimated to twenty billion euros to fully replace the existing infrastructure. Using our system based on nano-sponge surfaces for water purification, we propose to extend this concept into a cheap bacterial filter as a solution. Indeed, the use of surface-specific protein particularly benefits the biotechnology research field, and extensively the synthetic biology field, in depollution alternative strategies but also in the medical field by improving the dialysis’ filter specificty on various metals for renal-insufficient patients. </p>
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<p style="text-align:justify" > <b>The INSA-Lyon team is developing an <i>E. coli</i>-based platform as an alternative depollution method for metal contamination </b> in water using an amyloid-display system for surface-functionalization, called <b>CurLy'on</b>. As far as France is concerned, drinkable water contamination from the metal pipes is a real issue. Indeed, the cost is estimated to twenty billion euros to fully replace the existing infrastructure. Using our system based on nano-sponge surfaces for water purification, we propose to extend the <b>CurLy'on</b> concept into a cheap bacterial filter as a solution. The use of surface-specific proteins particularly benefits the biotechnology research field in depollution alternative strategies but also in the medical field by improving the dialysis’ filter specificity on various metals for renal-insufficient patients. </p>
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<b>Unlike most metal bioremediation projects, our solution does not rely on intracellular capture, which means we can kill the bacteria and degrade their DNA using physio-chemical methods to ensure the safety of the biofilter</b>
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<a style="margin-left:320px" href="http://www.dailymotion.com/video/x26w54u_curly-on-presentation-igem-insa-lyon-2014_tech" target="_blank">CurLy&#039;on Presentation - iGEM INSA-Lyon 2014</a> <i>par
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<a style="color:black" href="http://www.dailymotion.com/iGEM_Lyon_2011" target="_blank">iGEM_Lyon_2014</a></i>
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    <source src="http://potopov.fr/igem/presentation.mp4" />
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<a style="margin-left:250px" href="http://www.dailymotion.com/video/x26w54u_curly-on-presentation-igem-insa-lyon-2014_tech" target="_blank">CurLy&#039;on Presentation - iGEM INSA-Lyon 2014</a> <i>
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<a style="color:black" href="http://www.dailymotion.com/iGEM_Lyon_2011" target="_blank"></a></i>
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Latest revision as of 03:02, 18 October 2014

Curly'on - IGEM 2014 INSA-LYON

IGEM

PROJECT SUMMARY

The INSA-Lyon team is developing an E. coli-based platform as an alternative depollution method for metal contamination in water using an amyloid-display system for surface-functionalization, called CurLy'on. As far as France is concerned, drinkable water contamination from the metal pipes is a real issue. Indeed, the cost is estimated to twenty billion euros to fully replace the existing infrastructure. Using our system based on nano-sponge surfaces for water purification, we propose to extend the CurLy'on concept into a cheap bacterial filter as a solution. The use of surface-specific proteins particularly benefits the biotechnology research field in depollution alternative strategies but also in the medical field by improving the dialysis’ filter specificity on various metals for renal-insufficient patients.

Unlike most metal bioremediation projects, our solution does not rely on intracellular capture, which means we can kill the bacteria and degrade their DNA using physio-chemical methods to ensure the safety of the biofilter

CurLy'on Presentation - iGEM INSA-Lyon 2014

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