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Team:Tsinghua-A
From 2014.igem.org
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| + | <h2> Introduction </h2> | ||
| + | <h3>Transactivator-Like Effectors (TALEs) are a technology that once revolutionized the way researchers manipulate DNA with exceptional site specificity.Though it works well in eukaryotic organisms, it is not available in prokaryotic organisms. We come up with the idea that the long repeating sequence of the TALEs coding sequence leads to it. In our project, we attempt to construct a marvelous TALEs system which can efficiently work in prokaryotic organisms. By optimizing the TALEs coding sequence with modeling methods and testing it by Golden Gate Assembly and Report System, we hope we can have a handle tool for gene editing in prokaryotic organisms. | ||
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| + | <img src="https://static.igem.org/mediawiki/2014/0/08/Tsinghua-A_Wishtobethefinal.jpg"> | ||
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<div class="span3 text-center service-box"> | <div class="span3 text-center service-box"> | ||
<a href="https://2014.igem.org/Team:Tsinghua-A/Project"> | <a href="https://2014.igem.org/Team:Tsinghua-A/Project"> | ||
| - | <img class="team-thumb img-circle" src="https://static.igem.org/mediawiki/ | + | <img class="team-thumb img-circle" src="https://static.igem.org/mediawiki/2014/5/57/Tsinghua-A-project.jpg" alt=""> |
<h2>Project</h2> | <h2>Project</h2> | ||
| - | <p> | + | <p>Background, hypothesis and workflow of designer TALE. </p> |
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<a href="https://2014.igem.org/Team:Tsinghua-A/Modeling"> | <a href="https://2014.igem.org/Team:Tsinghua-A/Modeling"> | ||
| - | <img class="team-thumb img-circle" src="https://static.igem.org/mediawiki/ | + | <img class="team-thumb img-circle" src="https://static.igem.org/mediawiki/2014/2/24/Tsinghua-A-modeling3.jpg" alt=""> |
<h2>Modeling</h2> | <h2>Modeling</h2> | ||
| - | <p> | + | <p>Optimization of TALE sequence and simulation of the gene circuit. </p> |
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<a href="https://2014.igem.org/Team:Tsinghua-A/HumanPractice"> | <a href="https://2014.igem.org/Team:Tsinghua-A/HumanPractice"> | ||
| - | <img class="team-thumb img-circle" src="https://static.igem.org/mediawiki/ | + | <img class="team-thumb img-circle" src="https://static.igem.org/mediawiki/2014/c/c9/Tsinghua-A_HP.jpg" alt=""> |
| - | <h2> Human Practice</h2> | + | <h2>Human Practice</h2> |
| - | <p> | + | <p>Lectures, seminar, questionnaires and raising ethic problems. </p> |
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<a href="https://2014.igem.org/Team:Tsinghua-A/Team"> | <a href="https://2014.igem.org/Team:Tsinghua-A/Team"> | ||
| - | <img class="team-thumb img-circle" src="https://static.igem.org/mediawiki/ | + | <img class="team-thumb img-circle" src="https://static.igem.org/mediawiki/2014/8/8e/Tsinghua-A_team.jpg" alt=""> |
<h2>Team</h2> | <h2>Team</h2> | ||
| - | <p> | + | <p>Department of Automatics, Life Science and Medical School. </p> |
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| + | <h2> Team </h2> | ||
| + | <img src="https://static.igem.org/mediawiki/2014/7/70/Tsinghua-A_team.png" alt="Title"> | ||
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<h2> Acknowledgements </h2> | <h2> Acknowledgements </h2> | ||
| - | <img src="https://static.igem.org/mediawiki/2014/4/45/Tsinghua-A_acc.png" alt="Title"> | + | <img src="https://static.igem.org/mediawiki/2014/4/45/Tsinghua-A_acc.png" alt="Title"> |
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Latest revision as of 03:01, 18 October 2014
Introduction
Transactivator-Like Effectors (TALEs) are a technology that once revolutionized the way researchers manipulate DNA with exceptional site specificity.Though it works well in eukaryotic organisms, it is not available in prokaryotic organisms. We come up with the idea that the long repeating sequence of the TALEs coding sequence leads to it. In our project, we attempt to construct a marvelous TALEs system which can efficiently work in prokaryotic organisms. By optimizing the TALEs coding sequence with modeling methods and testing it by Golden Gate Assembly and Report System, we hope we can have a handle tool for gene editing in prokaryotic organisms.
Team
Acknowledgements
