Team:York

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<li class="active"><a href="https://2014.igem.org/Team:York">Home</a></li>
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                                                <a href="#" class="dropdown-toggle" data-toggle="dropdown">Project
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                                                        <li><a href="https://2014.igem.org/Team:York/Project">The Challenge</a></li>
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                                                        <li><a href="https://2014.igem.org/Team:York/Constructs">The Solution</a></li>
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                                                        <li><a href="https://2014.igem.org/Team:York/Application">Future Applications</a></li>
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                                                <a href="#" class="dropdown-toggle" data-toggle="dropdown">Achievements
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                                                        <li><a href="https://2014.igem.org/Team:York/Judging">Judging Criteria</a></li>
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                                                        <li><a href="https://2014.igem.org/Team:York/Results">Results</a></li>
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                                                        <li><a href="https://2014.igem.org/Team:York/Parts">Parts</a></li>
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<a href="#" class="dropdown-toggle" data-toggle="dropdown">Policy And Practice
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                                                        <li><a href="https://2014.igem.org/Team:York/Environment">Environmental Impact</a></li>
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<li><a href="https://2014.igem.org/Team:York/Surveys">Survey and GMOs</a></li>
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<li> <a href="https://2014.igem.org/Team:York/Outreach">Outreach</a></li>
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<h2>To celebrate iGEM’s 10 Anniversary and the upcoming Giant Jamboree we, the University of York team, wanted to focus on a global problem that affects millions of people in the world. Inspired by the ecological disaster of Portman Bay, Spain that lead to the release of up to 50 million tons of mining tailings into the Mediterranean Sea over 30 years, we aim to develop an effective treatment for the waste produced by the mining industry that has already been released.  
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<a href="#" class="dropdown-toggle" data-toggle="dropdown">Notebook
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We have found sulfates and heavy metals such as cadmium to be the most abundant and problematic compounds in the affected areas. The goal of our project is to engineer a strain of Escherichia coli to produce phytochelatins -binding metal peptides produced by plants, yeasts and others- in a metal-sensitive way to sequester the metal ions. In order to do so we plan to overexpress modified versions of endogenous E. coli enzymes that will enhance the yield of phytochelatins as well as the uptake of sulfates and the metals in question.  
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We will work on parts already present in the library and submit new ones both natural and synthetic ones contribution this way to improve the BioBricks catalogue. Moreover, the University of York 2014 team could be the first stone for a toolkit for targeting and sequestering specific metals in soil in a bioremediation context.  
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<a href="https://2014.igem.org/Team:York/Team">Students and Instructors</a></li>
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<li><a href="https://2014.igem.org/Team:York/Sponsors">Sponsors and Attributions</a></li>
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<p style="font-size:150%">Our project <i>EcoCADMUS</i> (<i>E. Coli</i> CAdmium DecontaMination Universal System)
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aims to provide a safe and effective way to remove Cadmium and Sulfate from wastewater.</p>
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<a href="https://2014.igem.org/Team:York/Project">
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<h2>The Solution</h2>
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<p style="font-size:150%">Our project is a biological approach to solving an environmental problem; the removal of cadmium and sulfate from waste water. Our aim is to increase cadmium and sulfate uptake in our chassis, <i>E.coli</i>. Our system involves chelating cadmium intra-cellularly through over-expressing cysteine-rich phytochelatins. Find out more about our project here.</p><br>
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<h2>Our Achievements</h2>
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<p style="font-size:150%">We have been working hard over summer in the labs to create our constructs. Click here to find out more about the characterisation of our constructs!</p><br>
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<h2>Outreach</h2>
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<p style="font-size:150%">As part of our project, we wanted to introduce the public to the concept of Genetically Modified Organisms and how they have a multitude of uses. Our outreach took us to many people and places as we explored the relationship between the public and Synthetic Biology</p><br>
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<h2>The Team</h2>
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<p style="font-size:150%">Our team is comprised of 19 undergraduates from the University of York. Find out more about the team and the people who supported us throughout this year.</p><br>
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<h2>Hello! We're from the
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<p><b>Our project <i>EcoCADMUS</i> (E. Coli CAdmium DecontaMination Universal System)
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aims to provide a safe and effective way to remove Cadmium and Sulfate from wastewater.</p>
 +
                <a href="https://2014.igem.org/Team:York/Project"<b>>
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                    <button type="button" class="btn btn-primary">Learn More!</button>
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            <div class="panel-heading"><h3>Our Team</h3></div>
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            <img class="img-responsive" src="https://static.igem.org/mediawiki/2014/4/44/York_TeamHomePage.jpg">
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            <p>Come and meet our lovely team!<br>We've been working hard (mostly!) on our project all over Summer.</p>
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                <a href="https://2014.igem.org/Team:York/Team">
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                    <button type="button" class="btn btn-primary">Meet the Team!</button>
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            <div class="panel-heading"><h3>Our final Construct</h3></div>
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                <img class="img-responsive" src="https://static.igem.org/mediawiki/2014/a/ae/York_Constructs.jpg">
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                <p>To find our more about our final construct we have designed.</p>
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                <a href="https://2014.igem.org/Team:York/Constructs">
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            <img class="img-responsive" src="https://static.igem.org/mediawiki/2014/7/7d/York_Researchhomepage.jpg">
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            <p>We have been busy communicating Synthetic Biology and contemplating the sustainability and ethics of our project. </p>
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                <a href="https://2014.igem.org/Team:York/SocialImpacts">
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                    <button type="button" class="btn btn-primary">Read our Report</button>
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Latest revision as of 02:47, 18 October 2014

Team York 2014



Hello! We're from the

Our project EcoCADMUS (E. Coli CAdmium DecontaMination Universal System) aims to provide a safe and effective way to remove Cadmium and Sulfate from wastewater.

>


Our Team

Come and meet our lovely team!
We've been working hard (mostly!) on our project all over Summer.

Our final Construct

To find our more about our final construct we have designed.

Social Outreach

We have been busy communicating Synthetic Biology and contemplating the sustainability and ethics of our project.

Retrieved from "http://2014.igem.org/Team:York"