Team:SCUT/HP/Magazine/iGEM Bilingualism

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The Delegates of SCUT Team Went to Wuhan for iGEMers’Meetup
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清凉夏夜，送你一支荧光雪糕<br>The Amazing Fluoresce Ice Cream
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On 23th Aug. 2014, the first central china iGEMers’meetup held by the union of Central China iGEM Teams was solemnly opened. This meeting attracts 16 iGEM teams from 17 universities，and SCUT team also sent two delegates to Wuhan to communicate. One was our team leader, Zhang Junjie, and the other was the head of HP part, Wang Zhizheng.
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British boutique ice cream maker Lick Me I'm Delicious (yes, that is the company's real name) recently released a glow-in-the-dark ice cream that uses a luminescent protein from glowing jellyfish. The idea? Lick the ice cream and calcium-activated proteins react by glowing, thanks to differences in your mouth's warmer pH level and the ice cream's more neutral pH.
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The meeting lasting 2 days was organized by HZAU, WHU and HUST iGEM teams. The contents consisted of three main parts: senior iGEMers’ reports, project presentation by each team, and the discussion of debugs in experiments. On the morning of 23th  August, Dr. Tang Jun, the professor of HZAU participated in the opening ceremony and gave a welcoming speech. Then we watched the video made by the chairman iGEM Head Quarters specially for the meeting. It was really helpful and wonderful. After the opening ceremony, the seniors Zhang Haoqian and Liu Yang coming from Peking University and Ocean University of China gave us two important speeches, sharing their abundant experience about iGEM. It really paid to learn.
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英国精品雪糕制造商Lick Me I'm Delicious(舔我~我超好吃的哦~ ~(≧▽≦)/~)上市了一款能在黑暗中发光的雪糕。这款雪糕中添加了取自发光水母的发光蛋白，此外，我们的唾液成弱碱性，在舔雪糕的时候，使pH值升高，从而使钙激活蛋白发光。在你舔雪糕的时候，你就会发现雪糕越来越亮啦！（好神奇有木有！）
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(pic 1 Haoqian was sharing his iGEM life.)
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Be forewarned: a scoop will set you back about $220 in sweet change. Turns out jellyfish protein isn't exactly cheap. But no worries: Charlie Harry Francis, the food scientist who invented the treat, assures foodies that it's safe for consumption.
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要提醒大家的是，你需要花费220刀才能吃到这种发光的甜甜的雪糕球，因为提取水母蛋白的成本很高。另外，我们也不必担心食品安全问题，食品科学专家Charlie Harry Francis，同时也是荧光雪糕的发明者，已经确定这种雪糕对消费者来说百分之百安全。
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At first, Zhang Haoqian made a report and talked with us on five aspects. The contents were as follows: his experiences of joining in iGEM, the development of iGEM, the judging standards and some helpful tips, meanwhile he also told us the problems we faced about synthetic biology and introduced his research about synthetic biology. After that, Liu Yang raised a heated discussion with us. He asked us whether we should be guided by the application or research while we are designing our projects. Different people held different opinions. The atmosphere of discussion was pretty good. And we were so grateful for their detailed and impressive speeches.
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The glowing frozen dessert made us wonder about other instances of luminescence out there. Green fluorescent proteins used in studies aren't just the stuff of mad scientist dreams: it earned the inventor glowing praise and a Nobel Prize in 2008.  
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这种冷光蛋白也不仅仅只是用于制作酷炫雪糕。绿色荧光蛋白应用于科研邻域早就不是痴人说梦，荧光蛋白的发现者和改造者赢得了2008年的诺贝尔奖。
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(Pic 2 Liu Yang was explaining a research)
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Now fluorescent proteins have been already widely used in many scientific research fields, especially in biology. In iGEM, fluorescent proteins are usually used as reporters. What are reporters? The answer is that in synthetic biology, they are often used as a mechanism to display information. For example, fluorescent proteins cause a cell to fluoresce when excited with light of a particular wavelength. What’s more, the iGEM team of Tokyo Tech once used fluorescent proteins to create a pen whose ink is the different genetically engineered bacteria. The bacteria can express different fluorescent proteins so that people can use it to draw many colorful paintings.
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During the break of the meting, there were a variety of drinks and snacks in the lounge. We talked with friends as we drank coffee and ate cakes, which was so relaxing. Meanwhile there was also a poster area where we can see the posters of different teams to learn their ideas and thoughts. The posters all have their own features of their team, for example, the poster of Ocean University of China was painted on a blue background just like the beautiful ocean.
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In the afternoon, HUST team and other 6 teams presented their projects in English. At first, two girls of HUST team introduced their project and they designed an engineering bacterium called Cao Mengde that can monitor Cu2+ of effluent, and meanwhile adsorb cyanogen compounds. And BNU team designed a project about an enzyme called ModA. The enzyme can adsorb and fix nitrogen and release molybdenum, which is of great help for plants to grow. And CAU team also bring us an amazing project. They tried to use a certain mechanism to make the engineering bacteria express RFP cyclically so that make a snowflake-shaped picture.WHU-Pharm team focused on designing a drug monitor without cellular system,while  Jinlin team chose a project of environment track just like Peking team in order to control water pollution. 
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如今，荧光蛋白已经广泛用于科学研究的各个领域，尤其是生物学领域。在iGEM中，荧光蛋白常常用作报告指示器（reporter）。什么是reporter？在合成生物学中，reporter就是可以直观显示信息的一种机制。例如，在特定波长的光的激发下，荧光蛋白就会使其所在细胞发出荧光，从而能起到定位指示的作用。除此之外，东京工业大学的iGEM队伍曾经利用不同的荧光蛋白，将其基因导入工程细菌中，从而设计并制造出了一支细菌荧光笔，并且画出一些彩色的图画，从而使荧光蛋白第一次应用到了艺术领域，可谓独具匠心。
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(Pic 3 Our delicious dinner)
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（上图中，从a-f依次为黄色、蓝色、绿色、橘黄色、红色以及红黄绿三色混合起来的荧光蛋白。）
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At dinner, HZAU team brought us a sumptuous feast. We tasted various delicious local foods in Zhuyuan Dining Hall. After dinner, we had a lively and amazing discussion, which we called free talk. We have deep-going discussion and communication with BIT team, NDTU team, LZU team, WHU team and AHUT team. The atmosphere of free talk cannot be more enthusiastic, and all members have a very positive attitude to talk with their new friends and other team members. We cannot help being moved by our enthusiasm.  
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Reporters are frequently used to quantify the strength or activity of upstream gene expression parts. Reporters, when fused in frame to other protein coding sequences, can also be used to identify where a protein is located in a cell or organism, which is fully reflected in this year’s project of Team SCUT. Our Team will use the cherry，yellow，blue，green and cyan fluorescent proteins to indicate whether our target proteins reach the right positions of the cell.
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All team members made great efforts for one topic, one dream and one goal. We encouraged each other, and we were grateful for HZAU held the wonderful meet-up, which we cannot forget any more. What’s more, one of our team delegates also found a fellow-townsman in this competition, which made him feel very warm and happy.
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Reporters常用于测定上游基因原件的表达强度或是活性，当reporters和其他蛋白融合在一起时，可以用于确定蛋白在细胞或是组织中的位置。这一作用在今年我们SCUT队伍的项目中有充分的体现。我们将利用红色、黄色、蓝色、绿色以及蓝绿色的荧光蛋白去指示到底我们的目标蛋白有没有到达细胞中的正确位置上。
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All in all, the most important meaning of joining in iGEM is not about the grade , and should be the knowledge, confidence, friendship and the beautiful memory!
 
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(Pic 4 The group photo with WHU iGEMers)
 
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Latest revision as of 00:18, 18 October 2014

清凉夏夜，送你一支荧光雪糕
The Amazing Fluoresce Ice Cream

British boutique ice cream maker Lick Me I'm Delicious (yes, that is the company's real name) recently released a glow-in-the-dark ice cream that uses a luminescent protein from glowing jellyfish. The idea? Lick the ice cream and calcium-activated proteins react by glowing, thanks to differences in your mouth's warmer pH level and the ice cream's more neutral pH.

英国精品雪糕制造商Lick Me I'm Delicious(舔我~我超好吃的哦~ ~(≧▽≦)/~)上市了一款能在黑暗中发光的雪糕。这款雪糕中添加了取自发光水母的发光蛋白，此外，我们的唾液成弱碱性，在舔雪糕的时候，使pH值升高，从而使钙激活蛋白发光。在你舔雪糕的时候，你就会发现雪糕越来越亮啦！（好神奇有木有！）

Be forewarned: a scoop will set you back about $220 in sweet change. Turns out jellyfish protein isn't exactly cheap. But no worries: Charlie Harry Francis, the food scientist who invented the treat, assures foodies that it's safe for consumption. 要提醒大家的是，你需要花费220刀才能吃到这种发光的甜甜的雪糕球，因为提取水母蛋白的成本很高。另外，我们也不必担心食品安全问题，食品科学专家Charlie Harry Francis，同时也是荧光雪糕的发明者，已经确定这种雪糕对消费者来说百分之百安全。

The glowing frozen dessert made us wonder about other instances of luminescence out there. Green fluorescent proteins used in studies aren't just the stuff of mad scientist dreams: it earned the inventor glowing praise and a Nobel Prize in 2008. 这种冷光蛋白也不仅仅只是用于制作酷炫雪糕。绿色荧光蛋白应用于科研邻域早就不是痴人说梦，荧光蛋白的发现者和改造者赢得了2008年的诺贝尔奖。

Now fluorescent proteins have been already widely used in many scientific research fields, especially in biology. In iGEM, fluorescent proteins are usually used as reporters. What are reporters? The answer is that in synthetic biology, they are often used as a mechanism to display information. For example, fluorescent proteins cause a cell to fluoresce when excited with light of a particular wavelength. What’s more, the iGEM team of Tokyo Tech once used fluorescent proteins to create a pen whose ink is the different genetically engineered bacteria. The bacteria can express different fluorescent proteins so that people can use it to draw many colorful paintings.

如今，荧光蛋白已经广泛用于科学研究的各个领域，尤其是生物学领域。在iGEM中，荧光蛋白常常用作报告指示器（reporter）。什么是reporter？在合成生物学中，reporter就是可以直观显示信息的一种机制。例如，在特定波长的光的激发下，荧光蛋白就会使其所在细胞发出荧光，从而能起到定位指示的作用。除此之外，东京工业大学的iGEM队伍曾经利用不同的荧光蛋白，将其基因导入工程细菌中，从而设计并制造出了一支细菌荧光笔，并且画出一些彩色的图画，从而使荧光蛋白第一次应用到了艺术领域，可谓独具匠心。

（上图中，从a-f依次为黄色、蓝色、绿色、橘黄色、红色以及红黄绿三色混合起来的荧光蛋白。）

Reporters are frequently used to quantify the strength or activity of upstream gene expression parts. Reporters, when fused in frame to other protein coding sequences, can also be used to identify where a protein is located in a cell or organism, which is fully reflected in this year’s project of Team SCUT. Our Team will use the cherry，yellow，blue，green and cyan fluorescent proteins to indicate whether our target proteins reach the right positions of the cell.

Reporters常用于测定上游基因原件的表达强度或是活性，当reporters和其他蛋白融合在一起时，可以用于确定蛋白在细胞或是组织中的位置。这一作用在今年我们SCUT队伍的项目中有充分的体现。我们将利用红色、黄色、蓝色、绿色以及蓝绿色的荧光蛋白去指示到底我们的目标蛋白有没有到达细胞中的正确位置上。

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