Team:Georgia State
From 2014.igem.org
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<h4>Transforming Linearized Mambalgin into <i>P. pastoris</i></h4> | <h4>Transforming Linearized Mambalgin into <i>P. pastoris</i></h4> | ||
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<p><a href="https://2014.igem.org/Team:Georgia_State/Project_Summary/">Read more...</a></p> | <p><a href="https://2014.igem.org/Team:Georgia_State/Project_Summary/">Read more...</a></p> | ||
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<p><a href="https://2014.igem.org/Team:Georgia_State/Project_Summary/">Read more...</a></p> | <p><a href="https://2014.igem.org/Team:Georgia_State/Project_Summary/">Read more...</a></p> | ||
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Revision as of 23:56, 17 October 2014
Building an Expression Vector
Transforming Linearized Mambalgin into P. pastoris
Mambalgin Synthesis
The Applications
Our research is far reaching and has the potential to completely transform the medical industry with non-addictive pain management.
Mamba: An entry into iGEM 2014
Our team from Georgia State University has been working to successfully insert and purify mambalgin, a protein component of the venom of Dendroaspis Polylepis, better known as the Black Mamba. The mambalgin peptide is a powerful analgesic that directly blocks pain transmission in the peripheral nervous system (Diochot et al, 2012) by targeting acid sensing ion channels within nociceptors beneath the epidermis. Furthermore, recombinant purification of mambalgin could assist in developing anti-venom without the attendant risk of harvesting venom directly from snakes.
From the Lab
Video Highlights