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Team:UT-Tokyo
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<h2>Our Team</h2> | <h2>Our Team</h2> | ||
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| + | <a href="https://igem.org/Team.cgi?id=1461" target="_blank"><img src = "https://static.igem.org/mediawiki/2014/f/f8/Team_icon_ut.png" class = "sns" onMouseover="this.src='https://static.igem.org/mediawiki/2014/0/05/Team_iconon.png'" onMouseout="this.src='https://static.igem.org/mediawiki/2014/f/f8/Team_icon_ut.png'"></a> | ||
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Revision as of 18:44, 17 October 2014
Project Description
In the field of synthetic biology, Genetic memory devices have been constructed and applied widely from Biocomputing to biomedical technologies as a crucial component. Such memory devices include a cellular counter; a fundamental device which memorizes the number of induction events. Recent efforts have resulted in a cellular counter that can count up to three events. However, this counter cannot be reset to its initial state. Here, we propose a resettable cellular counter called “sigma recounter”. This counter utilizes the regulation system of sigma factor and anti-sigma factor as the key of its resetting mechanism. In this system a set of sigma factors are designed to update and maintain a count that responds to each inducted event. By the other stimulus, the system initiates a genetic circuit that can express a suitable set of anti-sigma factors and erases the existing memory, which will enable our device to restart the count from any state.
Our Team
Address
7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8654 Japan
