Team:Oxford/biosensor
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Biological systems are very good at sensing the huge range of chemical and physical inputs in the world around them, often at very low levels. They need to do this in order to respond to and survive the constant changes in their environment. In many cases, this sensing results in a change at the transcriptional level in the organism. For example, Methylobacterium extorquens DM4 increases expression of DCM dehalogenase in the presence of DCM in order to exploit this carbon source. This means we can use these natural sensing systems to engineer novel genetic circuits that will respond to specific inputs with detectable outputs; in other words, to create a biosensor. <br><br> | Biological systems are very good at sensing the huge range of chemical and physical inputs in the world around them, often at very low levels. They need to do this in order to respond to and survive the constant changes in their environment. In many cases, this sensing results in a change at the transcriptional level in the organism. For example, Methylobacterium extorquens DM4 increases expression of DCM dehalogenase in the presence of DCM in order to exploit this carbon source. This means we can use these natural sensing systems to engineer novel genetic circuits that will respond to specific inputs with detectable outputs; in other words, to create a biosensor. <br><br> | ||
- | <img src="https://static.igem.org/mediawiki/2014/6/68/Oxford_Biosensor_homepage_realisation.png" style="float:right;position:relative;width: | + | <img src="https://static.igem.org/mediawiki/2014/6/68/Oxford_Biosensor_homepage_realisation.png" style="float:right;position:relative;width:250px;margin-bottom:10px;"/> |
<h1>Optimising our Design</h1> | <h1>Optimising our Design</h1> | ||
Revision as of 17:57, 17 October 2014