Team:Purdue

From 2014.igem.org

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<h1><span></html>Project Overview<html></span></h1>
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</html>More than 870 million people are malnourished according to the United Nations World Food Program, and the World Health Organization states that iron deficiency is one of the most common and widespread nutritional disorders in the world. A solution is presented by utilizing synthetic biology to engineer Bacillus subtilis to increase plants’ ability to uptake iron, through production of plant phytosiderophores. Phytosiderophores are small, high-affinity iron chelating molecules that many microorganisms and plants use to increase bioavailable iron by reducing Fe3+ to Fe2+. Our genetically engineered system combines five corn genes to produce these phytosiderophores: SAMS, NAS1, NAATI, DMAS, and TOM1. We are using corn and rice to confirm that plants grown with our engineered bacteria will have higher iron content than plants grown with wild-type Bacillus or with no Bacillus at all. Chlorophyll readings and height measurements were used to determine the effectiveness of our engineered system.
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<a href="https://2014.igem.org/Team:Purdue"style="color:#000000">Home </a> </td>
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<a href="https://2014.igem.org/Team:Purdue/Team"style="color:#000000"> Team </a> </td>
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<a href="https://igem.org/Team.cgi?year=2014&team_name=Purdue"style="color:#000000"> Official Team Profile </a></td>
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<a href="https://2014.igem.org/Team:Purdue/Project"style="color:#000000"> Project</a></td>
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<a href="https://2014.igem.org/Team:Purdue/Parts"style="color:#000000"> Parts</a></td>
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<a href="https://2014.igem.org/Team:Purdue/Modeling"style="color:#000000"> Modeling</a></td>
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<a href="https://2014.igem.org/Team:Purdue/Safety"style=" color:#000000"> Safety </a></td>
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<a href="https://2014.igem.org/Team:Purdue/Attributions"style="color:#000000"> Attributions </a></td>
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<p> Please be sure to keep these links, your audience will want to find your: </p>
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<li><a href="https://2014.igem.org/Team:Purdue">Home</a> </li>
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<li><a href="https://2014.igem.org/Team:Purdue/Team">Team</a> </li>
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<li><a href="https://igem.org/Team.cgi?year=2013&team_name=Purdue">Official Team Profile</a> </li>
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<li><a href="https://2014.igem.org/Team:Purdue/Project">Project</a> </li>
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<li><a href="https://2014.igem.org/Team:Purdue/Parts">Parts</a> </li>
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<li><a href="https://2014.igem.org/Team:Purdue/Modeling">Modeling</a> </li>
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<li><a href="https://2014.igem.org/Team:Purdue/Safety">Safety</a> </li>
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<li>As part of your documentation, keep the links from the menu to the left. </li>
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<li>The <a href="https://static.igem.org/mediawiki/igem.org/6/60/Igemlogo_300px.png"> iGEM logo </a> should be placed on the upper part of every page and should link to <a href="https://2014.igem.org/Main_Page">2014.igem.org</a>.</li>
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<p>Visit the <a href="https://2014.igem.org/Wiki_How-To"> Wiki How To page </a> for a complete list of requirements, tips and other useful information. </p>
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<p>We are currently working on providing teams with some easy to use design templates.
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<br> In the meantime you can also view other team wikis for inspiration! Here are some very good examples</p>
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<li> <a href="https://2013.igem.org/Team:SDU-Denmark/"> 2013 SDU Denmark </a> </li>
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<li> <a href="https://2013.igem.org/Team:SYSU-China">2013 SYSU China</a> </li>
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<li> <a href="https://2013.igem.org/Team:Shenzhen_BGIC_ATCG"> 2013 Shenxhen BGIG ATCG </a></li>
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<li> <a href="https://2013.igem.org/Team:Colombia_Uniandes">2013 Colombia Unianades </a></li>
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<p>For a full wiki list, you can visit <a href="https://igem.org/Team_Wikis?year=2013">iGEM 2013 web sites </a> and <a href="https://igem.org/Team_Wikis?year=2012">iGEM 2012 web sites</a>  lists. </p>
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<p>This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started: </p>
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<li>You have a global audience! Consider the different backgrounds that your users come from.</li>
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<li>Make sure information is easy to find; nothing should be more than 3 clicks away.  </li>
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<li>Avoid using very small fonts and low contrast colors; information should be easy to read.  </li>
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<li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="">iGEM 2013 calendar</a> </li>
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<li>Have lots of fun! </li>
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Revision as of 03:49, 17 October 2014

Project Overview

More than 870 million people are malnourished according to the United Nations World Food Program, and the World Health Organization states that iron deficiency is one of the most common and widespread nutritional disorders in the world. A solution is presented by utilizing synthetic biology to engineer Bacillus subtilis to increase plants’ ability to uptake iron, through production of plant phytosiderophores. Phytosiderophores are small, high-affinity iron chelating molecules that many microorganisms and plants use to increase bioavailable iron by reducing Fe3+ to Fe2+. Our genetically engineered system combines five corn genes to produce these phytosiderophores: SAMS, NAS1, NAATI, DMAS, and TOM1. We are using corn and rice to confirm that plants grown with our engineered bacteria will have higher iron content than plants grown with wild-type Bacillus or with no Bacillus at all. Chlorophyll readings and height measurements were used to determine the effectiveness of our engineered system.

Retrieved from "http://2014.igem.org/Team:Purdue"