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Team:Tuebingen
From 2014.igem.org
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| - | <h1>Tuebingen Erythrocyte Conversion to O | + | <h1>Tuebingen Erythrocyte Conversion to O</h1> |
<h4>Welcome to the Wiki of Team Tuebingen!</h4> | <h4>Welcome to the Wiki of Team Tuebingen!</h4> | ||
| - | <p>This year, our project was all about blood and blood transfusions. You might not have known but donor blood is a really rare resource - not only in hospitals in countries with weak medical infrastructure or in crisis regions after natural disasters but also in ordinary Central European hospitals. Due to the fact that humans have at least four different blood groups and two different Rhesus factors - all antigens on erythrocytes - you cannot simply transfuse any blood you want to any random patient. Thus, hospitals do need to always keep an eye on their stocks lest they they are hit by shortages.</p> | + | <p>This year, our project - Tuebingen Erythrocyte Conversion to O (T-ECO) - was all about blood and blood transfusions. You might not have known but donor blood is a really rare resource - not only in hospitals in countries with weak medical infrastructure or in crisis regions after natural disasters but also in ordinary Central European hospitals. Due to the fact that humans have at least four different blood groups and two different Rhesus factors - all antigens on erythrocytes - you cannot simply transfuse any blood you want to any random patient. Thus, hospitals do need to always keep an eye on their stocks lest they they are hit by shortages.</p> |
<p>Therefore, we decided to create a practical and easy to use system for the enzymatic conversion of blood types - from blood types A, B and AB to O. Blood type O consists of erythrocytes that do not show any blood type antigens thus can be transfered to any patient and is usually used as emergency donor blood for exactly this reason.</p> | <p>Therefore, we decided to create a practical and easy to use system for the enzymatic conversion of blood types - from blood types A, B and AB to O. Blood type O consists of erythrocytes that do not show any blood type antigens thus can be transfered to any patient and is usually used as emergency donor blood for exactly this reason.</p> | ||
Revision as of 20:01, 16 October 2014
Tuebingen Erythrocyte Conversion to O
Welcome to the Wiki of Team Tuebingen!
This year, our project - Tuebingen Erythrocyte Conversion to O (T-ECO) - was all about blood and blood transfusions. You might not have known but donor blood is a really rare resource - not only in hospitals in countries with weak medical infrastructure or in crisis regions after natural disasters but also in ordinary Central European hospitals. Due to the fact that humans have at least four different blood groups and two different Rhesus factors - all antigens on erythrocytes - you cannot simply transfuse any blood you want to any random patient. Thus, hospitals do need to always keep an eye on their stocks lest they they are hit by shortages.
Therefore, we decided to create a practical and easy to use system for the enzymatic conversion of blood types - from blood types A, B and AB to O. Blood type O consists of erythrocytes that do not show any blood type antigens thus can be transfered to any patient and is usually used as emergency donor blood for exactly this reason.
Have a look around our wiki and find out more about our project, the BioBricks we have created, and how we have engaged the general public over the course of this summer!
Sponsors
We want to warmly thank the following sponsors of our iGEM2014 project (in no particular order):
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