<p class="lead">Looking back at the footsteps of evolution, we human being exploit our limits and potentials to adapt mercurial environment and harsh conditions. We have, however, lost some magical potentials in this process. The capability to generate vitamin C for ourselves is one of the lost magics. </p>

         <p align="left">Mutations in L-gulono-gama-lactone oxidase(GLO) gene in many vertebrate species caused the lack of expression of GLO, which leads to a loss of capability to produce vitamin C. As a result of this mutation, many species including human being developed their dependence on food source vitamin C.</p>

         <p align="left">Vitamin C has been playing a pivotal role in scavenging free radical and collagen synthesis. People with long-time insufficient ingestion of vitamin C, sailors for instance, could suffer from scurvy disease. To make matters worse, accumulation of free radical could be an important factor of aging.</p>

         <p align="left">The truth is, we lost the ability to provide an indispensable vitamin to ourselves. And here's what we are working around: can we find out a way to reactivate GLO gene and express functional GLO, hence pick up our long-lost magic? We've conducted cell-level experiments and evaluated their possible effects.</p>

         <img src="https://static.igem.org/mediawiki/2014/2/23/Genefused.png" alt="" class="img-responsive">