<p class="lead">An undesirable mutation deprived one of our beloved magics - providing vitamin C for ourselves. Fortunately, we might be able to pick it up from our ancestors.</p>

         <p align="left">Mutations in L-gulono-gama-lactone oxidase(GLO) gene in many vertebrate species caused the lack of expression of GLO, which leads to a loss of capability to produce vitamin C. As a result of this mutation, many species including human being developed their dependence on food source vitamin C.</p>

         <p align="left">Vitamin C has been playing a pivotal role in scavenging free radical and collagen synthesis. People with long-time insufficient ingestion of vitamin C, sailors for instance, could suffer from scurvy disease. To make matters worse, accumulation of free radical could be an important factor of aging.</p>

         <p align="left">The truth is, we lost the ability to provide an indispensable vitamin to ourselves. And here's what we are working around: can we find out a way to reactivate GLO gene and express functional GLO, hence pick up our long-lost magic? We've conducted cell-level experiments and evaluated their possible effects.</p>

     <p class="lead">Lemur catta，also called Lemur, is a kind of monkey and one of the two species of anthropoids with full and functional GLO gene. Lemur could be a good source of GLO gene if intend to regain our capability of producing vitamin C, just like our ancestors. However, there's still a long way to go.</p>

         <img src="https://static.igem.org/mediawiki/2014/2/23/Genefused.png" alt="" class="img-responsive">

   <p><font size=2.5>Built with love<br>By the iGEM14 team of <a href="http://www.ustb.edu.cn/">University of Science and Technology Beijing</a></font></p>