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Team:UANL Mty-Mexico BETA
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In order to be capable of controlling transformed bacteria and reprogram its function as many times as would be required, we designed a system consisting of a bacteriophage that infects just one specific strain of bacteria and has on its genome the information to codify a TALEN/ZFN enzyme and a reporter gene. With this tools (TALEN/ZFN) we can target a specific sequence of the host's plasmids to degrade them. The bacteriophages will replace the plasmids, giving it a new function or characteristic that could be a totally new one. | In order to be capable of controlling transformed bacteria and reprogram its function as many times as would be required, we designed a system consisting of a bacteriophage that infects just one specific strain of bacteria and has on its genome the information to codify a TALEN/ZFN enzyme and a reporter gene. With this tools (TALEN/ZFN) we can target a specific sequence of the host's plasmids to degrade them. The bacteriophages will replace the plasmids, giving it a new function or characteristic that could be a totally new one. | ||
Revision as of 18:14, 14 October 2014
Template:Team:UANL Mty-Mexico/Main
- Background
- Problem
- Idea
- Solution
OVERVIEW
In order to be capable of controlling transformed bacteria and reprogram its function as many times as would be required, we designed a system consisting of a bacteriophage that infects just one specific strain of bacteria and has on its genome the information to codify a TALEN/ZFN enzyme and a reporter gene. With this tools (TALEN/ZFN) we can target a specific sequence of the host's plasmids to degrade them. The bacteriophages will replace the plasmids, giving it a new function or characteristic that could be a totally new one.
Our Sensor
Check out what we did in the lab this summer to detect E. coli contamination! Learn about the design of our detector, linker, and reporter as well as our prototype and modelling.
Final System
We have shown our final system in action! Click here to see our modeling, talks with industry, and characterization data combine to make a biosensor that can detect DNA in under 5 minutes!
Human Practices
Check out how Human Practices helped guide the development of our project. Learn how we spent time talking to various experts in the industry to design our project with our end-user in mind.
Collaboration
We worked hard with the Paris-Bettencourt team this season to develop useful tools for the rest of the iGEM community. Click here to find out what our collaboration can add to iGEM.
