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| | <div class ="feattext-cell"> | | <div class ="feattext-cell"> |
| | <p class="feattext-p"> | | <p class="feattext-p"> |
| - | We are a <strong>Team</strong> of nine Finnish students and we've gotten amazing support during this project. | + | <h3>Team</h3> |
| | + | We are a Team of nine Finnish students and we've gotten amazing support during this project. |
| | </p> | | </p> |
| | </div> | | </div> |
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| | <div class ="feattext-cell"> | | <div class ="feattext-cell"> |
| | <p class="feattext-p"> | | <p class="feattext-p"> |
| - | We explored the possibilities of biotech and synthetic biology <strong>Business</strong>. | + | <h3>Business</h3> |
| | + | We explored the possibilities of biotech and synthetic biology Business. |
| | </p> | | </p> |
| | </div> | | </div> |
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| | <div class ="feattext-cell"> | | <div class ="feattext-cell"> |
| | <p class="feattext-p"> | | <p class="feattext-p"> |
| - | We <strong>Researched</strong> and engineered a three-channel switch that can be controlled with the intensity of light. | + | <h3>Research</h3> |
| | + | We engineered a three-channel switch that can be controlled with the intensity of light. |
| | </p> | | </p> |
| | </div> | | </div> |
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| | <div class ="feattext-cell"> | | <div class ="feattext-cell"> |
| | <p class="feattext-p"> | | <p class="feattext-p"> |
| - | We studied and made mathematic <strong>Models</strong> of the interactions behind our gene switch. | + | <h3>Modeling</h3> |
| | + | We made mathematic models of the interactions behind our gene switch. |
| | </p> | | </p> |
| | </div> | | </div> |
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| | </a> | | </a> |
| | </div> | | </div> |
| - | <div class="col-md-3 bg feat feat-center bg-cooperation"> | + | <div class="col-md-3 bg feat feat-right bg-cooperation"> |
| | <a href="https://2014.igem.org/Team:Aalto-Helsinki/Cooperation"> | | <a href="https://2014.igem.org/Team:Aalto-Helsinki/Cooperation"> |
| | <div class="feattext-container-tall"> | | <div class="feattext-container-tall"> |
| | <div class ="feattext-cell"> | | <div class ="feattext-cell"> |
| | <p class="feattext-p"> | | <p class="feattext-p"> |
| - | We created tools to make research easier, participated in the Interlab Study and <strong>Cooperated</strong> with other iGEM teams. | + | <h3>Cooperation</h3> |
| | + | We got to know other iGEM teams and developed tools for everyone to use. |
| | </p> | | </p> |
| | </div> | | </div> |
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| | </a> | | </a> |
| | </div> | | </div> |
| - | <div class="col-md-3 bg feat feat-center bg-outreach"> | + | </div> |
| | + | <div class="row row-eq-height"> |
| | + | <div class="col-md-3 bg feat feat-left bg-outreach"> |
| | <a href="https://2014.igem.org/Team:Aalto-Helsinki/Outreach"> | | <a href="https://2014.igem.org/Team:Aalto-Helsinki/Outreach"> |
| | <div class="feattext-container-tall"> | | <div class="feattext-container-tall"> |
| | <div class ="feattext-cell"> | | <div class ="feattext-cell"> |
| | <p class="feattext-p"> | | <p class="feattext-p"> |
| - | We spread the word about iGEM and synthetic biology especially in Finland and conducted <strong>Outreach</strong> with the general public. | + | <h3>Outreach</h3> |
| | + | We spread the word about iGEM and synthetic biology especially in Finland. |
| | </p> | | </p> |
| | </div> | | </div> |
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| | <div class ="feattext-cell"> | | <div class ="feattext-cell"> |
| | <p class="feattext-p"> | | <p class="feattext-p"> |
| - | We documented the project well. You can find everything, and a bit more, from our <strong>Journal</strong>. | + | <h3>Journal</h3> |
| | + | We documented the project well. |
| | </p> | | </p> |
| | </div> | | </div> |
Aalto-Helsinki
Bioworks
Our aim is to build active synthetic biology community in Finland, to learn and share what biotech entrepreneurship takes and to find an open way to build business on synthetic biology.
Aalto-Helsinki Bioworks
A Synthetic Biology Startup with a Three-Channel Gene Switch
We have engineered a three-channel switch that is controlled with the intensity of blue light. By utilizing the mechanisms of the lambda repressor, we are able to switch between the expressions of three different genes with a short delay. This kind of mechanism provides a nearly real-time control over genes, which could provide advantages in variety of industrial bioprocesses.
Inspired by the principles of open source software, we introduce an Open Sequence business model implemented around our switch. We want to encourage future companies to create Open Sequence based solutions and to empower customers to participate in the product development. Open Sequence model’s transparency as well as lower degree of protection raises trust and continuity and benefits larger community.
We want to share our experiences and insights in biotech entrepreneurship and address the difficulties that students and newcomers may face in the early stages of building a synthetic biology startup.
Project Description
We are the first-ever Finnish iGEM Team and one of the three teams in the new entrepreneurship track. Our aim is to build active synthetic biology community in Finland, to learn and share what biotech entrepreneurship takes
and to find an open way to build business on synthetic biology.
We are engineering bacteria whose gene expression can be controlled with blue light. In contrast to previous research, our remote controller is based on light intensity instead of different wavelengths. Thus, we have created a multi-channel switch that requires only one wavelength.
Our device could be used in bioreactors, making prototyping and multi-phase production chains faster, easier and more profitable. We’re making a proof-of-concept controller prototype for research teams, but it can be further scaled up for industrial purposes, such as medical and biofuel industry.
Follow our work on Twitter, Facebook, blog and team web page.
Qualifications
Coming soon(tm).
Categories
Our wiki has seven different categories in addition to this main page. On each of them you can just scroll through the content until you're finished reading. Everything about a subject can be found on one page, additional material is provided when possible and pages that discuss similar stuff are linked to each other.
The seven categories are Team, Business, Research, Modeling, Cooperation, Outreach and Journal. If you find yourself lost (or simply don't know where to start looking for what you'd want to find), here's a sitemap to help with the task!
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