Team:Edinburgh

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        <ul>
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            <li><a href="https://2014.igem.org/Team:Edinburgh">          Home            </a></li>
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            <li><a href="https://2014.igem.org/Team:Edinburgh/Team">      Team            </a></li>
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            <li><a href="https://igem.org/Team.cgi?year=2014&team_name=Edinburgh">Official Profile</a></li>
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            <li><a href="https://2014.igem.org/Team:Edinburgh/Project">  Project        </a></li>
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            <li><a href="https://2014.igem.org/Team:Edinburgh/Parts">    Parts          </a></li>
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            <li><a href="https://2014.igem.org/Team:Edinburgh/Modeling">  Modelling       </a></li>
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            <li><a href="https://2014.igem.org/Team:Edinburgh/Notebook">  Notebook        </a></li>
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            <li><a href="https://2014.igem.org/Team:Edinburgh/Safety">   Safety          </a></li>
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            <li><a href="https://2014.igem.org/Team:Edinburgh/Attributions">Attributions  </a></li>
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<h3 style="font-style: italics;">Our Project: Metabolic Wiring</h3>
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<p>This year the Edinburgh team has created 'metabolic wires' - a novel signalling mechanism for linking logic gates in different cells. By distributing a metabolic pathway among different cells, the outputs of one logic gate can be sent by a diffusible agent to the input of the next logic gate, greatly increasing the potential complexity and intelligence of a synthetic biology system.</p>
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        <p>We are also developing some 'showcase' systems to show these new signals in action.</p>
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<p>Watch this space for updates on how we did, the systems we used to demonstrate this, and more!
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<p>If you think we could collaborate on anything, feel free to <a href="https://twitter.com/EdiGEM2014">get in touch</a>!</p>
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<p>Please enjoy this temporary wiki design while our final design finishes cooking.</p>
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  <h1>RewirED</h1>
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  <p>Smart bacteria could be the computers of the future – but first we have to wire them together. This year Edinburgh is excited to introduce metabolic wiring to iGEM, a novel way for connecting logic gates in different bacterial strains.</p>
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<td><a href="logic/"><img src="https://static.igem.org/mediawiki/2014/8/8e/Bolt.png"></a><br><b>Wiring</b><p>What is metabolic wiring? Click here to hear about the bacterial computation, the benefits it offers, and how metabolic wiring makes it all possible.</p></td>
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<td><img src="https://static.igem.org/mediawiki/2014/a/a7/Ed14_Tube.png"><br><b>Human Practices</b><p>What can our smart bacterial friends tell us about the way human teams work? Are iGEM teams any smarter than a population of smart bacteria?</p></td>
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<td><img src="https://static.igem.org/mediawiki/2014/2/2f/Ed14_Comp.png"><br><b>Modelling</b><p>Why do an experiment when a computer can work out the result? Click here to learn about the models we used, the programs we created, and our collaboration with UCL.</p></td>
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<h2>The Team</h2>
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<td><img src="https://static.igem.org/mediawiki/2014/d/d3/Annastikane.jpg"><br>Anna - Biologist</td>
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<td><img src="https://static.igem.org/mediawiki/2014/3/3a/Carrie.jpg"><br>Carrie - Biologist</td>
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<td><img src="https://static.igem.org/mediawiki/2014/2/21/Cesar.jpg"><br>Cesar - Informatician</td>
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<td><img src="https://static.igem.org/mediawiki/2014/2/21/Charlotte.jpg"><br>Charlotte - Biologist</td>
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</tr><tr>
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<td><img src="https://static.igem.org/mediawiki/2014/f/f5/Chiara.jpg"><br>Chiara - Biologist</td>
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<td><img src="https://static.igem.org/mediawiki/2014/8/8b/Elize.jpg"><br>Elize - Engineer</td>
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<td><img src="https://static.igem.org/mediawiki/2014/1/10/Phillip.jpg"><br>Philip - Biologist</td>
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<td><img src="https://static.igem.org/mediawiki/2014/a/a2/Rikki.jpg"><br>Rikki - Informatician</td>
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</tr><tr>
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<td colspan="2"><img src="https://static.igem.org/mediawiki/2014/2/2e/Sam14.jpg"><br>Sam - Biologist</td>
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<td colspan="2"><img src="https://static.igem.org/mediawiki/2014/c/c9/Yuma.jpg"><br>Yuma - Biologist</td>
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<h2>Our Project</h2>
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<p>Metabolic wires are a new way of connecting logic gates in different cells – their orthogonality and extensibility means there is potentially no limit to how intelligent a population of bacteria can be.</p>
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<p>We set out to make three sets of metabolic wires, using trans-genic aromatic enzymes, cis-genic aromatic genes, and ‘sugar logic.’ We also set out to build a population regulation system to showcase these wires, and a new set of degrons to make the system more robust.</p>
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<h3>Our Sponsors</h3>
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<h2>Our Sponsors</h3>
<img height="100" width="600" src="http://www.sulsa.ac.uk/sites/sbsweb2.bio.ed.ac.uk.sulsa/themes/zen_sulsa/SULSA-logo.png" alt="SULSA"><br>
<img height="100" width="600" src="http://www.sulsa.ac.uk/sites/sbsweb2.bio.ed.ac.uk.sulsa/themes/zen_sulsa/SULSA-logo.png" alt="SULSA"><br>
<img height="100" width="400" src="http://sustainability.benchmarkplc.com/wp-content/uploads/2014/05/MSD-logo.jpg" alr="MSD fund"><br>
<img height="100" width="400" src="http://sustainability.benchmarkplc.com/wp-content/uploads/2014/05/MSD-logo.jpg" alr="MSD fund"><br>
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Revision as of 12:30, 7 October 2014

RewirED

Please enjoy this temporary wiki design while our final design finishes cooking.


Wiring

What is metabolic wiring? Click here to hear about the bacterial computation, the benefits it offers, and how metabolic wiring makes it all possible.


Human Practices

What can our smart bacterial friends tell us about the way human teams work? Are iGEM teams any smarter than a population of smart bacteria?


Modelling

Why do an experiment when a computer can work out the result? Click here to learn about the models we used, the programs we created, and our collaboration with UCL.

The Team


Anna - Biologist

Carrie - Biologist

Cesar - Informatician

Charlotte - Biologist

Chiara - Biologist

Elize - Engineer

Philip - Biologist

Rikki - Informatician

Sam - Biologist

Yuma - Biologist

Our Project

Metabolic wires are a new way of connecting logic gates in different cells – their orthogonality and extensibility means there is potentially no limit to how intelligent a population of bacteria can be.

We set out to make three sets of metabolic wires, using trans-genic aromatic enzymes, cis-genic aromatic genes, and ‘sugar logic.’ We also set out to build a population regulation system to showcase these wires, and a new set of degrons to make the system more robust.

Our Sponsors

SULSA

Biochemistry society
Society of General Microbiology
Society of Biology
BBSRC
Wellcome Trust
ERAsynbio
School of Engineering
School of Biological Sciences
SynthSys
IDT Eppendorf