Team:Georgia State

From 2014.igem.org

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Revision as of 12:14, 16 September 2014

Mamba | Georgia State University

  • slidebg1
    A Solution
    that we need!
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  • slidebg1
    A Solution
    that we need!
    This is a subheadline text sentence
    Sed ut perspiciatis unde omnis iste natus error sit voluptatem
    accusantium doloremque laudantium, totam rem aperiam.
    Button Text

The Problem

We're finding an alternative, and ultimately non-addictive, solution that can be used in place of today's standard painkillers.

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The Solution

Based on current research from leaders in the field, we're proposing the genetic modification and replication of the Mambalgin compound.

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The Process

Utilizing advanced genetic engineering, we've created a unique process by which we can synthesize a new class of pain medications.

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The Applications

Our research is far reaching and has the potential to completely transform the medical industry with non-addictive pain management.

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Mamba: An entry into iGEM 2014

Our team from Georgia State University has been working to successfully insert and purify mambalgin, a protein component of the venom of Dendroaspis Polylepis, better known as the Black Mamba. The mambalgin peptide is a powerful analgesic that directly blocks pain transmission in the peripheral nervous system (Diochot et al, 2012) by targeting acid sensing ion channels within nociceptors beneath the epidermis. Furthermore, recombinant purification of mambalgin could assist in developing anti-venom without the attendant risk of harvesting venom directly from snakes.

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From the Lab

Video Highlights

Introduction to Mamba

From Georgia State University

Our Clients

Partners We Work With

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