Team:Warwick
From 2014.igem.org
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Welcome to the official Wiki of the first University of Warwick 2014 iGEM team. Our team consists of members from different disciplines all having a common interest in the area of Synthetic biology coming together to compete, collaborate and contribute! | Welcome to the official Wiki of the first University of Warwick 2014 iGEM team. Our team consists of members from different disciplines all having a common interest in the area of Synthetic biology coming together to compete, collaborate and contribute! | ||
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Small interfering RNAs (siRNAs) represent a diverse family of biological regulators that are able to bind specifically to mRNA and prevent translation. siRNAs have been used in reverse genetics to understand the function of genes in gene knock-out studies. It has become apparent from a clinical viewpoint that siRNAs represent one type of therapeutic against diseases which have abberant gene expression profilessuch as alzheimers and cancer. | Small interfering RNAs (siRNAs) represent a diverse family of biological regulators that are able to bind specifically to mRNA and prevent translation. siRNAs have been used in reverse genetics to understand the function of genes in gene knock-out studies. It has become apparent from a clinical viewpoint that siRNAs represent one type of therapeutic against diseases which have abberant gene expression profilessuch as alzheimers and cancer. | ||
siRNAs work through a conserved evolutionariy mechanism, specific to eukaryotes that utilizes the enzyme RNAse type 3 enzyme Dicer, that is able to dice a siRNA | siRNAs work through a conserved evolutionariy mechanism, specific to eukaryotes that utilizes the enzyme RNAse type 3 enzyme Dicer, that is able to dice a siRNA | ||
<img style="float: right; margin: 70px 70px 45px 45px;" src="https://static.igem.org/mediawiki/2014/8/8b/RISC.png" width="450" /> | <img style="float: right; margin: 70px 70px 45px 45px;" src="https://static.igem.org/mediawiki/2014/8/8b/RISC.png" width="450" /> | ||
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Revision as of 08:25, 5 August 2014