Team:USyd-Australia

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<tr><td width="30%" align="left"><h3>The Team</h3></br><img src="http://2014.igem.org/wiki/images/3/3c/USyd-Australia_Profile-Abi.jpg" width="100px">
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<tr><td width="30%" align="center"><h3>The Team</h3></td>
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<td align="center"><h3>Integrons: Nature's cloning tool </h3></td>
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<td width="30%" align="center"><h3>Strange Nature</h3></td>
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<td width="30%" align="right"><h3>Strange Nature</h3></br><img src="http://2014.igem.org/wiki/images/a/a8/USyd-Australia_SN-Poster.jpg" width="200px"></td>
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<td colspan="5" align="center">Integrons are natural systems for moving genetic material. They are found in a vast array of bacteria, often associated with rapidly evolving traits such as antibiotic resistance. This is because integrons capture and express mobile genetic elements known as gene cassettes, thus facilitating horizontal gene transfer. Gene cassettes are site selectively recombined by the integron integrase. We have designed BioBrick- compatible integron components that can be used as a novel, convenient and selective cloning system Additionally, we have been investigating regulation of natural transformation mechanisms in E. coli in an attempt to allow uptake and recombination of attC containing genetic elements with added convenience. </td>
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<td colspan="5" align="justify"><a href="http://2014.igem.org/Team:USyd-Australia/Project/Background">Integrons</a> are natural systems for moving genetic material. They are found in a vast array of bacteria, often associated with rapidly evolving traits such as antibiotic resistance. This is because integrons capture and express mobile genetic elements known as gene cassettes, thus facilitating horizontal gene transfer. Gene cassettes are site selectively recombined by the integron integrase. We have <a href="http://2014.igem.org/Team:USyd-Australia/Project/Design">designed</a> BioBrick- compatible integron components that can be used as a novel, convenient and selective cloning system. Additionally, we have been investigating regulation of natural transformation mechanisms in E. coli in an attempt to allow uptake and recombination of attC containing genetic elements with added convenience. </td>
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Latest revision as of 03:41, 18 October 2014

iGEM_Link


The Team

Integrons: Nature's cloning tool

Strange Nature




Integrons as a novel cloning system in E. coli

Integrons are natural systems for moving genetic material. They are found in a vast array of bacteria, often associated with rapidly evolving traits such as antibiotic resistance. This is because integrons capture and express mobile genetic elements known as gene cassettes, thus facilitating horizontal gene transfer. Gene cassettes are site selectively recombined by the integron integrase. We have designed BioBrick- compatible integron components that can be used as a novel, convenient and selective cloning system. Additionally, we have been investigating regulation of natural transformation mechanisms in E. coli in an attempt to allow uptake and recombination of attC containing genetic elements with added convenience.

With thanks to: