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Team:UGA-Georgia/Modeling
From 2014.igem.org
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<p>To increase geraniol yield by mapping the entire lipid biosynthesis pathway in <i>M. maripaludis</i>, performing a genome-scale flux balance analysis and developing strategies for the over production of isoprenoid compounds. </p> | <p>To increase geraniol yield by mapping the entire lipid biosynthesis pathway in <i>M. maripaludis</i>, performing a genome-scale flux balance analysis and developing strategies for the over production of isoprenoid compounds. </p> | ||
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<h5>Results:</h5> | <h5>Results:</h5> | ||
<p>We designed a metabolic model for isoprenoid biosynthesis based upon the complete pathway, including stoichiometric values of acetyl-CoA, ATP, and other compounds required for cell growth. The Biocyc, KEGG, IMG, and SEED databases were used to identify candidate genes/enzymesresponsible for each reaction. </p> | <p>We designed a metabolic model for isoprenoid biosynthesis based upon the complete pathway, including stoichiometric values of acetyl-CoA, ATP, and other compounds required for cell growth. The Biocyc, KEGG, IMG, and SEED databases were used to identify candidate genes/enzymesresponsible for each reaction. </p> | ||
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Revision as of 05:21, 17 October 2014
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Our Model | |||||
Idea:To increase geraniol yield by mapping the entire lipid biosynthesis pathway in M. maripaludis, performing a genome-scale flux balance analysis and developing strategies for the over production of isoprenoid compounds. Results:We designed a metabolic model for isoprenoid biosynthesis based upon the complete pathway, including stoichiometric values of acetyl-CoA, ATP, and other compounds required for cell growth. The Biocyc, KEGG, IMG, and SEED databases were used to identify candidate genes/enzymesresponsible for each reaction. |
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