http://2014.igem.org/wiki/index.php?title=Team:UCL/Science/Bioprocessing&feed=atom&action=historyTeam:UCL/Science/Bioprocessing - Revision history2024-03-28T23:09:29ZRevision history for this page on the wikiMediaWiki 1.16.5http://2014.igem.org/wiki/index.php?title=Team:UCL/Science/Bioprocessing&diff=396361&oldid=prevSanjaycj at 03:22, 18 October 20142014-10-18T03:22:45Z<p></p>
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</table>Sanjaycjhttp://2014.igem.org/wiki/index.php?title=Team:UCL/Science/Bioprocessing&diff=382034&oldid=prevSanjaycj at 01:25, 18 October 20142014-10-18T01:25:38Z<p></p>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p>Optimising process performance at a microfluidic level is often necessary for the economically feasible development of a process due to the small volumes of liquid associated with it. Subsequently, creating a microfluidic prototype device of the large-scale module is extremely relevant in quantifying process variables such as the flow rate to determine residence time of the azo dye suspension within the module. This allows for preliminary mass transfer calculations and azo dye degradation rates.</p> </div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p>Optimising process performance at a microfluidic level is often necessary for the economically feasible development of a process due to the small volumes of liquid associated with it. Subsequently, creating a microfluidic prototype device of the large-scale module is extremely relevant in quantifying process variables such as the flow rate to determine residence time of the azo dye suspension within the module. This allows for preliminary mass transfer calculations and azo dye degradation rates.</p> </div></td></tr>
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</table>Sanjaycjhttp://2014.igem.org/wiki/index.php?title=Team:UCL/Science/Bioprocessing&diff=381826&oldid=prevSanjaycj at 01:23, 18 October 20142014-10-18T01:23:50Z<p></p>
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</table>Sanjaycjhttp://2014.igem.org/wiki/index.php?title=Team:UCL/Science/Bioprocessing&diff=381734&oldid=prevSanjaycj at 01:22, 18 October 20142014-10-18T01:22:58Z<p></p>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><a href="https://2014.igem.org/Team:UCL/Science/MicroF" style="width: 32%;float: left;margin-left:2%;margin-right:2%"><img src="https://static.igem.org/mediawiki/2014/c/c6/Screen_Shot_2014-10-06_at_12.37.15_PM.png" style="max-width: 100%;"></a></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><a href="https://2014.igem.org/Team:UCL/Science/MicroF" style="width: 32%;float: left;margin-left:2%;margin-right:2%"><img src="https://static.igem.org/mediawiki/2014/c/c6/Screen_Shot_2014-10-06_at_12.37.15_PM.png" style="max-width: 100%;"></a></div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Making the microfluidic device. Click on the image to find out more.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Making the microfluidic device. Click on the image to find out more.</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><<del class="diffchange diffchange-inline">br</del>><<del class="diffchange diffchange-inline">br</del>></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><<ins class="diffchange diffchange-inline">!---Sponsor Description End---</ins>></div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><a href="javascript:void(0)" style="width: 32%;float: left;margin-right:0%"><img src="https://static.igem.org/mediawiki/2014/d/d2/Device_trial_.jpg" style="max-width: 100%;"></a></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><a href="javascript:void(0)" style="width: 32%;float: left;margin-right:0%"><img src="https://static.igem.org/mediawiki/2014/d/d2/Device_trial_.jpg" style="max-width: 100%;"></a></div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Introducing pigmented solution into the device at a controlled flow rate as proof of concept. Click on the image to view video.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Introducing pigmented solution into the device at a controlled flow rate as proof of concept. Click on the image to view video.</div></td></tr>
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</table>Sanjaycjhttp://2014.igem.org/wiki/index.php?title=Team:UCL/Science/Bioprocessing&diff=381366&oldid=prevSanjaycj at 01:19, 18 October 20142014-10-18T01:19:39Z<p></p>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><b>Design, fabrication and experimentation of scale-down prototype of immobilisation unit</b></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><b>Design, fabrication and experimentation of scale-down prototype of immobilisation unit</b></div></td></tr>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><a <del class="diffchange diffchange-inline">data-tip="true" class="right large" data-tip-content="Diagram of the first prototype of microfluidic device. It's purpose is to mimic the large scale unit and predict process performance by maintaining geometric similarity. Subsequently, optimisation studies can be performed. " href="javascript:void(0)" </del>style="width: 32%;float: left;margin-left:0%"><img src="https://static.igem.org/mediawiki/2014/8/82/Mfdevice1.png" style="max-width: 100%;"></a></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><a style="width: 32%;float: left;margin-left:0%"><img src="https://static.igem.org/mediawiki/2014/8/82/Mfdevice1.png" style="max-width: 100%;"></a></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div> </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">Diagram of </ins>the <ins class="diffchange diffchange-inline">first prototype of </ins>microfluidic device. <ins class="diffchange diffchange-inline">It's purpose is to mimic </ins>the <ins class="diffchange diffchange-inline">large scale unit and predict process performance by maintaining geometric similarity. Subsequently, optimisation studies can be performed.</ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline"><a data-tip="true" class="bottom large" data-tip-content="Making </del>the microfluidic device. <del class="diffchange diffchange-inline">Click on </del>the <del class="diffchange diffchange-inline">image to find out more" </del>href="https://2014.igem.org/Team:UCL/Science/MicroF" style="width: 32%;float: left;margin-left:2%;margin-right:2%"><img src="https://static.igem.org/mediawiki/2014/c/c6/Screen_Shot_2014-10-06_at_12.37.15_PM.png" style="max-width: 100%;"></a></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline"><br><br></ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div> </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline"><a </ins>href="https://2014.igem.org/Team:UCL/Science/MicroF" style="width: 32%;float: left;margin-left:2%;margin-right:2%"><img src="https://static.igem.org/mediawiki/2014/c/c6/Screen_Shot_2014-10-06_at_12.37.15_PM.png" style="max-width: 100%;"></a></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline"><a data-tip="true" class="bottom large" data-tip-content="Introducing pigmented solution into </del>the device <del class="diffchange diffchange-inline">at a controlled flow rate as proof of concept</del>. Click on the image to <del class="diffchange diffchange-inline">view video</del>.<del class="diffchange diffchange-inline">" </del>href="javascript:void(0)" style="width: 32%;float: left;margin-right:0%"><img src="https://static.igem.org/mediawiki/2014/d/d2/Device_trial_.jpg" style="max-width: 100%;"></a></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">Making </ins>the <ins class="diffchange diffchange-inline">microfluidic </ins>device. Click on the image to <ins class="diffchange diffchange-inline">find out more</ins>.</div></td></tr>
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<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline"><a </ins>href="javascript:void(0)" style="width: 32%;float: left;margin-right:0%"><img src="https://static.igem.org/mediawiki/2014/d/d2/Device_trial_.jpg" style="max-width: 100%;"></a></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">Introducing pigmented solution into the device at a controlled flow rate as proof of concept. Click on the image to view video.</ins></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></p></div></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></p></div></div></td></tr>
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</table>Sanjaycjhttp://2014.igem.org/wiki/index.php?title=Team:UCL/Science/Bioprocessing&diff=374843&oldid=prevSanjaycj at 00:25, 18 October 20142014-10-18T00:25:04Z<p></p>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h4>The future of SABR</h4></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h4>The future of SABR</h4></div></td></tr>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><p>This versatile and simple process offers a wide range of future developments into various chemical producing sectors. The Scaled <del class="diffchange diffchange-inline">BioRemediation </del>strategy has the potential to be integrated as a tertiary treatment option in other industries in the form of a platform technology. Hence, by using different synthetic biology anchors it will be possible to detoxify recalcitrant chemicals that are otherwise difficult to process. With increasing environmental concerns and tighter regulations this would help factories lower toxic discharges, hence decreasing environmental burden.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><p>This versatile and simple process offers a wide range of future developments into various chemical producing sectors. <ins class="diffchange diffchange-inline"><br></ins>The Scaled <ins class="diffchange diffchange-inline">Bioremediation </ins>strategy has the potential to be integrated as a tertiary treatment option in other industries in the form of a platform technology. Hence, by using different synthetic biology anchors it will be possible to detoxify recalcitrant chemicals that are otherwise difficult to process. <ins class="diffchange diffchange-inline"><br></ins>With increasing environmental concerns and tighter regulations this would help factories lower toxic discharges, hence decreasing environmental burden.</div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>The same process design considerations can then be followed: </div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>The same process design considerations can then be followed: </div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><br> 1. Deciding on a chassis and growing a required biomass</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><br> 1. Deciding on a chassis and growing a required biomass</div></td></tr>
</table>Sanjaycjhttp://2014.igem.org/wiki/index.php?title=Team:UCL/Science/Bioprocessing&diff=374768&oldid=prevSanjaycj at 00:24, 18 October 20142014-10-18T00:24:21Z<p></p>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h4>Testing the performance of S.A.B.R unit using microfluidic tools</h4></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h4>Testing the performance of S.A.B.R unit using microfluidic tools</h4></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><p><del class="diffchange diffchange-inline">Optimizing </del>process performance at a microfluidic level is often necessary for the economically feasible development of a process due to the small volumes of liquid associated with it. Subsequently, creating a microfluidic prototype device of the large-scale module is extremely relevant in quantifying process variables such as the flow rate to determine residence time of the azo dye suspension within the module. This allows for preliminary mass transfer calculations and azo dye degradation rates.</p> </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><p><ins class="diffchange diffchange-inline">Optimising </ins>process performance at a microfluidic level is often necessary for the economically feasible development of a process due to the small volumes of liquid associated with it. Subsequently, creating a microfluidic prototype device of the large-scale module is extremely relevant in quantifying process variables such as the flow rate to determine residence time of the azo dye suspension within the module. This allows for preliminary mass transfer calculations and azo dye degradation rates.</p> </div></td></tr>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><b>Design, fabrication and experimentation of scale-down prototype of <del class="diffchange diffchange-inline">immobilization </del>unit</b></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><b>Design, fabrication and experimentation of scale-down prototype of <ins class="diffchange diffchange-inline">immobilisation </ins>unit</b></div></td></tr>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><a data-tip="true" class="right large" data-tip-content="Diagram of the first prototype of microfluidic device. It's purpose is to mimic the large scale unit and predict process performance by maintaining geometric similarity. Subsequently, <del class="diffchange diffchange-inline">optimization </del>studies can be performed. " href="javascript:void(0)" style="width: 32%;float: left;margin-left:0%"><img src="https://static.igem.org/mediawiki/2014/8/82/Mfdevice1.png" style="max-width: 100%;"></a></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><a data-tip="true" class="right large" data-tip-content="Diagram of the first prototype of microfluidic device. It's purpose is to mimic the large scale unit and predict process performance by maintaining geometric similarity. Subsequently, <ins class="diffchange diffchange-inline">optimisation </ins>studies can be performed. " href="javascript:void(0)" style="width: 32%;float: left;margin-left:0%"><img src="https://static.igem.org/mediawiki/2014/8/82/Mfdevice1.png" style="max-width: 100%;"></a></div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><a data-tip="true" class="bottom large" data-tip-content="Making the microfluidic device. Click on the image to find out more" href="https://2014.igem.org/Team:UCL/Science/MicroF" style="width: 32%;float: left;margin-left:2%;margin-right:2%"><img src="https://static.igem.org/mediawiki/2014/c/c6/Screen_Shot_2014-10-06_at_12.37.15_PM.png" style="max-width: 100%;"></a></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><a data-tip="true" class="bottom large" data-tip-content="Making the microfluidic device. Click on the image to find out more" href="https://2014.igem.org/Team:UCL/Science/MicroF" style="width: 32%;float: left;margin-left:2%;margin-right:2%"><img src="https://static.igem.org/mediawiki/2014/c/c6/Screen_Shot_2014-10-06_at_12.37.15_PM.png" style="max-width: 100%;"></a></div></td></tr>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><<del class="diffchange diffchange-inline">h2</del>>The future of SABR</<del class="diffchange diffchange-inline">h2</del>></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><<ins class="diffchange diffchange-inline">h4</ins>>The future of SABR</<ins class="diffchange diffchange-inline">h4</ins>></div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p>This versatile and simple process offers a wide range of future developments into various chemical producing sectors. The Scaled BioRemediation strategy has the potential to be integrated as a tertiary treatment option in other industries in the form of a platform technology. Hence, by using different synthetic biology anchors it will be possible to detoxify recalcitrant chemicals that are otherwise difficult to process. With increasing environmental concerns and tighter regulations this would help factories lower toxic discharges, hence decreasing environmental burden.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p>This versatile and simple process offers a wide range of future developments into various chemical producing sectors. The Scaled BioRemediation strategy has the potential to be integrated as a tertiary treatment option in other industries in the form of a platform technology. Hence, by using different synthetic biology anchors it will be possible to detoxify recalcitrant chemicals that are otherwise difficult to process. With increasing environmental concerns and tighter regulations this would help factories lower toxic discharges, hence decreasing environmental burden.</div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"><br></ins></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>The same process design considerations can then be followed: </div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>The same process design considerations can then be followed: </div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><br> 1. Deciding on a chassis and growing a required biomass</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><br> 1. Deciding on a chassis and growing a required biomass</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><br> 2. Deciding on the <del class="diffchange diffchange-inline">immobilization </del>strategy most adequate for the processing of said chemical by mass transfer considerations.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><br> 2. Deciding on the <ins class="diffchange diffchange-inline">immobilisation </ins>strategy most adequate for the processing of said chemical by mass transfer considerations.</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><br> 3. Adjusting flowrates</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><br> 3. Adjusting flowrates</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><br> 4. Sampling from the recycle loop for online analysis</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><br> 4. Sampling from the recycle loop for online analysis</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div> </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline"><br><br></ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>Moreover, further <del class="diffchange diffchange-inline">characterization </del>of azo dye breakdown by-products will elucidate opportunities to potentially recover usable raw materials, assuming cost efficient methods can be achieved. Our collaboration with Lecturer Godfrey Kyazze at the University of Westminster also revealed promising potential from a thermodynamic point of view. Although operating conditions barely accommodate E.coli, and high prospective costs of industrial implementation with respect to realistic energy production values, the use of azo dye degradation to generate energy through microbial fuel cells could be an exciting development for the future.</p><br></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>Moreover, further <ins class="diffchange diffchange-inline">characterisation </ins>of azo dye breakdown by-products will elucidate opportunities to potentially recover usable raw materials, assuming cost efficient methods can be achieved. Our collaboration with Lecturer Godfrey Kyazze at the University of Westminster also revealed promising potential from a thermodynamic point of view. Although operating conditions barely accommodate E.coli, and high prospective costs of industrial implementation with respect to realistic energy production values, the use of azo dye degradation to generate energy through microbial fuel cells could be an exciting development for the future.</p><br></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Finally, growing concerns regarding water consumption in textile processes due to astronomical usage of ‘potable industrial water’. According to the 2010 global market report on sustainable textiles, the world used three trillion gallons of fresh water to produce 60 billion kilograms of fabric. Establishing a tool for the recycle of textile processing water would not only benefit the environment but lower operating costs of the plant. </div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Finally, growing concerns regarding water consumption in textile processes due to astronomical usage of ‘potable industrial water’. According to the 2010 global market report on sustainable textiles, the world used three trillion gallons of fresh water to produce 60 billion kilograms of fabric. Establishing a tool for the recycle of textile processing water would not only benefit the environment but lower operating costs of the plant. </div></td></tr>
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</table>Sanjaycjhttp://2014.igem.org/wiki/index.php?title=Team:UCL/Science/Bioprocessing&diff=374315&oldid=prevSanjaycj at 00:20, 18 October 20142014-10-18T00:20:27Z<p></p>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><<del class="diffchange diffchange-inline">h2</del>>Testing the performance of S.A.B.R unit using microfluidic tools</<del class="diffchange diffchange-inline">h2</del>></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><<ins class="diffchange diffchange-inline">h4</ins>>Testing the performance of S.A.B.R unit using microfluidic tools</<ins class="diffchange diffchange-inline">h4</ins>></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline"><br> </del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div> </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p>Optimizing process performance at a microfluidic level is often necessary for the economically feasible development of a process due to the small volumes of liquid associated with it. Subsequently, creating a microfluidic prototype device of the large-scale module is extremely relevant in quantifying process variables such as the flow rate to determine residence time of the azo dye suspension within the module. This allows for preliminary mass transfer calculations and azo dye degradation rates.</p> </div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p>Optimizing process performance at a microfluidic level is often necessary for the economically feasible development of a process due to the small volumes of liquid associated with it. Subsequently, creating a microfluidic prototype device of the large-scale module is extremely relevant in quantifying process variables such as the flow rate to determine residence time of the azo dye suspension within the module. This allows for preliminary mass transfer calculations and azo dye degradation rates.</p> </div></td></tr>
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</table>Sanjaycjhttp://2014.igem.org/wiki/index.php?title=Team:UCL/Science/Bioprocessing&diff=374240&oldid=prevSanjaycj at 00:19, 18 October 20142014-10-18T00:19:45Z<p></p>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><<del class="diffchange diffchange-inline">h2</del>>A strong commercial strategy</<del class="diffchange diffchange-inline">h2</del>></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><<ins class="diffchange diffchange-inline">h4</ins>>A strong commercial strategy</<ins class="diffchange diffchange-inline">h4</ins>></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Assessment of commercial feasibility is widely based on evaluating the target market’s “readiness” to receive and integrate an innovative product or process. This primarily involves defining and characterising the target market and quantifying economic potential in terms of projected demand. Furthermore technical feasibility based on forecasted costs and resource requirements must be considered whilst remaining aware of potential risks and obstacles.</p></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Assessment of commercial feasibility is widely based on evaluating the target market’s “readiness” to receive and integrate an innovative product or process. This primarily involves defining and characterising the target market and quantifying economic potential in terms of projected demand. Furthermore technical feasibility based on forecasted costs and resource requirements must be considered whilst remaining aware of potential risks and obstacles.</p></div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>The following clarifies the net and indirect value of our bioprocessing solution to key stakeholders, and elucidates incentive for its integration into current waste management systems.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>The following clarifies the net and indirect value of our bioprocessing solution to key stakeholders, and elucidates incentive for its integration into current waste management systems.</div></td></tr>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><img src="https://static.igem.org/mediawiki/2014/d/db/Arrows.jpg" style="float:right;margin:<del class="diffchange diffchange-inline">0 0 0 </del>10px;" width="<del class="diffchange diffchange-inline">50</del>%"> </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><img src="https://static.igem.org/mediawiki/2014/d/db/Arrows.jpg" style="float:right;margin:<ins class="diffchange diffchange-inline">10 10 10 </ins>10px;" width="<ins class="diffchange diffchange-inline">45</ins>%"> </div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><b>Improving Reputations</b><br></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><b>Improving Reputations</b><br></div></td></tr>
</table>Sanjaycjhttp://2014.igem.org/wiki/index.php?title=Team:UCL/Science/Bioprocessing&diff=374087&oldid=prevSanjaycj at 00:18, 18 October 20142014-10-18T00:18:28Z<p></p>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><br><b>Minimised Contamination</b> of product streams, eliminating the requirement for subsequent protein deactivation and further downstream processing. This is especially important for containment of our recombinant organisms.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><br><b>Minimised Contamination</b> of product streams, eliminating the requirement for subsequent protein deactivation and further downstream processing. This is especially important for containment of our recombinant organisms.</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><br><b>Flow-rates are not limited</b> by a threshold critical value for “biomass washout”, and only impact substrate-catalyst contact time. Catalyst concentrations can remain steady through independence of the dilution rate (see figure 1.3). High volumetric flow-rates can enhance mass transfer and speed up the removal of inhibitors (e.g. Azo-dye metabolites) from the system.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><br><b>Flow-rates are not limited</b> by a threshold critical value for “biomass washout”, and only impact substrate-catalyst contact time. Catalyst concentrations can remain steady through independence of the dilution rate (see figure 1.3). High volumetric flow-rates can enhance mass transfer and speed up the removal of inhibitors (e.g. Azo-dye metabolites) from the system.</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><br></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline"><br></ins><br></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><<del class="diffchange diffchange-inline">h3</del>>Industrial Consultation</<del class="diffchange diffchange-inline">h3</del>></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><<ins class="diffchange diffchange-inline">h4</ins>>Industrial Consultation</<ins class="diffchange diffchange-inline">h4</ins>></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div> </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p>A major part of our project involved engaging with key industrial experts to better understand their wants and needs. We identified the pigment manufacturing and waste water disposal sectors as the two major players who would benefit from our work. By meeting with these leading corporations we have been able to tune our research towards the assenbly of a process that would be most attractive for industry to utilise.</p></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p>A major part of our project involved engaging with key industrial experts to better understand their wants and needs. We identified the pigment manufacturing and waste water disposal sectors as the two major players who would benefit from our work. By meeting with these leading corporations we have been able to tune our research towards the assenbly of a process that would be most attractive for industry to utilise.</p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><br></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><br></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div> </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><<ins class="diffchange diffchange-inline">b</ins>>Meeting with ETAD - Ecological and Toxicological Association of Dye and Pigment Manufacturers</<ins class="diffchange diffchange-inline">b></ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><<del class="diffchange diffchange-inline">h4</del>>Meeting with ETAD - Ecological and Toxicological Association of Dye and Pigment Manufacturers</<del class="diffchange diffchange-inline">h4</del>></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline"><img width="25%" style="float:right;margin:0 0 0 10px;" src="https://static.igem.org/mediawiki/2014/6/67/Etad_logo.jpg"</ins>></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><p>ETAD - an association based in Basel represents over 35 different pigment and dyeing corporations internationally, coordinating a group initiative to limit adverse effects on health and the environment by their industry.Present at the meeting were Walter Hoffman – Director of ETAD, Dr Stefan Ehrenberg - Pigment Manufacturing R&D at Bezema, Georg Roentgen – Director of R&D Colours and Textile Effects at Huntsman.</p></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><p>ETAD - an association based in Basel represents over 35 different pigment and dyeing corporations internationally, coordinating a group initiative to limit adverse effects on health and the environment by their industry.Present at the meeting were Walter Hoffman – Director of ETAD, Dr Stefan Ehrenberg - Pigment Manufacturing R&D at Bezema, Georg Roentgen – Director of R&D Colours and Textile Effects at Huntsman.</p<ins class="diffchange diffchange-inline">><br</ins>></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><p>The main reasons for this meeting were:</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><p>The main reasons for this meeting were:<<ins class="diffchange diffchange-inline">br</ins>></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><<del class="diffchange diffchange-inline">ul</del>></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>To encourage industry to consider synthetic biology as a realistic, viable option when looking to reduce the toxicity of their process.</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline"> <li></del>To encourage industry to consider synthetic biology as a realistic, viable option when looking to reduce the toxicity of their process.<del class="diffchange diffchange-inline"></li></del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><<ins class="diffchange diffchange-inline">br</ins>>Discuss the major concerns and problem areas the dyeing and pigments industry are currently facing.</p></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline"> </del><<del class="diffchange diffchange-inline">li</del>>Discuss the major concerns and problem areas the dyeing and pigments industry are currently facing.<del class="diffchange diffchange-inline"></li></del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline"></ul></del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div></p<del class="diffchange diffchange-inline">></del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline"> <img width="25%" style="float:right;margin:0 0 0 10px;" src="https://static.igem.org/mediawiki/2014/6/67/Etad_logo.jpg"</del>></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div> <br></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div> <br></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div> </div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div> </div></td></tr>
</table>Sanjaycj