Team:Tufts

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<h1 style="color:white">Tufts iGEM 2014</h1>
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<a href="https://2014.igem.org/Team:Tufts"style="color:#0099FF">Home </a> </td>
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<a href="https://2014.igem.org/Team:Tufts/Team"style="color:#0099FF"> Team </a> </td>
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<a href="https://igem.org/Team.cgi?year=2014&team_name=Tufts"style="color:#0099FF"> Official Team Profile </a></td>
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        Tufts iGEM seeks to expand undergraduate science education and allow students to take part in all aspects of the research process, from drafting proposals, to securing funding, and finally carrying out the research in lab. These projects expose students not only to the technical aspects of synthetic biology but also to the social, legal, and ethical implications generated by their work. The team is composed of passionate individuals from all fields of study, who are driven to investigate and address pertinent issues in medicine, health, technology, research, and bioethics. In addition to carrying out undergraduate, self-directed research, the Tufts iGEM team teaches and mentors underclassmen, develops relationships with professors, and generally works to promote the involvement of undergraduates in biological research.
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<a href="https://2014.igem.org/Team:Tufts/Project"style="color:#0099FF"> Project</a></td>
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<a href="https://2014.igem.org/Team:Tufts/Parts"style="color:#0099FF"> Parts</a></td>
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<a href="https://2014.igem.org/Team:Tufts/Modeling"style="color:#0099FF"> Modeling</a></td>
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<a href="https://2014.igem.org/Team:Tufts/Notebook"style="color:#0099FF"> Notebook</a></td>
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<a href="https://2014.igem.org/Team:Tufts/Safety"style=" color:#0099FF"> Safety </a></td>
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<a href="https://2014.igem.org/Team:Tufts/Attributions"style="color:#0099FF"> Attributions </a></td>
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<!--This year, we are competing in the International Genetically Engineered Machine (iGEM) Competition
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with a project which uses a bacteriophage to block the formation of biofilms. We have received a grant
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from the European Commission’s SYNENERGENE Project which aims to initiate and foster public
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dialogue on synthetic biology and mutual learning processes among a wide variety of stakeholders from
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In fulfillment of this grant, we are pursuing two avenues. The first is the writing of “application
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scenarios” and “techno-moral scenarios” meant to discuss the feasibility and desirability of applications
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of our iGEM projects. The second is the organization and hosting of a one day conference on
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bacteriophage.
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The conference, titled The Future of Phage and Synthetic Biology, incorporates two events. The first a
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professional workshop that brings together leaders of industry, regulation, and research to discuss and
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advance a pre-written framework on the intersection of bacteriophage application and associated safety
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biology, bacteriophage, and antibiotic resistance by means of a survey. The survey will be disseminated
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orally by Penn Schoen Berland (PSB) Research and online through Tufts Qualtrics.
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<h2>Robust biofilm formation using a cyclic-di-GMP aptamer and investigating ethics and applications of engineered bactiophage</h2>
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A long, noncoding massively expressed regulatory RNA (merRNA) discovered in Bdellovibrio bacteriovorus is present in high levels during its dormant phase. The merRNA is believed to sequester cyclic-di-GMP, much like a sponge. Since cyclic-di-GMP is a second messenger for various cellular functions, including motility and biofilm formation, the Tufts iGEM team introduced this merRNA sequence into E. coli. Constitutive expression of this merRNA transcript was shown to increase biofilm formation. This property can be useful in microbe-based approaches to environmental remediation. Earlier designs for phage delivery of the merRNA to disrupt biofilms inspired an investigation into the policy surrounding engineered bacteriophage. Tufts iGEM will be convening a panel of experts from various disciplines to put forth recommendations for the responsible use of phage in therapeutic and industrial applications. A proposal will be drafted for a silk bandage containing a phage cocktail which can prevent and treat infection by antibiotic-resistant bacteria.
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<p> Please be sure to keep these links, your audience will want to find your: </p>
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<li><a href="https://2014.igem.org/Team:Tufts">Home</a> </li>
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<li><a href="https://2014.igem.org/Team:Tufts/Team">Team</a> </li>
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<li><a href="https://igem.org/Team.cgi?year=2013&team_name=Tufts">Official Team Profile</a> </li>
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<li><a href="https://2014.igem.org/Team:Tufts/Project">Project</a> </li>
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<li><a href="https://2014.igem.org/Team:Tufts/Parts">Parts</a> </li>
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<li><a href="https://2014.igem.org/Team:Tufts/Modeling">Modeling</a> </li>
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<li><a href="https://2014.igem.org/Team:Tufts/Notebook">Notebook</a> </li>
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<li><a href="https://2014.igem.org/Team:Tufts/Safety">Safety</a> </li>
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<li><a href="https://2014.igem.org/Team:Tufts/Attributions">Attributions</a> </li>
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<li>All pages must be created under the team’s name space.</li>
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<li>As part of your documentation, keep the links from the menu to the left. </li>
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<li>Do not use flash in wiki code. </li>
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<li>The <a href="https://static.igem.org/mediawiki/igem.org/6/60/Igemlogo_300px.png"> iGEM logo </a> should be placed on the upper part of every page and should link to <a href="https://2014.igem.org/Main_Page">2014.igem.org</a>.</li>
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<p>Visit the <a href="https://2014.igem.org/Wiki_How-To"> Wiki How To page </a> for a complete list of requirements, tips and other useful information. </p>
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<p>We are currently working on providing teams with some easy to use design templates.
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<li> <a href="https://2013.igem.org/Team:SDU-Denmark/"> 2013 SDU Denmark </a> </li>
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<li> <a href="https://2013.igem.org/Team:SYSU-China">2013 SYSU China</a> </li>
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<li> <a href="https://2013.igem.org/Team:Shenzhen_BGIC_ATCG"> 2013 Shenxhen BGIG ATCG </a></li>
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<li> <a href="https://2013.igem.org/Team:Colombia_Uniandes">2013 Colombia Unianades </a></li>
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<li> <a href="https://2013.igem.org/Team:Lethbridge">2013 Lethbridge</a></li>
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<p>For a full wiki list, you can visit <a href="https://igem.org/Team_Wikis?year=2013">iGEM 2013 web sites </a> and <a href="https://igem.org/Team_Wikis?year=2012">iGEM 2012 web sites</a>  lists. </p>
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<p>This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started: </p>
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<li>Be clear about what you are doing and what you plan to do.</li>
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<li>You have a global audience! Consider the different backgrounds that your users come from.</li>
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<li>Make sure information is easy to find; nothing should be more than 3 clicks away.  </li>
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<li>Avoid using very small fonts and low contrast colors; information should be easy to read.  </li>
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<li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="">iGEM 2013 calendar</a> </li>
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<li>Have lots of fun! </li>
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Latest revision as of 01:34, 18 October 2014

Tufts University

Tufts iGEM seeks to expand undergraduate science education and allow students to take part in all aspects of the research process, from drafting proposals, to securing funding, and finally carrying out the research in lab. These projects expose students not only to the technical aspects of synthetic biology but also to the social, legal, and ethical implications generated by their work. The team is composed of passionate individuals from all fields of study, who are driven to investigate and address pertinent issues in medicine, health, technology, research, and bioethics. In addition to carrying out undergraduate, self-directed research, the Tufts iGEM team teaches and mentors underclassmen, develops relationships with professors, and generally works to promote the involvement of undergraduates in biological research.

Retrieved from "http://2014.igem.org/Team:Tufts"