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Team:Toulouse/Project/Fungicides
From 2014.igem.org
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<p> Originated from plants, these peptides have different target to maximize the lethality on C. platani. | <p> Originated from plants, these peptides have different target to maximize the lethality on C. platani. | ||
<p> | <p> | ||
| - | - D4E1 is a synthetic peptide made of 17 amino acids which has been shown to have an antifungal activity by complexing with a sterol present in the conidia’s wall of numerous fungi. </p> | + | - <g>D4E1</g> is a synthetic peptide made of 17 amino acids which has been shown to have an antifungal activity by complexing with a sterol present in the conidia’s wall of numerous fungi. </p> |
<p> | <p> | ||
Revision as of 12:14, 1 October 2014
Fungicides
To eradicate fungal diseases
Project > Fungicides
The main objective of SubtiTree is to ensure the destruction of the pathogenic fungi inside the tree. In order to achieve this goal, we built a genetic module to produce three different peptides with antifungal activities.
Originated from plants, these peptides have different target to maximize the lethality on C. platani.
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- GAFP-1 (Gastrodia Anti Fungal Protein 1) is a lectin binding to mannose thus inhibiting the growth of a variety of fungi.
- EcAMP-1 (Echinochloa crus-galli Anti Microbial Peptide) consists in 37 amino acids inhibiting hyphae elongation.
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