Team:TCU Taiwan

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<meta name="description" content="This WIKI Web is about TCU_Taiwan iGEM project in 2014.The International Genetically Engineered Machine competition (iGEM) is the premiere undergraduate Synthetic Biology competition. Student teams are given a kit of biological parts at the beginning of the summer from the Registry of Standard Biological Parts. Working at their own schools over the summer, they use these parts and new parts of their own design to build biological systems and operate them in living cells." />
<meta name="description" content="This WIKI Web is about TCU_Taiwan iGEM project in 2014.The International Genetically Engineered Machine competition (iGEM) is the premiere undergraduate Synthetic Biology competition. Student teams are given a kit of biological parts at the beginning of the summer from the Registry of Standard Biological Parts. Working at their own schools over the summer, they use these parts and new parts of their own design to build biological systems and operate them in living cells." />
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<h1 style="color:#F35A4A"><b><font face="Trebuchet MS" size="6">This Website currently under construction!</font></b></h1>
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<p><font face="Trebuchet MS" size="7" color="#A66B38">TCU_Taiwan</font></p><br>
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<p style="color:#F3F0CD"><font size="3" face="Verdana">Welcome to our new Internet domain!
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<p style="color:#90B849"><font size="4" face="Verdana">Welcome to our Wiki Page!
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<br>Our WIKI will be online soon.<br> Thank you for your patience while we build site.Please visit again.
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</font><p>Or go to
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<h3><a href="http://tcuigem.wordpress.com/" target="_blank">Our Blog</a> and    Facebook</h3>
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     <td align="center"><p><font face="Trebuchet MS" size="6" color="#9FE0F6"><img src="https://static.igem.org/mediawiki/2014/f/f4/TCU-Project-logo.png" width="65">&nbsp;Project Overview</font></p>
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     <td align="center"><br><br><p><font face="Trebuchet MS" size="7" color="#9FE0F6"><img src="https://static.igem.org/mediawiki/2014/f/f4/TCU-Project-logo.png" width="65">&nbsp;Project Overview</font></p>
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     <p align="left"><font size="3" face="Verdana" color="#F3F0CD" >Bacterial resistance to antibiotics has been a problem for public health, and the problem is getting worse.We are trying to develop a CRISPR system combined with phage transduction to solve this problem.<br><br>The type II CRISPR system is a powerful tool for gene editing, it uses Cas9 protein, which is guided by either a tracrRNA-crRNA or a simplified gRNA, to bind the target gene and creates a double-strand break, therefore knockout the target gene. This system has been proved to have more efficient than other tool such as zinc finger or TALEN. However CRISPR can only function within one cell, so we use M13 phage as vector to send our CRISPR into bacteria cells to remove the antibiotic resistance gene.</font></p>
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     <p align="justify"><font size="4" face="Verdana" color="#F3F0CD" >This year, TCU_Taiwan provide a new tool dealing with bacterial antibiotic resistance - the Trogene Horse. Our Trogene Horse can produce one-generation phage carrying CRISPR system with particular signal.</font></p>
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     <p align="justify"><font size="4" face="Verdana" color="#F3F0CD" >Trogene Horse is a new concept combining phage therapy with CRISPR, and this combination can solve both safety concern(phage therapy) and efficiency problem(CRISPR). We believe our project can deal with bacterial resistance problem on agriculture, and hope it can access on medicine one day.</font></p><br><br><br><br>
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    <td align="center"><font face="Trebuchet MS" size="6" color="#F3F0CD"><img src="https://static.igem.org/mediawiki/2014/c/cc/TCU-Anti.png" width="55px">For additional information , please click the boxes.</font></td>
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     <td width="33%" style="background:#F2B441" align="center"><p>&nbsp;</p>
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       <p><a href="https://2014.igem.org/Team:TCU_Taiwan/Project"><img src="https://static.igem.org/mediawiki/2014/0/0f/TCU-Project-p.GIF" width="100" height="100"></a></p>
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<font size="5">Under construction!</font><br >
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<source src="https://static.igem.org/mediawiki/2014/9/95/TCU-Taiwan_An_Introduction_of_Trogene_Horse_%28720p%29.mov" type="video/mp4">
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<a href="https://static.igem.org/mediawiki/2014/9/95/TCU-Taiwan_An_Introduction_of_Trogene_Horse_%28720p%29.mov"><br>Download the video.</a>
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     <td style="background:#F2B441" align="center"><p><a href="https://2014.igem.org/Team:TCU_Taiwan/Modeling"><img src="https://static.igem.org/mediawiki/2014/3/3e/TCU-Modeling.GIF" width="100" height="100"></a></p>
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    <a href="http://english.moe.gov.tw/" title="Ministry of Education,Republic of China" target="_blank"><img src="https://static.igem.org/mediawiki/2014/8/83/TCU_Moe_logo_BLACK.png" height="100" onMouseMove="this.src=Image3.src" onMouseOut="this.src='https://static.igem.org/mediawiki/2014/8/83/TCU_Moe_logo_BLACK.png'"></a>&nbsp;&nbsp;&nbsp;
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    <a href="http://tec.tcu.edu.tw/100/" title="Center of Teaching Excellence,TCU" target="_blank"><img src="https://static.igem.org/mediawiki/2014/2/26/TCU_TEACH_BLACK.png" height="100" onMouseMove="this.src=Image1.src" onMouseOut="this.src='https://static.igem.org/mediawiki/2014/2/26/TCU_TEACH_BLACK.png'"></a>&nbsp;&nbsp;
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Latest revision as of 21:35, 17 October 2014

TCU_Taiwan


Welcome to our Wiki Page!

 

 Project Overview


This year, TCU_Taiwan provide a new tool dealing with bacterial antibiotic resistance - the Trogene Horse. Our Trogene Horse can produce one-generation phage carrying CRISPR system with particular signal.

Trogene Horse is a new concept combining phage therapy with CRISPR, and this combination can solve both safety concern(phage therapy) and efficiency problem(CRISPR). We believe our project can deal with bacterial resistance problem on agriculture, and hope it can access on medicine one day.





  
For additional information , please click the boxes.

 

 

 

 

 

 

 




           



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