Team:SCUT/HP/Magazine/iGEM People

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<img src="https://static.igem.org/mediawiki/2014/7/7e/HP-9-1.jpg">
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Scientists Move Closer to Inventing Artificial Life
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The Exclusive Interview of the Founding Captain of Jilin University’s iGEM Team
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科学家真的做出了人造生命?
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It is reported that an international team has inserted a man-made chromosome into brewer's yeast, producing a life form that thrives and successfully passes the designer genes on to its offspring.
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In our last interview, we have introduced the founding captain of iGEM SCUT team——Zhang  Junjie to you. This time, I’m going to introduce you the founding captain of Jilin University’s IGEM team, Han jia, a blossoming man of science who have always wanted to become a Public educator. In the following passage I will share you why he wants to become an educator, what he has done to contribute to the dynamic synthetic biology as well as his experience of importing IGEM to his university and how he forged his own team.
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据报道,一支由各国科学家组成的科研队伍近日将人造染色体成功导入啤酒酵母(我们常喝的青岛啤酒、珠江啤酒都是由靠这种重要的可食用菌发酵产生的哦!!!)内,创造出了可以独立健康成长并可将改造后的基因传给子孙后代的一种生命体形式。这一实验结果意味着人类在创造生命的路途上迈出了重要的第一步。下面我们就来具体看看这一全新生命体是如何被创造出来的。
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The meeting lasting 2 days was organized by HZAU, WHU and HUST iGEM teams. The contents consisted of three main parts: senior iGEMers’ reports, project presentation by each team, and the discussion of debugs in experiments. On the morning of 23th  August, Dr. Tang Jun, the professor of HZAU participated in the opening ceremony and gave a welcoming speech. Then we watched the video made by the chairman iGEM Head Quarters specially for the meeting. It was really helpful and wonderful. After the opening ceremony, the seniors Zhang Haoqian and Liu Yang coming from Peking University and Ocean University of China gave us two important speeches, sharing their abundant experience about iGEM. It really paid to learn.
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1. The growth process of Han
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Chromosomes are the packages for genes. In plants, animals, and fungi like yeast, they are contained within a cell nucleus, which simpler microbes like bacteria do not have. People have 23 pairs of chromosomes, and yeasts have 16. Best known for their role in baking bread and brewing beer, yeasts share about a third of their genes with people.
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HanJia began reading a lot of educational books, such as pedagogical psychology at a young age, and became interested in pedagogy. Afterwards he started to become an enthusiast on studying the educational joint projects,and he even involved in many fields of study including economics,ethnics ,psychology, philosophy, management, arts, and medicine, this reading process of absorbing various aspects of knowledge has greatly enriched his study of the life science. When Hanjia first went to the university, he started to be active in child education & community services together with his like-minded friends, and from then on, he had set his heart on a career in the cause of education. Although he gave up his dream career temporarily for many reasons afterwards, he learned great deal from this practices and he indeed made a lot of practical and useful proposals to his old school : Jilin University and Shenyang Pharmaceutical University. To conclude,he is a  man with kindness,conscience and public spirits,and he dares to face any challenge and tries his best to overcame them uitimately.
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染色体是基因的集中体。在植物、动物和真菌等真核生物中,染色体存在于细胞核中;而在简单低等的原核生物如细菌,染色体和细胞核都是不存在的。相对于人类的23对染色体,用于酿酒和制作面包的酵母只有16对,并且酵母基因的三分之一都是人类基因中可以找到的。
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2. Academic career
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(Pic 1 The budding yeast is just like roast photo with delicious sausage.
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The present goal of Han is to become a researcher of Beijing Life Science Research Center.And he had already done researches in the labs of Jilin University for 2 years and a half as an exchange student of Joint training of Life Science College of Jilin University. During that time, he not only achieved many challenging academic studies, but also joined substantial practical activities. In Dec. 2011, he became a researcher of the Key Laboratory of Ministry of education Jilin University molecular enzyme engineering, and joined the "Jilin University undergraduate innovation experiment research" as a project leader. Then he studied in Zhang Zuoming’ project called Molecular cloning and characterization of cellulose CpCel9 and its mutants in Enzyme engineering 204 which then enriched his knowledge about Enzyme engineering. He is also a cure researcher of the academic department of the College of life science as well as the school committee of science and technology association propaganda department director who helped to hold "Jilin University" Challenge Cup "Gold Award", "team six campus cup" Impulse Cup "campus marketing competition" and "Jilin University" top ten students selection”. What’s more he also managed to hold the “meeting of exchange of learning in School of Biology”, “meeting of exchange of learning between Research and Undergraduates” and many other academic activities.
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图为正在出芽的啤酒酵母,看起来像不像一个土豆盖着许多片烤香肠呢?
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嘿嘿,是不是又饿了^_^)
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After his exchange experience, he went back to Shenyang Pharmaceutical University to continue to do other science researches. And he joined in the Lab of Xi Huanzhang to study Joint related technology transfer gene transfer method and the research of gene function, which grew his interest in Aminoglycoside antibiotics combinatorial biosynthesis related with microbial agents and synthetic biology research.
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Tolerant of genetic tinkering, yeast played a role in a previous synthetic biology breakthrough, when scientists led by J. Craig Venter assembled the first artificial bacterial genome inside yeast cells in 2009. And man-made DNA strips cooked up inside yeasts, so-called yeast artificial chromosomes (YACs), have been used to make gene maps for decades. Yeast was one of the first organisms to have its entire genome sequenced, in 1996.
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3. Liking for iGEM
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由于对基因改造有很好的耐受性,酵母在以往合成生物学的重大突破中都扮演了很重要的角色。2009年,以J.Craig Venter为首的科学家们在酵母细胞中组建了第一个人工细菌基因。另外,酵母中的某些DNA被人工敲除(使酵母中原有的一些可以表达的基因沉默不能表达,从而抑制相关生物功能),改造成为酵母人造染色体(YAC),多年来都被用作构建基因图谱。1996年,酵母成为第一个被全部测序的有机体。
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During the talk with team leader Mr.Han, we found that it is even more accidental comparing to Mr.Zhang who was introduced last time.  
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The new study's "synIII" artificial chromosome implanted into brewer's yeast builds on this legacy. It crowns a seven-year "Build a Genome" project that involved more than 60 biologists in its assembly.
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Mr Han told us that it is the movie" there we were" arouse his interest in Peking university and the school life there. Then he started going through lots of videos about there. By chance, he found the video about the iGEM team in Peking university. From then, the little seed was growing in his heart , which bring him the dream that one day he would has his own team taking this top competition in biology filed. During his year 2. He joined the lecture which was given by the researcher, Li Yan from the institute of microbiology as well as the summer camp in Shanghai Jiaotong university which are all quite relevant to iGEM. All of these brought him more and more close to synthetic biology ,and laying the foundation of establish the iGEM team here.
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这项将“synIII”人造染色体植入啤酒酵母中的研究全部建立在上述基础上。它被称为“7年构建一个基因组”项目,共有60多位生物学家参与它的构建。
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Essentially, the study researchers created a stripped-down, but still functional, third chromosome of brewer's yeast, which contains about 2.5 percent of the organism's total genes.
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Through indefatigable effort of university, teachers and students, the IGEM team from the Jilin University is formally launched on 2014. The team is led by Wu Yongge subdecanal, Mr. Liu Chengbo, Mr. Gao Chaohui, Mr. Jiang Yiqun and Ms. Wu hui as the co - director of the team, Han Jia and Du Bochuan as the team leader, Song Guangyuan and other sophomores as principal members,and around other 20 students from the freshmen to seniors who are interested on the scientific research join the team. Then this team is named as Jilin-China as suggested by the organising committee; meanwhile, they jointly create the IGEM China Community and Synbiclub together with other colleges, to facilitate further scholarly communication exchanges.
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从本质上讲,这项研究的研究人员创造了一个更为精简但功能齐全的含有三分之一的原有染色体和2.5%基因总量的啤酒酵母。
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“This is a major step towards being able to design completely novel organisms," says Todd Kuiken of the Woodrow Wilson International Center for Scholars in Washington, D.C. "The research team has created what some might call the first synthetic cell that was designed, built and reproduced without a host cell present," he says.
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(Pic 1 Han Jia and his instructor, Prof. Teng)
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“这是迈向设计出全新生物体的重要一步。“华盛顿特区Woodrow Wilson国际学者中心的Todd Kuiken说,“研究小组已经创造出第一个合成细胞,它能够不需要宿主细胞的存在而自主设计、构建和复制。”
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Still awaiting scientists is the assembly of a complete artificial genome: man-made versions of all the chromosomes in a plant or animal.
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Finally, after October ,2013,  the iGEM team from Nanjing university who won the gold prize and entered the international competition came to Jilin university to introduce the iGEM.  At that time, Mr Han has already in his final year . When he hear this news, he decided to back Changchun right away , starting to form the first iGEM team for his mother school -- Jilin university .
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仍有待科学家们完成的是一个完整的人造基因组的组装构建:所有动植物的人造基因组。
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Ideally, synthetic biology will produce microbes with specific genetic codes embedded to cheaply churn out renewable fuels or medicines such as the antimalarial drug artemisinin.
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When he came back to school, he started pushing this issue with his schoolmates and friend  Du Bochuan. They introduced iGEM to junior students during the college welcome party and also brought this news to the deputy dean professor Teng Rongli.  Prof. Teng  gave great support and encouraged them to go further. Step by step, the dream of iGEM team has become more clear and workable. Meanwhile, Mr Han became more  confident to build iGEM team in Jilin university.
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科学家的理想是,合成生物学能够创造出植入特定基因的工程菌,这些工程菌可以廉价生产出可再生燃料和像抗疟药青蒿素这样的高成本药物。
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At the present time, they has entered a tense phase of experimental stages, everything are new, they come up against a great deal of resistance in dealing with many problems, but they always try their best to overcome all the difficulties. The main project for the IGEM team is regarding the degradation of algae toxins technology in water to reduce the pollution and purify the environment. Here, we would like to express our great gratitude to the team leader Mr. Hanjia for his help on the interview, and we wish that his team will perform well in the coming competition this year.
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Latest revision as of 21:36, 17 October 2014

The Exclusive Interview of the Founding Captain of Jilin University’s iGEM Team

In our last interview, we have introduced the founding captain of iGEM SCUT team——Zhang Junjie to you. This time, I’m going to introduce you the founding captain of Jilin University’s IGEM team, Han jia, a blossoming man of science who have always wanted to become a Public educator. In the following passage I will share you why he wants to become an educator, what he has done to contribute to the dynamic synthetic biology as well as his experience of importing IGEM to his university and how he forged his own team.

The meeting lasting 2 days was organized by HZAU, WHU and HUST iGEM teams. The contents consisted of three main parts: senior iGEMers’ reports, project presentation by each team, and the discussion of debugs in experiments. On the morning of 23th August, Dr. Tang Jun, the professor of HZAU participated in the opening ceremony and gave a welcoming speech. Then we watched the video made by the chairman iGEM Head Quarters specially for the meeting. It was really helpful and wonderful. After the opening ceremony, the seniors Zhang Haoqian and Liu Yang coming from Peking University and Ocean University of China gave us two important speeches, sharing their abundant experience about iGEM. It really paid to learn.

1. The growth process of Han

HanJia began reading a lot of educational books, such as pedagogical psychology at a young age, and became interested in pedagogy. Afterwards he started to become an enthusiast on studying the educational joint projects,and he even involved in many fields of study including economics,ethnics ,psychology, philosophy, management, arts, and medicine, this reading process of absorbing various aspects of knowledge has greatly enriched his study of the life science. When Hanjia first went to the university, he started to be active in child education & community services together with his like-minded friends, and from then on, he had set his heart on a career in the cause of education. Although he gave up his dream career temporarily for many reasons afterwards, he learned great deal from this practices and he indeed made a lot of practical and useful proposals to his old school : Jilin University and Shenyang Pharmaceutical University. To conclude,he is a man with kindness,conscience and public spirits,and he dares to face any challenge and tries his best to overcame them uitimately.

2. Academic career

The present goal of Han is to become a researcher of Beijing Life Science Research Center.And he had already done researches in the labs of Jilin University for 2 years and a half as an exchange student of Joint training of Life Science College of Jilin University. During that time, he not only achieved many challenging academic studies, but also joined substantial practical activities. In Dec. 2011, he became a researcher of the Key Laboratory of Ministry of education Jilin University molecular enzyme engineering, and joined the "Jilin University undergraduate innovation experiment research" as a project leader. Then he studied in Zhang Zuoming’ project called Molecular cloning and characterization of cellulose CpCel9 and its mutants in Enzyme engineering 204 which then enriched his knowledge about Enzyme engineering. He is also a cure researcher of the academic department of the College of life science as well as the school committee of science and technology association propaganda department director who helped to hold "Jilin University" Challenge Cup "Gold Award", "team six campus cup" Impulse Cup "campus marketing competition" and "Jilin University" top ten students selection”. What’s more he also managed to hold the “meeting of exchange of learning in School of Biology”, “meeting of exchange of learning between Research and Undergraduates” and many other academic activities.

After his exchange experience, he went back to Shenyang Pharmaceutical University to continue to do other science researches. And he joined in the Lab of Xi Huanzhang to study Joint related technology transfer gene transfer method and the research of gene function, which grew his interest in Aminoglycoside antibiotics combinatorial biosynthesis related with microbial agents and synthetic biology research.

3. Liking for iGEM

During the talk with team leader Mr.Han, we found that it is even more accidental comparing to Mr.Zhang who was introduced last time.

Mr Han told us that it is the movie" there we were" arouse his interest in Peking university and the school life there. Then he started going through lots of videos about there. By chance, he found the video about the iGEM team in Peking university. From then, the little seed was growing in his heart , which bring him the dream that one day he would has his own team taking this top competition in biology filed. During his year 2. He joined the lecture which was given by the researcher, Li Yan from the institute of microbiology as well as the summer camp in Shanghai Jiaotong university which are all quite relevant to iGEM. All of these brought him more and more close to synthetic biology ,and laying the foundation of establish the iGEM team here.

Through indefatigable effort of university, teachers and students, the IGEM team from the Jilin University is formally launched on 2014. The team is led by Wu Yongge subdecanal, Mr. Liu Chengbo, Mr. Gao Chaohui, Mr. Jiang Yiqun and Ms. Wu hui as the co - director of the team, Han Jia and Du Bochuan as the team leader, Song Guangyuan and other sophomores as principal members,and around other 20 students from the freshmen to seniors who are interested on the scientific research join the team. Then this team is named as Jilin-China as suggested by the organising committee; meanwhile, they jointly create the IGEM China Community and Synbiclub together with other colleges, to facilitate further scholarly communication exchanges.

(Pic 1 Han Jia and his instructor, Prof. Teng)

Finally, after October ,2013, the iGEM team from Nanjing university who won the gold prize and entered the international competition came to Jilin university to introduce the iGEM. At that time, Mr Han has already in his final year . When he hear this news, he decided to back Changchun right away , starting to form the first iGEM team for his mother school -- Jilin university .

When he came back to school, he started pushing this issue with his schoolmates and friend Du Bochuan. They introduced iGEM to junior students during the college welcome party and also brought this news to the deputy dean professor Teng Rongli. Prof. Teng gave great support and encouraged them to go further. Step by step, the dream of iGEM team has become more clear and workable. Meanwhile, Mr Han became more confident to build iGEM team in Jilin university.

At the present time, they has entered a tense phase of experimental stages, everything are new, they come up against a great deal of resistance in dealing with many problems, but they always try their best to overcome all the difficulties. The main project for the IGEM team is regarding the degradation of algae toxins technology in water to reduce the pollution and purify the environment. Here, we would like to express our great gratitude to the team leader Mr. Hanjia for his help on the interview, and we wish that his team will perform well in the coming competition this year.