Team:SCUT-China/Modeling/Simulation

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Simulation

Reactions and Mechanism



1.Mechanism



The model for enzyme action, first suggested by Brown and Henri but later established more thoroughly Michaelis and Menten, suggests the binding of free enzyme to the substrate forming a enzyme-substrate(ES) complex. This complex undergoes a transformation, releasing product and free enzyme. The free enzyme is then available for another round of binding to new substrate.

In the single substrate enzyme catalyzed reactions, the mechanism is often written as: