Team:Pitt

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<h1 id = "top">Introduction</h1>
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<iframe style = "float:right;margin:15px;margin-right:100px;" src="//player.vimeo.com/video/101982329?title=0&amp;byline=0&amp;portrait=0&amp;color=f6694b" width="500" height="281" frameborder="0" webkitallowfullscreen mozallowfullscreen allowfullscreen></iframe>
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<p style = "width:180px;margin-left:100px;margin-right:30px;margin-top:40px;">The goal of 2014 Pitt iGEM team was to find a better treatment of acne using skin bacteria. Acne is a common skin condition, yet current treatments are ineffective and/or harmful. Using genes from the iGEM Registry of Parts, we pioneered a new treatment for acne opening the door for future skin probiotics.</p>
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<br><br><br><br><br><br><br>
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<h2>Project Background</h2>
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<p style = "margin:20px;margin-left:40px;">In the same way the Human Genome Project provides a wealth of knowledge on how our cells function, the <a href="http://commonfund.nih.gov/hmp/overview">Human Microbiome Project</a> is uncovering how our cells thrive within a vast microbial community. Research shows how healthy bacteria contribute to our well-being by protecting our bodies against more pathogenic bacteria.<br><br>
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Propionibacterium acnes is one of these common, healthy microbes that thrives in the sebum (oil) secreted by the skin of the face, chest, and back. Studies have associated certain strains of P. acnes with acne vulgaris, but the link is unclear. Unfortunately, research on P. acnes is scarce because current technologies for genetic engineering do not work on P. acnes. In addition to an array of skin probiotics, the 2014 Pitt iGEM Team has developed a genetic engineering chassis to aid further study of P. acnes.</p>
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<br><br>
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<h2>Press</h2>
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•<a href="http://www.post-gazette.com/local/city/2014/09/29/Competition-spurs-genetics-research-from-Pitt-CMU-students/stories/201409290214">Competition spurs genetics research from Pitt, CMU students</a>
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<br>•<a href="https://experiment.com/projects/living-skin-therapeutics">Crowdfunding raises $1,900 for U. Pitt Research Team</a>
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<h1 >WELCOME TO iGEM 2014! </h1>
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<p>Your team has been approved and you are ready to start the iGEM season!
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<br>On this page you can document your project, introduce your team members, document your progress <br> and share your iGEM experience with the rest of the world! </p>
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<p style="color:#E7E7E7"> <a href="https://2014.igem.org/wiki/index.php?title=Team:Pitt&action=edit"style="color:#FFFFFF"> Click here  to edit this page!</a> </p>
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<a href="https://2014.igem.org/Team:Pitt"style="color:#000000">Home </a> </td>
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<a href="https://2014.igem.org/Team:Pitt/Team"style="color:#000000"> Team </a> </td>
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<a href="https://igem.org/Team.cgi?year=2014&team_name=Pitt"style="color:#000000"> Official Team Profile </a></td>
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<a href="https://2014.igem.org/Team:Pitt/Modeling"style="color:#000000"> Modeling</a></td>
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<a href="https://2014.igem.org/Team:Pitt/Attributions"style="color:#000000"> Attributions </a></td>
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<p> Please be sure to keep these links, your audience will want to find your: </p>
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<li><a href="https://2014.igem.org/Team:Pitt">Home</a> </li>
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<li><a href="https://2014.igem.org/Team:Pitt/Team">Team</a> </li>
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<li><a href="https://igem.org/Team.cgi?year=2013&team_name=Pitt">Official Team Profile</a> </li>
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<li><a href="https://2014.igem.org/Team:Pitt/Project">Project</a> </li>
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<li><a href="https://2014.igem.org/Team:Pitt/Parts">Parts</a> </li>
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<li><a href="https://2014.igem.org/Team:Pitt/Modeling">Modeling</a> </li>
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<li><a href="https://2014.igem.org/Team:Pitt/Notebook">Notebook</a> </li>
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<p>We are currently working on providing teams with some easy to use design templates.
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<br> In the meantime you can also view other team wikis for inspiration! Here are some very good examples</p>
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<li> <a href="https://2013.igem.org/Team:SDU-Denmark/"> 2013 SDU Denmark </a> </li>
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<li> <a href="https://2013.igem.org/Team:SYSU-China">2013 SYSU China</a> </li>
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<li> <a href="https://2013.igem.org/Team:Shenzhen_BGIC_ATCG"> 2013 Shenxhen BGIG ATCG </a></li>
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<li> <a href="https://2013.igem.org/Team:Colombia_Uniandes">2013 Colombia Unianades </a></li>
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<li> <a href="https://2013.igem.org/Team:Lethbridge">2013 Lethbridge</a></li>
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<p>For a full wiki list, you can visit <a href="https://igem.org/Team_Wikis?year=2013">iGEM 2013 web sites </a> and <a href="https://igem.org/Team_Wikis?year=2012">iGEM 2012 web sites</a>  lists. </p>
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<li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="">iGEM 2013 calendar</a> </li>
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Latest revision as of 00:21, 18 October 2014

Introduction

The goal of 2014 Pitt iGEM team was to find a better treatment of acne using skin bacteria. Acne is a common skin condition, yet current treatments are ineffective and/or harmful. Using genes from the iGEM Registry of Parts, we pioneered a new treatment for acne opening the door for future skin probiotics.









Project Background


In the same way the Human Genome Project provides a wealth of knowledge on how our cells function, the Human Microbiome Project is uncovering how our cells thrive within a vast microbial community. Research shows how healthy bacteria contribute to our well-being by protecting our bodies against more pathogenic bacteria.

Propionibacterium acnes is one of these common, healthy microbes that thrives in the sebum (oil) secreted by the skin of the face, chest, and back. Studies have associated certain strains of P. acnes with acne vulgaris, but the link is unclear. Unfortunately, research on P. acnes is scarce because current technologies for genetic engineering do not work on P. acnes. In addition to an array of skin probiotics, the 2014 Pitt iGEM Team has developed a genetic engineering chassis to aid further study of P. acnes.




Press

Competition spurs genetics research from Pitt, CMU students
Crowdfunding raises $1,900 for U. Pitt Research Team

Next Page