Team:NYMU-Taipei/modeling/m3

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threshold model

purpose & introduction

How to control the starting time of phage killing?

We use multiple terminators to make a threshold of the production of endolysin, so we build this model to determine the number of terminators.

system

$$\frac{d[\text{lysis gene mRNA}]}{dt} = \beta\frac{[\text{comE}]^n}{K_d+[\text{comE}]^n}(1-a)^w-[\text{lysis gene mRNA}]K_m$$

result

discussion